MyCog Mobile smartphone-based cognitive screening system: a cross-sectional construct validation in a general population sample at multiple research facilities in the USA
BMJ Open. 2025 Aug 24;15(8):e092063. doi: 10.1136/bmjopen-2024-092063. ABSTRACT OBJECTIVES: Annual cognitive screening in older adults is essential for early detection of cognitive impairment, yet primary care settings face time constraints that present barriers to routine screening. MyCog Mobile is a self-administered, smartphone-based cognitive screener that has the potential to help overcome these screening obstacles. We […]
Cortical Body Maps Remain Stable After Arm Loss
This study sought to understand how the brain interprets numbers, including symbolic and non-symbolic, which helps to understand cognitive development. Earlier research indicates that humans and other animals have a non-symbolic number sense, but symbolic representations are obtained culturally and exclusive to humans only. This study used multivariate analysis and functional magnetic resonance imaging (fMRI) […]
Chromosomal Translocations Rewire Gene Expression Across Entire Chromosome Arms
Advances in chromosomal conformation capture technologies and next-generation sequencing (NGS) have revealed that mammalian genomes are structured into 3D structures like topologically associating domains (TADs), promoter-enhancer loops, chromosome territories, and nuclear compartments. Structural variations (SVs) disrupt the linear genomic continuity and reconfigure 3D nuclear design, which affects gene regulation and leads to cancer development. Initially, […]
Effects of a Multifamily App-Enhanced Cognitive-Behavioral Therapy Delivered via Telehealth for Parents of Adolescents With Mood or Psychotic Spectrum Disorders
Behav Ther. 2025 Sep;56(5):892-906. doi: 10.1016/j.beth.2025.02.002. Epub 2025 Feb 10. ABSTRACT Parents of youth with mood or psychotic disorders are affected by and also impact the course of their offspring’s psychiatric illness(es). Few studies have examined the effects of family psychotherapy on parents’ mental health in this population. This study involved a multifamily group cognitive-behavioral […]
Remote Intervention Shows Promise in Stabilizing Blood Pressure Variability
Blood pressure variability, particularly in systolic readings, is increasingly recognized as a strong predictor of cardiovascular events, stroke, dementia, kidney impairment, and all-cause mortality. The concept of variability refers not only to biological fluctuations but also to therapeutic adherence and lifestyle habits, making it a distinct clinical parameter beyond absolute blood pressure levels. Although many […]
Safety Assessment of Styrene-Based Copolymers for Cardiac Valve Applications: Six-Month Outcomes in a Juvenile Sheep Model
Approximately 1.3 million heart valve replacements were performed worldwide annually, and the number of patients was expected to rise four to five times by 2050. Nowadays, mechanical valves are durable, but they are teratogenic during pregnancy and thus patients need lifelong therapy of anticoagulants, including vitamin K antagonists. Biological valves, though biocompatible, are prone to […]
Why Stroke Center Continuing Education Is Critical for Today’s Healthcare Providers
In the U.S., every 40 seconds, a few individuals will suffer from a stroke, and this is one of the most time-sensitive emergencies in medicine. Advances such as endovascular therapy, AI-driven diagnostics, and telestroke networks are transforming outcomes, but they also demand that providers stay current with specialized training. That’s where the Annual Stroke Center […]
Characteristics Associated With the Use of the Mindfulness Meditation App Headspace in a Large Public Health Deployment: Cross-Sectional Survey Study
JMIR Form Res. 2025 Aug 22;9:e73457. doi: 10.2196/73457. ABSTRACT BACKGROUND: Mindfulness-based apps can be an effective and accessible resource for mental health support. However, little is known about their use outside of research settings and what user characteristics relate to app use. OBJECTIVE: This study aimed to examine the characteristics of people who decided to […]
Design and Evaluation of a Digital Health App (SingaporeWALK) for Active Aging: Pre-Post Intervention Study
JMIR Form Res. 2025 Aug 22;9:e68937. doi: 10.2196/68937. ABSTRACT BACKGROUND: The global trend toward population aging poses significant challenges for maintaining older adults’ health and well-being, particularly in multicultural urban environments like Singapore. Despite the potential of digital health interventions, older adults face substantial barriers to technology adoption, including complex interfaces and culturally inappropriate content. […]
From Driven Clinical Nurses to Influential Nurse Leaders: A Phenomenological Study of Millennial Nurse Leaders Experiences in Acute Care Settings
J Nurs Adm. 2025 Sep 1;55(8):479-484. doi: 10.1097/NNA.0000000000001613. ABSTRACT OBJECTIVE: This aim of this study was to understand the lived experiences of millennial-aged nurse leaders in acute care settings. BACKGROUND: As the largest generation in the nursing workforce, millennial-aged nurses are moving into nursing leadership roles as nurses of the baby boomer generation retire. The […]
