The Impact of a Digital Peer-Supported App on Daily Steps and Lifestyle Changes Among Individuals With Prediabetes and Early-Stage Type 2 Diabetes: Prospective, Nonrandomized Controlled Trial
JMIR Form Res. 2025 Dec 15;9:e75953. doi: 10.2196/75953. ABSTRACT BACKGROUND: Physical activity is a simple, low-risk intervention that could be integrated into daily life to improve glycemic control in individuals with prediabetes and early-stage type 2 diabetes mellitus (T2DM). However, maintaining physical activity remains challenging, even when its benefits are well understood. Although digital peer […]
A Refined Mobile Health Intervention (SMARTFAMILY2.0) to Promote Physical Activity and Healthy Eating in a Family Setting: Randomized Controlled Trial
JMIR Mhealth Uhealth. 2025 Dec 15;13:e65558. doi: 10.2196/65558. ABSTRACT BACKGROUND: Many mobile health (mHealth) apps focus on promoting physical activity (PA) and healthy eating (HE). However, there is limited empirical evidence regarding their effectiveness in initiating and sustaining behavior change, particularly among children and adolescents. Considering that behavior is influenced by social contexts, it is […]
Overcoming Workplace Struggles: The Mediating Role of Trauma-Informed Climate on Psychological Well-Being, Emotional Resilience and Job Performance Among Critical Care Nurses
Nurs Crit Care. 2026 Jan;31(1):e70218. doi: 10.1111/nicc.70218. ABSTRACT BACKGROUND: Critical care nurses face persistent high-stress conditions that can compromise their mental health and job performance. In response, there is growing recognition of the value of a Trauma-Informed Climate (TIC), which provides a framework that promotes psychological safety by acknowledging the impact of trauma and fostering […]
Beyond Traditional Models-The Impact of Machine Learning on Intensive Care Unit Outcome Predictions: A Narrative Review
J Assoc Physicians India. 2025 Dec;73(12):84-88. doi: 10.59556/japi.73.1260. ABSTRACT Accurate prediction of patient outcomes in intensive care units (ICUs) is crucial for enhancing clinical decision-making, patient care, and resource allocation. Traditional scoring systems like Acute Physiology and Chronic Health Evaluation (APACHE), Simplified Acute Physiology Score (SAPS), and Sequential Organ Failure Assessment (SOFA), while valuable, fall […]
Genomic Study Maps Shared Risk Factors for 14 Psychiatric Disorders
Approximately half of all people experience at least one psychiatric disorder in their lifetime, and many develop multiple conditions, which makes diagnosis difficult. These disorders are defined by symptoms rather than clear biological mechanisms, which creates further challenges in distinguishing them. Genomic research has identified hundreds of associated genetic loci. Many of these are shared […]
Effects of smartphone use duration on postural balance in adolescents with intellectual disabilities
BMC Pediatr. 2025 Dec 11;25(1):983. doi: 10.1186/s12887-025-06277-1. ABSTRACT BACKGROUND: This study investigates the impact of different smartphone use durations on postural balance in adolescents with moderate to mild intellectual disabilities. METHODS: Twenty-two participants, aged 10 to 16 years, engaged in smartphone use sessions lasting 10, 20, and 40 min. Postural balance was assessed before, immediately […]
ADHD remote technology and ADHD transition: predicting and preventing negative outcomes (ART-transition) – an adolescent prospective cohort study protocol
BMC Psychiatry. 2025 Dec 11;25(1):1146. doi: 10.1186/s12888-025-07546-0. ABSTRACT BACKGROUND: Late adolescence is a highly challenging and potentially critical period for young people with attention deficit hyperactivity disorder (ADHD). Many of the conditions that frequently co-occur with ADHD, such as depression, often first emerge in adolescence. Major life transitions, such as moving out of the parental […]
Gepotidacin Gains FDA Priority Review for Breakthrough Oral Gonorrhea Therapy
The US Food and Drug Administration (FDA) has received a supplemental New Drug Application for gepotidacin requesting priority review. The application is requesting to approve gepotidacin as an orally administered therapy of uncomplicated urogenital gonorrhea in patients aged 12 years and above with a weight of at least 45 kg. The FDA action date under […]
Development of Disease Activity Assessment Criteria in AOSD: EULAR Points to Consider
Adult-onset Still’s disease (AOSD) is a rare systemic autoinflammatory disorder that can lead to symptoms like fever, arthritis, and hyperferritinaemia. It is seen as an adult form of systemic juvenile idiopathic arthritis (SJIA). Treatment options such as glucocorticoids and biologic DMARDs are available, but there are no standardized criteria for assessing disease activity. Current studies […]
Northeastern U.S. Children Show Signs of Worse Asthma in Wildfire Smoke
Climate change is affecting human health through more extreme weather, worsening chronic conditions, higher temperatures, malnutrition, biodiversity loss, and the spread of diseases. Wildfire smoke is a growing concern as wildfire seasons increase, especially in the United States. Children and people with respiratory disease are more at risk from smoke exposure. Pediatric asthma affects more […]
