Groundbreaking Study Highlights Benefits of Early Pregnancy Scans in Detecting Fetal Anomalies

Congenital anomalies affect 2-3% of newborns and are major contributors to morbidity and mortality. The routine second-trimester (20-week) ultrasound scan is the main current standard screening tool and detects about two-thirds of these cases. Most fetal organogenesis is completed by 10 weeks, and advances in high-resolution imaging now allow earlier anatomical assessment during pregnancy. Many […]

Effectiveness of a smartphone-delivered Approach-Avoidance intervention in dietary behavior – a randomized controlled trial

Int J Behav Nutr Phys Act. 2025 Nov 28;22(1):153. doi: 10.1186/s12966-025-01836-2. ABSTRACT BACKGROUND: Given the therapeutic potential of Approach-Avoidance interventions (AAIs) in the alcohol domain, research has increasingly applied them to the food domain. In AAIs, harmful stimuli are avoided while healthy ones are approached, for example by respectively moving a phone away from or […]

Feasibility and evaluation of a digital preventive physiotherapy protocol for workers: A randomized clinical trial

J Bodyw Mov Ther. 2025 Dec;45:991-998. doi: 10.1016/j.jbmt.2025.09.032. Epub 2025 Oct 15. ABSTRACT Preventive physiotherapy plays an essential role in health promotion, emphasizing educational strategies and interventions aimed at preventing musculoskeletal dysfunctions. This study aimed to investigate the effects of a preventive physiotherapy protocol mediated by a mobile application on the health of workers. The […]

Antimicrobial Effects of Agricultural and Industrial Chemicals on Human Gut Microbiota

Environmental contamination from synthetic chemicals like pesticides, industrial pollutants, and persistent organic compounds has increased significantly in recent decades. This rise has raised concerns about their largely overlooked impact on the human gut microbiome. Although many of these chemicals are not designed to target bacteria, they routinely reach the gastrointestinal (GI) tract through water, food, […]

ADHD Treatments Under the Spotlight: Weighing Benefits and Harms

Attention deficit/hyperactivity disorder (ADHD) is characterized by persistent and impairing inattention, hyperactivity, impulsivity, or a combination of these symptoms. It is estimated to occur in 5% of children, and symptoms persist into adulthood in up to 70% of cases. ADHD frequently co-occurs with mood disorders, anxiety disorders, substance use disorders, and impairments, including emotional dysregulation […]

WAYFINDER Results Highlight Tezepelumab’s Impact on Steroid-Dependent Asthma

Reducing or eliminating the use of oral corticosteroids (OCS) is a key goal in managing severe asthma due to the significant adverse events associated with long-term OCS use. Biologic therapies targeting thymic stromal lymphopoietin (TSLP), interleukin-4/13 (IL-4/13), interleukin-5 receptor (IL-5R), and interleukin-5 (IL-5) can improve lung function, lower the OCS dependence, and reduce exacerbation rates. […]

Effectiveness of Mobile-Based Cognitive Behavioural Therapy for Depression and Anxiety in Children and Young People: A Systematic Review of Randomized Controlled Trials

Clin Psychol Psychother. 2025 Nov-Dec;32(6):e70173. doi: 10.1002/cpp.70173. ABSTRACT Mobile-based cognitive behavioural therapy (CBT) has emerged as a promising digital intervention for depression and anxiety in children and young people. This systematic review aimed to evaluate the effectiveness and feasibility of mobile-based CBT for this population. We conducted a systematic search across six electronic databases for […]

Developing an Omaha System-based health application to improve knowledge, attitude, and behaviors regarding infectious disease prevention in the community: a study protocol for a randomized controlled trial

BMC Public Health. 2025 Nov 27;25(1):4170. doi: 10.1186/s12889-025-25587-8. ABSTRACT BACKGROUND: Infectious diseases remain significant public health concerns due to several factors such as climate and environmental changes and natural disasters. Mobile health applications (mHealth apps) can be an appropriate way for fostering community participation, disseminating knowledge, and promoting behavior change toward infectious disease prevention. This […]

Clinical Efficacy of Smartphone App-Based Pulmonary Rehabilitation in Chronic Respiratory Diseases: Randomized Controlled and Feasibility Trials

J Med Internet Res. 2025 Nov 28;27:e76801. doi: 10.2196/76801. ABSTRACT BACKGROUND: Pulmonary rehabilitation improves exercise capacity, dyspnea symptoms, quality of life, and even survival in patients with chronic respiratory disease. Center-based pulmonary rehabilitation programs often face barriers, and alternatives to center-based rehabilitation are urgently needed. OBJECTIVE: This study aimed to evaluate the clinical efficacy of […]

A Messaging App Empowering Lifestyle Modification in Chronic Kidney Disease (LINE Official Account “Kidney Lifestyle”): Platform Development and Usability Study

JMIR Hum Factors. 2025 Nov 26;12:e73935. doi: 10.2196/73935. ABSTRACT BACKGROUND: Regular lifestyle modification is crucial for chronic kidney disease (CKD) management; yet, older patients often struggle to sustain behavior change and rely on support from their significant others such as family caregivers or partners. In such cases, both members of the dyad require accessible, jointly […]

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