A feasibility study evaluating the usability and acceptability of the personalised space technology exercise platform mobile application

Sci Rep. 2025 Oct 17;15(1):36370. doi: 10.1038/s41598-025-20314-0. ABSTRACT The P-STEP (Personalised Space Technology Exercise Platform) app is designed to bring together tailored exercise guidance and up-to-date air quality information for individuals with long term health conditions. The app allows individuals to plan outdoor exercise walking routes while minimising their exposure to air pollution. Individuals with […]

GPT-4o and the quest for machine learning interpretability in ICU risk of death prediction

BMC Med Inform Decis Mak. 2025 Oct 13;25(1):373. doi: 10.1186/s12911-025-03224-z. ABSTRACT BACKGROUND: Clinical utilization of machine learning is hampered by the lack of interpretability inherent in most non-linear black box modeling approaches, reducing trust among clinicians and regulators. Advanced large language models offer a potential framework for integrating medical knowledge into these models, potentially enhancing […]

Exploring Feature Preferences for a Treatment-Accompanying App in Patients Undergoing Radiation Therapy: Cross-Sectional Study

JMIR Cancer. 2025 Oct 15;11:e68411. doi: 10.2196/68411. ABSTRACT BACKGROUND: Mobile health (mHealth) apps are playing an increasingly important role in health care, including in radiotherapy. However, adherence remains low. One way to increase adherence is to tailor app features to the patients’ preferences. OBJECTIVE: This study aimed to explore the importance of patient preferences regarding […]

A Previsit Mobile Health App (Health-E You/Salud iTu) for Male Adolescents to Promote Sexual and Reproductive Health Care Receipt: Protocol for a Randomized Controlled Trial

JMIR Res Protoc. 2025 Oct 15;14:e77780. doi: 10.2196/77780. ABSTRACT BACKGROUND: Male adolescents have significant sexual and reproductive health (SRH) needs and, despite the existence of national guidelines, their SRH care receipt remains poor. Technology-based interventions have been shown to successfully support adolescents’ SRH; however, they have primarily focused on female individuals. To date, no such […]

Piloting a cancer awareness app across six European countries: a pre-post study

Front Public Health. 2025 Sep 29;13:1648212. doi: 10.3389/fpubh.2025.1648212. eCollection 2025. ABSTRACT BACKGROUND: Cancer remains a significant public health challenge in Europe, accounting for over 22% of global cancer cases. Mobile health applications may help to increase the awareness of cancer risks and preventive behaviors. However, usability barriers and disparities in digital health literacy (DHL) may […]

GamblingLess: In-The-Moment: a mixed-methods acceptability and engagement evaluation of a gambling just-in-time adaptive intervention

Addict Sci Clin Pract. 2025 Oct 14;20(1):80. doi: 10.1186/s13722-025-00608-4. ABSTRACT BACKGROUND: Mobile health interventions, particularly dynamic Just-In-Time Adaptive Interventions (JITAIs), can overcome barriers to gambling treatment by offering timely, accessible support in people’s everyday lives. GamblingLess: In-The-Moment is a theoretically-informed and evidence-based app-delivered JITAI to people who want to quit or reduce their gambling. The […]

Adherence to mHealth quit smoking application ‘stopcoach’ on top of evidence based smoking cessation counselling: association with participant characteristics and long-term abstinence

Subst Abuse Treat Prev Policy. 2025 Oct 14;20(1):44. doi: 10.1186/s13011-025-00672-8. ABSTRACT BACKGROUND: Smoking is more common in lower socioeconomic position (SEP) groups, but smoking cessation interventions are less effective for these groups. StopCoach, an mHealth intervention, supports people with lower SEP in quitting smoking. A non-randomized controlled trial found that adding StopCoach to accredited smoking […]

Heart Failure Patients Can Now Treat Edema at Home with FDA Approved Lasix® ONYU

at home treatment for edema

The United States Food and Drug Administration (USFDA) has approved Lasix® ONYU (furosemide injection) for the treatment of edema in adults with chronic heart failure. This drug was developed by Ligand Pharmaceuticals’ partner, SQ Innovation Inc., as a novel drug-device combination that allows subcutaneous self-administration at home under clinician guidance without requiring a healthcare professional’s […]

Isolation, Engineering, and Ecology of Temperate Phages in the Human Gut

The human gut contains a large and dynamic microbial ecosystem that includes numerous bacteriophages. Temperate phages capable of lysogeny play an important role in shaping bacterial diversity, facilitating gene exchange, and maintaining ecological stability. Recent metagenomic advances have revealed immense viral diversity within the gut microbiome; however, the functional behavior and induction dynamics of prophages […]

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