Real-World Data Uncovers How Age Influences Asthma Biologic Therapy Success
Approximately 5% of children with asthma develop severe diseases, which are associated with significantly higher morbidity and more than threefold greater healthcare costs compared to those with milder asthma. This highlights the importance of early identification as well as timely intervention. The U.S. Food and Drug Administration (FDA) has approved four biologic therapies, such as […]
Reduced-Dose Interval GLP-1 Treatment for Weight Maintenance and Metabolic Outcomes
Glucagon-like peptide-1 (GLP-1) therapies like Semaglutide and Tirzepatide have revolutionized the management of obesity and metabolic disorders, producing significant weight loss comparable to that achieved with bariatric surgery. These medications also enhance several obesity related health conditions. However, their clinical uptake is limited by high costs, restricted availability, and concerns regarding long-term treatment. Previous research […]
The effect of reminder mobile application use on medication adherence after total thyroidectomy: a randomized controlled trial
Support Care Cancer. 2026 Mar 9;34(4):295. doi: 10.1007/s00520-026-10533-0. ABSTRACT PURPOSE: This study aimed to investigate the effect of using a reminder-based mobile application on medication adherence in patients who underwent total thyroidectomy. MATERIALS AND METHODS: This randomized controlled trial followed CONSORT guidelines and included 63 patients who underwent total thyroidectomy at a university and a […]
Smartphone Use During School Hours and Association With Cognitive Control in Youths Aged 11 to 18 Years
JAMA Netw Open. 2026 Mar 2;9(3):e261092. doi: 10.1001/jamanetworkopen.2026.1092. ABSTRACT IMPORTANCE: Smartphones are a pervasive feature of adolescents’ daily lives, raising concern about how smartphones are used in contexts such as school that require sustained attention and self-regulation. OBJECTIVES: To describe youths’ smartphone use during each hour of the school day and examine whether smartphone use […]
Applying the Stimulus – Organism – Response framework for exploring use intention – a case study for a digital cultural and creative product, The Forbidden City 365 app
PLoS One. 2026 Mar 9;21(3):e0343931. doi: 10.1371/journal.pone.0343931. eCollection 2026. ABSTRACT At present, little is known about the behavioral mechanisms underlying “individuals” use of digital cultural and creative products (DCCPs). To fill this research gap, this study investigates the key determinants influencing users’ use intention, with a particular focus on how external stimuli affect users’ behavioral […]
Activity-tunable bimetallic iron-cobalt nanoflowers integrated with smartphones for rapid detection of human uric acid
Anal Chim Acta. 2026 May 1;1397:345269. doi: 10.1016/j.aca.2026.345269. Epub 2026 Feb 18. ABSTRACT BACKGROUND: Uric acid (UA), a key biomarker linked to diseases like gout and Alzheimer’s, can be detected using nanozyme technology. Developing sensitive nanozyme-based biosensors for UA is therefore crucial for early disease diagnosis and prevention. RESULTS: In this work, activity-tunable nanoflowers (FeCo […]
A novel dual-mode sensor based on green-synthesized AuNPs and natural nitrogen-doped CQDs for tobramycin detection: enhanced sensitivity and specificity
Food Res Int. 2026 Apr 30;230:118509. doi: 10.1016/j.foodres.2026.118509. Epub 2026 Jan 28. ABSTRACT A novel and environmentally sustainable dual-mode sensing platform was developed for highly sensitive and selective detection of TOB, offering a portable and visually interpretable analytical system. This approach was realized through the synthesis of nanomaterials from natural waste resources (crude beehives and […]
A Protein Engineering Approach to Replicate Oxidative Damage in γS-Crystallin
The human eye lens comprises transparent fiber cells whose nuclei and organelles are lost during development, resulting in a protein matrix mainly made of crystallins. These proteins are long-lived and must remain soluble to maintain lens transparency. Over time, crystallins undergo different post-translational modifications that can reduce solubility and cause aggregation, as lens cells cannot […]
Buying Time: Maternity Leave Policies and Critical Care Nurses’ Return to Work
Am J Crit Care. 2026 Mar 1;35(2):128-144. doi: 10.4037/ajcc2026269. ABSTRACT BACKGROUND: The nursing profession faces critical workforce shortages, intensified by high attrition linked to burnout and inadequate family supports. In the United States, maternity leave remains short and often unpaid, forcing premature returns to work that undermine health, family bonding, and career longevity. Although previous […]
Cognitive-behavioural therapy smartphone app for low mood and worry management in female armed forces veterans in Great Britain: protocol for a feasibility randomised controlled trial
BMJ Open. 2026 Mar 6;16(3):e112494. doi: 10.1136/bmjopen-2025-112494. ABSTRACT INTRODUCTION: Emotional difficulties, such as low mood and worry, are more prevalent among female forces veterans compared to their male peers. However, female veterans are more reluctant to access mental health services available for armed force veterans. To enhance help seeking, the Iona female forces veterans (IonaFFV) […]
