The Role of Educational Interactive Virtual Simulation App in Aesthetic Medicine and Cosmetic Dermatology Preclinical Skills
J Cosmet Dermatol. 2025 Oct;24(10):e70496. doi: 10.1111/jocd.70496. ABSTRACT BACKGROUND: The rapid progress in the field of aesthetic medicine and cosmetic dermatology drives the demand for skilled healthcare practitioners able to provide safe, complex treatments accurately and confidently. Traditional training approaches, which emphasize didactic teaching and little hands-on experience, typically fail to prepare postgraduate students for […]
Self-Help App for Depression in People With Intellectual Disabilities: A Randomized Clinical Trial
JAMA Netw Open. 2025 Oct 1;8(10):e2536364. doi: 10.1001/jamanetworkopen.2025.36364. ABSTRACT IMPORTANCE: Individuals with intellectual disabilities (IDs) are at increased risk for mental health problems, including depression. However, access to effective therapeutic interventions is often limited. OBJECTIVE: To evaluate the feasibility, acceptance, and efficacy of a self-help smartphone app designed to reduce depressive symptoms and improve self-esteem […]
Cerina-Cognitive Behavioral Therapy-Based Mobile App for Managing Generalized Anxiety Disorder Symptoms Among University Students: Results From a Pilot Feasibility Randomized Controlled Trial
JMIR Mhealth Uhealth. 2025 Oct 9;13:e70691. doi: 10.2196/70691. ABSTRACT BACKGROUND: Generalized anxiety disorder (GAD) is common among university students due to academic pressure and financial uncertainty, among other challenges. Despite the need, the receipt of available psychological services is often low. OBJECTIVE: This study investigates the feasibility of a digital unguided cognitive behavioral therapy (CBT)-based […]
Development and Evaluation of a Persian-Language Self-Management Mobile Application for People With Spinal Cord Injury
Health Expect. 2025 Oct;28(5):e70454. doi: 10.1111/hex.70454. ABSTRACT INTRODUCTION: Spinal cord injury (SCI) is associated with complex complications and long-term disability. Mobile health applications are crucial for managing their complications and challenges, given their high adoption rate among these patients. While previous studies have developed and evaluated self-management mobile applications for SCI in other languages and […]
Machine Learning (ML) Algorithm to Predict Mortality of Trauma Patients Admitted to the Intensive Care Units (ICU) in Northwest Ethiopia
Nurs Crit Care. 2025 Nov;30(6):e70190. doi: 10.1111/nicc.70190. ABSTRACT BACKGROUND: Predicting mortality among trauma patients is a critical task that can guide clinical decision-making, better management and resource allocation in Intensive Care Units (ICU). Machine learning has been increasingly employed in clinical practice to effectively predict the mortality of critically ill patients. AIM: This study aimed […]
Barriers and Facilitators to Women’s Careers in Academic Cardiology: A Multicenter Qualitative Analysis
J Am Heart Assoc. 2025 Oct 7;14(19):e043329. doi: 10.1161/JAHA.125.043329. Epub 2025 Sep 25. ABSTRACT BACKGROUND: Women remain underrepresented in cardiology. The culture of academic cardiology is referenced as a barrier to inclusivity. Surveys provide a limited understanding of experiences faced by female cardiologists. The purpose of this study was to characterize organizational cultural barriers and […]
Breakthrough Discovery on Immune System’s Self-Control Wins Nobel Prize
The 2025 Nobel Prize in Physiology or Medicine has been awarded to Shimon Sakaguchi from Japan, and Mary Brunkow and Fred Ramsdell from the United States, for their groundbreaking discovery revealing how the immune system targets harmful foreign organisms while avoiding attacks on the body’s own cells. The three researchers will share 11 million Swedish […]
New Study Finds Late-Life Traumatic Brain Injury Increases Dementia Risk in Older Adults
Over one million Canadians aged 65 years and older are expected to experience a traumatic brain injury (TBI) in their lifetime, and most frequently caused by falls. TBI is clinically diagnosed following a direct or indirect hit on the head, along with any of the symptoms like confusion, weakness, memory loss, loss of consciousness, changes […]
SMOC1 Identified as a Therapeutic Target in β-Cell Failure and Type 2 Diabetes
Type 2 diabetes is caused by β-cell dysfunction and impaired insulin secretion. The underlying molecular and cellular mechanisms are not completely understood. Recent advances in single-nucleus and single-cell RNA sequencing (snRNA-seq and scRNA-seq) have shed light on the complex heterogeneity of pancreatic islet cells. These technologies enable the identification of distinct subpopulations of β and […]
Impact of Digital Phenotypes and Question-Asking on Emotional Disorders in Adolescents: 4-Week Field Study
JMIR Hum Factors. 2025 Oct 7;12:e66536. doi: 10.2196/66536. ABSTRACT BACKGROUND: Adolescence is the period with the highest incidence of mental disorders, with approximately one-third, half, and two-thirds of cases emerging by ages 14, 18, and 25 years, respectively. Proactive interventions are essential, and digital phenotyping has emerged as a promising approach for timely detection and […]
