Use and User Experience of a Preconception Lifestyle App for Couples Undergoing in Vitro Fertilization: Mixed Methods Study
JMIR Hum Factors. 2025 Oct 14;12:e65815. doi: 10.2196/65815. ABSTRACT BACKGROUND: Mobile apps are a promising way to improve healthy lifestyle behavior among people with infertility. However, sufficient engagement with mobile health apps is crucial to influence health outcomes, and identifying features to create more effective interventions is urgently needed. OBJECTIVE: This study conducted a process […]
Preferences for HIV/STI Prevention mHealth Features Among Rural Sexual Minority Men in the South
AIDS Educ Prev. 2025 Oct;37(5):364-378. doi: 10.1521/aeap.2025.37.5.364. ABSTRACT This study identified the preferred features of HIV/STI prevention mobile health (mHealth) apps among rural sexual minority men (SMM) in the southern U.S. and examined preference differences by HIV risk factors. Participants (N = 406) completed an online cross-sectional survey. A series of multiple logistic regression models […]
Implementing a Digital Mental Health Intervention-the Lumi Nova App-to Support Children With Anxiety in Economically Disadvantaged Areas: Mixed Methods Study
J Med Internet Res. 2025 Oct 14;27:e60611. doi: 10.2196/60611. ABSTRACT BACKGROUND: Anxiety is one of the most common mental health problems experienced by children worldwide. In the United Kingdom, many children experiencing anxiety do not receive adequate or timely help. Children living in economically disadvantaged areas experience more mental health problems than those living in […]
Exploring Fit in a Mobile Health Intervention for Alcohol Use Disorder: Qualitative Study
JMIR Mhealth Uhealth. 2025 Oct 14;13:e65218. doi: 10.2196/65218. ABSTRACT BACKGROUND: Implementation frameworks such as the Exploration, Preparation, Implementation, Sustainment model emphasize the importance of the fit between an intervention and its context, which includes the needs of its target population, as well as the culture, resources, and capabilities of the implementing organization. Although lack of […]
Rebuilding the Brain’s Defense: A New Path to Alzheimer’s Recovery

A groundbreaking study published in Signal Transduction and Targeted Therapy by Junyang Chen et al. describes a novel therapeutic amyloid-beta clearance and cognitive recovery by repairing the blood-brain barrier rather than merely bypassing it. The researchers focused on the low-density lipoprotein receptor-related protein 1, which is called LRP1 and is crucial for removing amyloid beta […]
Global Mortality and Life Expectancy Trends, 1950–2021: Insights from the GBD 2021 Study

Life expectancy and age-specific mortality are key demographic indicators to monitor global health and identify emerging trends. The COVID-19 pandemic highlighted the critical need for timely estimates of all-cause mortality to guide effective public health responses and policymaking. Traditional demographic tools often face limitations in data availability and analytical speed, specifically during crises. The Global […]
Digital Interventions for Stimulant Use Among People Living with HIV: A Narrative Review
Curr HIV/AIDS Rep. 2025 Oct 13;22(1):49. doi: 10.1007/s11904-025-00758-9. ABSTRACT PURPOSE OF REVIEW: Stimulant use, which includes use of cocaine and methamphetamine, is known to worsen care outcomes among people living with HIV (PLWH). The rise of stimulant use in the United States (US) in the last decade is a threat to the US plan of […]
Smartphone use in a large US adult population: Temporal associations between objective measures of usage and mental well-being
Proc Natl Acad Sci U S A. 2025 Oct 28;122(43):e2427311122. doi: 10.1073/pnas.2427311122. Epub 2025 Oct 13. ABSTRACT Smartphones are essential tools in daily life yet concerns persist about their potential effects on mental health and well-being. Research on these relationships often relies on subjective measures of smartphone use, which can lack validity. These studies are […]
Artificial intelligence-driven prediction and interpretation of central line-associated bloodstream infections in ICU: insights from the MIMIC-IV database
Front Public Health. 2025 Sep 25;13:1675077. doi: 10.3389/fpubh.2025.1675077. eCollection 2025. ABSTRACT OBJECTIVE: To develop and internally validate interpretable machine learning (ML) models for predicting individual central line-associated bloodstream infection (CLABSI) risk in adult ICU patients with central venous catheters (CVCs) using the MIMIC-IV database. METHODS: We conducted a retrospective observational cohort study using the MIMIC-IV […]
Linking workplace incivility to turnover outcomes in nursing
J Health Organ Manag. 2025 Oct 13;39(6):1195-1216. doi: 10.1108/JHOM-06-2024-0246. ABSTRACT PURPOSE: This paper investigates the relationship between workplace incivility (WI) and nurses’ job and vocational turnover intentions. We introduce two moderators, organizational efficacy (OE) and calling and investigate their influence on the relationship between WI and turnover intentions. DESIGN/METHODOLOGY/APPROACH: We surveyed 187 nurses in the […]


