FDA Grants First-Ever Approval for Barth Syndrome Therapy
The Barth Syndrome Foundation (BSF) is a patient advocacy organisation dedicated to saving lives through research aimed at curing Barth syndrome, advancing therapies, and providing education. In September 2025, elamipretide was approved by the USFDA for treating Barth syndrome, which is marketed under the brand name FORZINITY. The FDA has authorised this medication as the […]
Trump and Kennedy Unveil Bold Plan to Combat Autism Crisis
President Donald J. Trump and HHS Secretary Robert F. Kennedy, Jr. announced bold new initiatives to address the increasing autism spectrum disorder (ASD) crisis in the United States in the Roosevelt Room. The prevalence of autism has increased nearly 400% since 2000, and currently, one in 31 children in the U.S. lives with autism. Secretary […]
Harnessing digital phenotyping to advance university student mental health (Brightline) in Singapore: study protocol for a prospective observational study
BMJ Open. 2025 Sep 22;15(9):e103652. doi: 10.1136/bmjopen-2025-103652. ABSTRACT INTRODUCTION: Mental health issues such as depression and anxiety are highly and disproportionally prevalent among university students. Beyond the academic rigour, stressors imposed by a new environment result in them being vulnerable to the onset and manifestation of mental health symptomatology. Leveraging smartphones and wearables for digital […]
A smartphone-integrated colorimetric and fluorescent sensor for monitoring salmon freshness
Anal Chim Acta. 2025 Nov 8;1374:344525. doi: 10.1016/j.aca.2025.344525. Epub 2025 Aug 8. ABSTRACT BACKGROUND: Salmon is a tasty and nutritious fish that is widely welcomed by consumers worldwide. However, salmon is susceptible to spoilage and generates biogenic amines (BAs), which are detrimental to human health upon ingestion. Traditional testing methods are often cumbersome and time-consuming, […]
Immune Recognition of Airborne Allergens is Reduced by Far (UV222) Exposure
Most allergic reactions are triggered by reactions with one or more exogenous protein allergens from these sources, which constitute most allergic reactions. A controlled experimental system was created to produce respirable particles (≤10 μm) that consist of common aeroallergens, including mold, mites, and pollen, both in purified forms and dust. One-third of adults and children […]
MBX Biosciences’ Canvuparatide Shows Strong and Durable Response in Hypoparathyroidism Patients
MBX Biosciences is a clinical-stage biopharmaceutical company focused on developing novel precision peptide therapies for metabolic and endocrine diseases. It has announced a promising Phase 2 result from the Avail™ trial evaluating canvuparatide. It is a once-weekly treatment for chronic hypoparathyroidism (HP). The 12-week randomized phase of the trial met its primary endpoint with statistical […]
Light-PTNet: A lightweight parallel temporal network for smartphone-based human motion classification
PLoS One. 2025 Sep 23;20(9):e0331135. doi: 10.1371/journal.pone.0331135. eCollection 2025. ABSTRACT The increased popularity of smartphone-based human activity recognition (HAR) in recent decades has been driven by its low computational requirements and user privacy protection. Yet, developing a reliable smartphone-based HAR still presents several challenges. For example, handcrafted feature-based approaches highly depend on laborious feature engineering/selection […]
Respiratory-Responsive Vocal Biomarker for Asthma Exacerbation Monitoring: Prospective Cohort Study
J Med Internet Res. 2025 Sep 23;27:e68741. doi: 10.2196/68741. ABSTRACT BACKGROUND: Asthma exacerbations remain a major challenge in asthma management, often due to delayed recognition and limitations of conventional monitoring tools such as peak flow meters and symptom questionnaires. These tools are typically effort dependent or retrospective, making them less suited for continuous, real-time monitoring. […]
App-Based Smoking Urge Reduction Intervention for Young Adults: Protocol Combining a Microrandomized Trial and Conventional Between-Subject Randomized Trial
JMIR Res Protoc. 2025 Sep 23;14:e74388. doi: 10.2196/74388. ABSTRACT BACKGROUND: Tobacco smoking is the leading preventable cause of morbidity and mortality in the United States, and young adults have high smoking rates. Although most young adult smokers are interested in quitting, they underutilize professional cessation support. Smartphones have wide reach and integration into young adults’ […]
Beyond Pigment Pathways: Redefining the Genetics of Foveal Development
The fovea is a specialized region of the retina essential for high-acuity vision. Its pathogenesis includes the movement of inner retinal layers and the congestion of cone photoreceptors. Arrested formation results in foveal hypoplasia (FH), a condition usually associated with albinism, nystagmus, and reduced visual acuity. Established genetic causes of FH largely involve pigmentation pathways […]
