CYP2D6-Guided Opioid Prescribing Fails to Improve Postoperative Pain in ADOPT PGx Randomized Trial
Opioids such as tramadol, hydrocodone, and oxycodone are widely used for postoperative pain management and need metabolism by the cytochrome P450 2D6 (CYP2D6) enzyme to form their active compounds. Around 15% of individuals have reduced or absent this enzyme activity and are classified as poor or intermediate metabolizers. This can result in lower levels of […]
Rapid 4D Cardiac MRI Rendering for Integrated Valve and Myocardial Assessment
Three-dimensional (3D) imaging, specifically cardiac magnetic resonance imaging (MRI), plays a crucial role in clinical decision-making for congenital heart disease due to its ability to assess complex cardiac anatomy and function without ionizing radiation. Modern MRI generates 3D and four-dimensional (4D) datasets for dynamic visualization of cardiac activity. However, the segmentation process needed to make […]
The Impact of Digital Mental Health Apps: Effectiveness in Managing Depression and Anxiety
Stud Health Technol Inform. 2025 Oct 3;330:857-885. doi: 10.3233/SHTI251464. ABSTRACT Major Depressive Disorder (MDD) stands as a leading cause of disability, demanding innovative self-management solutions. Despite advances in treatment and management, many still struggle with daily symptoms, highlighting the urgency for solutions that can offer scalable, personalized treatment to promote long-term well-being and reduce reliance […]
Resilience in Smart Healthcare Systems
Stud Health Technol Inform. 2025 Oct 3;330:927-946. doi: 10.3233/SHTI251468. ABSTRACT The adoption of smart healthcare systems represents a significant advancement in supporting people’s health. The Internet of Things and the exponential growth of smartphones over the past decade have led to the emergence of new industries providing connected hardware and software for the smart healthcare […]
Visualization of Ex Vivo Porcine Corneal Endothelial Cells Using Smartphone-Assisted Specular Reflection With Slit-Lamp Biomicroscopy
Vet Ophthalmol. 2026 Mar;29(2):e70161. doi: 10.1111/vop.70161. ABSTRACT OBJECTIVE: To visualize corneal endothelial cells in enucleated porcine eyes using slit-lamp imaging with a mobile smartphone (SLiM), determine optimal illumination conditions, and explore agreement between SLiM and vital dye stained imaging. ANIMALS STUDIED: Twelve enucleated porcine eyes. PROCEDURES: Corneal endothelium imaging conditions of the SLiM were varied […]
Acceptability of remotely supervised Home-Based transcranial direct current stimulation combined with Cognitive-behavioural-based app for peripartum depression: perspectives from women with lived experience and mental health professionals
Sci Rep. 2026 Feb 23;16(1):5140. doi: 10.1038/s41598-026-35443-3. ABSTRACT Peripartum depression (PPD) has a global prevalence of 20% significantly impacting societies. Yet, existing treatments face barriers for its uptake. This study examined the acceptability of a remotely supervised home-based transcranial direct current stimulation (tDCS) solution combined with a CBT-based app (the FLOW Neuroscience solution) for PPD, […]
Developing a User-Centered Mobile Application Prototype: Bridging Lower-Limb Fracture Care from Skilled Nursing Facility and Back to the Community
AMIA Annu Symp Proc. 2025 May 22;2024:566-574. eCollection 2024. ABSTRACT This study is part of the OsteoPorotic fracTure preventION System (OPTIONS) project which aims to develop an evidence-based mobile application for older adults transitioning from skilled nursing facilities (SNFs) back to the community after lower limb fractures. The app promotes exercise, nutrition, and bone health […]
Unlimited Smartphone Data Plans in Older Adults With Data Deprivation: Quasi-Experimental Study
JMIR Mhealth Uhealth. 2026 Feb 23;14:e68930. doi: 10.2196/68930. ABSTRACT BACKGROUND: The growth of mobile health has underscored the critical importance of equitable internet access in promoting healthy aging. Among older adults, particularly those in digitally underserved populations, access to mobile data is often limited due to affordability and technological barriers, leading to a phenomenon known […]
Gamifying Movement: A Comprehensive Survey of Physical Activity Interventions
Stud Health Technol Inform. 2025 Oct 3;330:117-143. doi: 10.3233/SHTI251429. ABSTRACT Gamification has emerged as a powerful strategy for enhancing physical activity (PA) engagement by integrating motivational techniques and game elements into interventions. This research presents a comprehensive survey of gamified PA interventions by systematically analyzing the frequency of specific gamification elements and motivational techniques across […]
Designing Technology-Assisted Interventions for Justice-Impacted Black American Women
AMIA Annu Symp Proc. 2025 May 22;2024:854-860. eCollection 2024. ABSTRACT This study explores the challenges faced by justice-impacted Black women during their reintegration into society, with a focus on mental health care access and the potential for technology-assisted interventions to address barriers. Participants from focus groups emphasized significant obstacles, including inadequate mental health resources during […]
