Long-Acting HIV Prevention Injection Approved in England and Wales
Cabotegravir, the first long-acting injectable drug for HIV prevention, has been approved to be used in England and Wales. This development is expected to benefit approximately 1,000 individuals at risk of HIV, offering a long-acting alternative to existing preventive medications that must be taken daily as oral pills. Cabotegravir is an antiretroviral medication that was […]
Two Studies on the Role of Appearance Concerns in Social Anxiety and Depression
Behav Ther. 2025 Nov;56(6):1082-1095. doi: 10.1016/j.beth.2025.05.002. Epub 2025 May 14. ABSTRACT Appearance concerns are a core feature of multiple psychiatric disorders, including body dysmorphic disorder and eating disorders; however, some have argued that they may also play a key role in social anxiety and depression. The present study sought to determine whether reductions in appearance […]
From Ocean to Organ: Seaweed Scaffolds Pave the Way for Sustainable Tissue Engineering
The study title Development and Optimization of Decellularized Seaweed Scaffolds for Tissue Engineering highlights how Devaleraea mollis (Pacific dulse), a red marine seaweed, can serve as a sustainable plant-based scaffold for tissue engineering applications. Pacific dulse contains high amounts of cellulose and bioactive substances and has a fibrous structure that resembles the natural extracellular matrix, […]
Feasibility of digital application-based information and follow-up in day-care surgery
Dan Med J. 2025 Oct 15;72(11):A11240772. doi: 10.61409/A11240772. ABSTRACT INTRODUCTION: The rapid adoption of digital health solutions highlights the potential benefits of mobile-based follow-up care. This study examines the feasibility of implementing a digital pain management app for post-operative follow-up in a Danish surgical department. METHODS: A feasibility study was conducted based on the framework […]
Reliability and Validity of Nutrient Assessment Applications for Canadian Endurance Athletes: MyFitnessPal and Cronometer
J Hum Nutr Diet. 2025 Oct;38(5):e70148. doi: 10.1111/jhn.70148. ABSTRACT INTRODUCTION: The purpose of the present observational study was to assess the inter-rater reliability and validity of two free nutrition apps, MyFitnessPal (MFP) and Cronometer (CRO), among Canadian endurance athletes. METHODS: Two raters independently input 43 three-day food intake records (FIR) (27M/16F) into MFP and CRO, […]
‘I went home not feeling prepared from the outset’: describing the co-design of a technological solution to address gaps in the transition from hospital to home for people with acquired brain injury
Brain Impair. 2025 Dec 23;26(4):IB25006. doi: 10.1071/IB25006. ABSTRACT People with acquired brain injury (ABI) experience difficulties returning to everyday life post hospital discharge, despite specialised inpatient rehabilitation. This study sought to describe the co-design process of a project that aimed to explore how technology could be used to better prepare people with ABI for the […]
Experience-based co-design of a smartphone app for post-stroke aphasia self-management: a process evaluation
Brain Impair. 2025 Dec 23;26(4):IB24127. doi: 10.1071/IB24127. ABSTRACT BACKGROUND: Experience-based co-design (EBCD) is a well-established method to engage patients, family members and healthcare professionals in the co-design of interventions. A key principle of EBCD is equal partnership. For adults with acquired communication disabilities, additional measures are required to ensure authentic, rather than tokenistic, engagement. The […]
Evaluating the Efficacy of a Digital Therapeutic Intervention for Temporomandibular Disorders: Multicenter, Randomized, Sham-Controlled Trial
J Med Internet Res. 2025 Oct 24;27:e83545. doi: 10.2196/83545. ABSTRACT BACKGROUND: Temporomandibular disorders (TMDs) are common chronic musculoskeletal conditions associated with pain, jaw dysfunction, and impaired quality of life and influenced by behavioral and psychological factors. Digital therapeutics (DTx) may improve access to standardized behavioral interventions, but their clinical efficacy for TMD has not been […]
Gyroscope-constrained magnetometer PDR/Wi-Fi indoor positioning algorithm
PLoS One. 2025 Oct 24;20(10):e0335277. doi: 10.1371/journal.pone.0335277. eCollection 2025. ABSTRACT To address the issue of low precision in sensor data measured by smartphones, we propose a gyroscope-constrained magnetometer Pedestrian Dead Reckoning (PDR)/Wi-Fi indoor positioning algorithm, focusing on improving the PDR heading angle. We utilize the heading angle constrained by the gyroscope and magnetometer and enhance […]
COVID-19 mRNA Vaccine-Induced Immune Modulation Enhances Checkpoint Blockade Efficacy
Messenger RNA (mRNA) vaccines were designed to prevent infectious diseases, including COVID-19. They are now recognized for their capacity to stimulate potent innate and adaptive immune responses. The immunostimulatory effects may go beyond viral protection to impact cancer immunotherapy results. Immune checkpoint inhibitors (ICIs) rely on pre-existing antitumor immunity and show limited efficacy in patients […]
