Smartphone-Compatible Colorimetric Detection of CA19-9 Using Melanin Nanoparticles and Deep Learning
Biosensors (Basel). 2025 Aug 5;15(8):507. doi: 10.3390/bios15080507. ABSTRACT Paper-based colorimetric biosensors represent a promising class of low-cost diagnostic tools that do not require external instrumentation. However, their broader applicability is limited by the environmental concerns associated with conventional metal-based nanomaterials and the subjectivity of visual interpretation. To address these challenges, this study introduces a proof-of-concept […]
All-in-One Sustainable Thread Biosensor for Chemiluminescence Smartphone Detection of Lactate in Sweat
Biosensors (Basel). 2025 Aug 13;15(8):530. doi: 10.3390/bios15080530. ABSTRACT Thanks to their low-cost, portability, and sustainability, microfluidic thread-based analytical devices (μTADs) are emerging as an attractive analytical platform for wearable biosensing. While several μTADs, mainly based on colorimetric and electrochemical detection methods, have been developed, achieving the needed sensitivity and accuracy for these biosensors continues to […]
The Silent Shift in Health Language that Parents Shouldn’t Ignore
The Make America Healthy Again (MAHA) movement has attracted attention not only for its public health objectives, but also for the way it frames health and disease in its language. Advocates from the disability and chronic illness communities have expressed concerns that the Make America Healthy Again movement constructs health in stigmatizing ways, often shifting […]
AABB Clinical Practice Guideline on RBC Transfusion in Acute MI
Red blood cell (RBC) transfusion thresholds are based on levels of hemoglobin (Hb) according to the Association for the Advancement of Blood & Biotherapies (AABB) guidelines. These guidelines recommend a conservative technique (<7 g/dL) to decrease the risks and preserve the blood supply. However, their safety in patients with acute myocardial infarction (AMI) remains uncertain. […]
First Maryland Case of New World Screwworm: What You Need to Know
The first U.S. case of New World screwworm linked to international travel has been reported in Maryland. The patient, a state resident who had recently visited El Salvador, was diagnosed by the Centers for Disease Control and Prevention (CDC). Maryland health officials stated that the individual has recovered well. Investigators reported no such transmission into […]
Rewiring Fear: Human Brain Study Unlocks Extinction Mechanisms
A recent study published in Nature Human Behaviour examined how to help the brain learn to overcome fear. This offers new hope for therapy for anxiety disorders. The researchers examined the neurophysiological mechanisms underlying fear extinction, the process of reducing conditioned fears through repeated exposure to a neutral stimulus (a previous fear) without threat. The […]
Adherence to in-person and app-based exercise for patients with hip or knee osteoarthritis; secondary analyses from a randomized controlled trial
Rheumatol Int. 2025 Aug 26;45(9):208. doi: 10.1007/s00296-025-05967-4. ABSTRACT BACKGROUND: Exercise is recommended for patients with hip/knee osteoarthritis (OA), however, adherence to exercise tends to be poor. This study aimed to (1) compare in-person versus app-based adherence to exercise therapy, (2) identify patient characteristics associated with adherence, and (3) examine associations between adherence and change in […]
Adherence Patterns of Patients Using Remote Patient Management After Myocardial Infarction: Mixed Methods Persona Approach
JMIR Cardio. 2025 Aug 18;9:e56236. doi: 10.2196/56236. ABSTRACT BACKGROUND: Remote patient management (RPM) using smartphone-enabled health monitoring devices (SHMDs) can be an effective, value-added part of cardiovascular care. However, cardiac patients’ adherence to RPM is variable. Personas are fictional representations of users with common behaviors, needs, and motivation and can thereby help guide tailoring of […]
Smartphone-Based Digital Health Interventions: A Comprehensive Systematic Review of Efficacy for Cardiovascular and Cerebrovascular Outcomes
J Med Syst. 2025 Aug 26;49(1):109. doi: 10.1007/s10916-025-02236-6. ABSTRACT Digital health interventions (DHIs) have the potential to transform the management of cardiovascular disease (CVD) and cerebrovascular disease (CeVD) by addressing their risk factors, including hypertension, diabetes, obesity, dyslipidemia, and physical inactivity. Despite this potential, there remains a need for a comprehensive understanding of their clinical […]
Development of a Theory-Based mHealth App for Fatigue Management in Lupus: Human-Centered Design Approach
JMIR Form Res. 2025 Aug 26;9:e75399. doi: 10.2196/75399. ABSTRACT BACKGROUND: Fatigue is a highly prevalent and debilitating symptom of systemic lupus erythematosus (SLE), significantly affecting the quality of life and employment of those living with the disease. Nonpharmacologic approaches, such as physical activity interventions, have shown promise in reducing fatigue but are often resource-intensive and […]
