Use of the ME-BYO Index, a Mobile Health App, During an Online Strength Training Program in Adults: Fidelity, Feasibility, and Acceptability Study
JMIR Hum Factors. 2025 Dec 16;12:e63123. doi: 10.2196/63123. ABSTRACT BACKGROUND: Although various apps have been developed to support health behaviors, they are mostly commercial, possibly limiting the number of users. The ME-BYO index was developed by Kanagawa Prefecture in 2019 to comprehensively and numerically measure and visualize an individual’s current health status and future disease […]
Exploring the Fit Between the Outputs of Freely Available Medication Adherence Apps and Users’ Needs: Mixed Methods Study
JMIR Mhealth Uhealth. 2025 Dec 16;13:e68919. doi: 10.2196/68919. ABSTRACT BACKGROUND: Medication nonadherence is a significant barrier to therapy success. Smartphone apps represent reasonable tools for simple adherence-enhancing interventions. Many adherence apps are available in app stores with diverse content, quality, and outputs. We define “output of an adherence app” as the processing and visualization of […]
Study on a 28-day prognostic model for ICU patients with AB infection based on machine learning
Medicine (Baltimore). 2025 Dec 12;104(50):e46459. doi: 10.1097/MD.0000000000046459. ABSTRACT This study aims to establish 28-day prognostic model for intensive care unit (ICU) patients with Acinetobacter baumannii (AB) infection based on machine learning. This retrospective study collected clinical data of patients admitted to the Intensive Care Medicine Department (ICU) of the Second Hospital of Nanjing from March […]
Zoliflodacin: A Promising Oral Therapy for Antibiotic-Resistant Gonorrhoea
The World Health Organization (WHO) estimated 82.4 million new global cases of gonorrhoea among people aged 15 to 49 years during 2020. Untreated Neisseria gonorrhoeae infection leads to substantial morbidity and enhances the risk of HIV transmission. This N. gonorrhoeae has developed resistance to all major antibiotic classes. Ceftriaxone antibiotic remains the only practical first-line […]
World’s First Human Implant of a 3D-Printed Cornea Restores Sight
Precise Bio has announced the first successful implantation in a human patient of a cornea created in a laboratory by using 3D bioprinting and cultured human eye cells. The procedure is described as a world-first breakthrough and a major step in addressing the global shortage of donor corneal tissue, which leaves millions of people waiting […]
Two Global Trials Confirm: Prediabetes Remission Lowers Heart Disease Risks
Prediabetes is associated with increased risk of early mortality and cardiac diseases, as well as heart failure. Insulin resistance plays a major role in these risks. Lifestyle modifications can prevent type 2 diabetes and improve cholesterol and blood pressure. However, long-term studies have not shown benefits for the prevention of major death or heart problems. […]
FDA Approves CARDAMYST™: A First-of-Its-Kind Nasal Spray for Adult PSVT Patients
The U.S. Food and Drug Administration (FDA) has approved CARDAMYST™ (etripamil) nasal spray as the first and only self-administered therapy for adults experiencing acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT). Announced on December 12, 2025, this landmark decision addresses an unmet need for more than two million Americans living with PSVT, who had not […]
A Refined Mobile Health Intervention (SMARTFAMILY2.0) to Promote Physical Activity and Healthy Eating in a Family Setting: Randomized Controlled Trial
JMIR Mhealth Uhealth. 2025 Dec 15;13:e65558. doi: 10.2196/65558. ABSTRACT BACKGROUND: Many mobile health (mHealth) apps focus on promoting physical activity (PA) and healthy eating (HE). However, there is limited empirical evidence regarding their effectiveness in initiating and sustaining behavior change, particularly among children and adolescents. Considering that behavior is influenced by social contexts, it is […]
Early prediction of vasopressor initiation in ICU sepsis patients using an interpretable EHR-based ML model
BMC Med Inform Decis Mak. 2025 Dec 15;25(1):442. doi: 10.1186/s12911-025-03274-3. ABSTRACT BACKGROUND: Early identification of septic patients who will require vasopressor support could provide a critical window for hemodynamic optimisation, yet current bedside cues often appear only when shock is imminent. OBJECTIVE: We aimed to develop and validate an interpretable electronic health record (EHR)-based machine-learning […]
Smartphone App-Based Eating Behavior Monitoring and Feedback Intervention for Glucocorticoid-Induced Appetite Increase in Patients With Systemic Lupus Erythematosus: Protocol for a Pilot Randomized Controlled Trial
JMIR Res Protoc. 2025 Dec 15;14:e78612. doi: 10.2196/78612. ABSTRACT BACKGROUND: Increased appetite and weight gain are common adverse effects of glucocorticoid therapy in patients with systemic lupus erythematosus (SLE). Concerns about appearance-related changes due to weight gain can reduce medication adherence. Moreover, the complex interplay among glucocorticoids, mood changes, sleep disturbances, and appetite can influence […]
