Research in Brief: Mobile Applications to Promote Sun Protective Behaviors in Adolescents
Pediatr Dermatol. 2025 Nov-Dec;42(6):1194-1197. doi: 10.1111/pde.16035. Epub 2025 Jul 18. ABSTRACT Mobile app-based interventions, especially photoaging technologies for sun protective behaviors, are new and promising tools. We conducted a review of published studies to date that evaluate such mobile apps used in pediatric populations, and our analysis highlights short-term improvements in sun-protective behaviors, with over […]
A Game-Changer for Diabetes: Polymer Delivers Insulin Painlessly Through Skin
Transdermal delivery of biomacromolecules offers a convenient route for drug administration. This delivery avoids first-pass metabolism but remains challenging due to the skin barrier structure, including tight junctions and hydrophobic stratum corneum. Insulin still requires subcutaneous injections, which cause compliance and discomfort issues, whereas non-invasive approaches remain unsuccessful. Existing enhancement strategies like electrical devices, jet […]
From Stress to Symphony: Music Helps Patients Need Less Propofol in Laparoscopic Surgery
Pharmacological agents used to achieve general anaesthesia in laparoscopic surgery are usually associated with hemodynamic instability, delayed recovery, and postoperative nausea. Non-pharmacological adjuncts like music therapy have demonstrated potential in reducing perioperative stress, regulating autonomic responses, and decreasing anaesthetic needs. Studies suggest that auditory pathways might not be entirely inactivated during anaesthesia, which means that […]
DMT Alters Neural Criticality and Predicts the Intensity of Ego Dissolution
Classic psychedelics like N, N-Dimethyltryptamine (DMT) have a tremendous effect on perception, cognition, and self-experience. Recent studies suggest that these substances can reveal fundamental principles of brain function. According to one theoretical framework, the brain generally operates near critically an optimal balance between order and disorder that supports long-range temporal correlations (LRTC), efficient information processing, […]
The Brain’s Blueprint for Universal and Native Language Processing
A landmark study published in Nature in 2025 revealed how the human brain processes speech in both native and non-native languages, uncovering a clear distinction between universal mechanisms and those shaped by linguistic experience. Researchers recorded high-density electrocorticography activity in adult Spanish, English, and Mandarin speakers as they listened to sentences in both their native […]
Shifting Cost–Benefit Appraisals: A Short Intervention for Procrastination
Procrastination is a common and maladaptive behavior characterized by the irrational delay of intended tasks, typically arising from a momentary imbalance between the perceived value of task completion and the emotional discomfort associated with performing it. The current study applied the Temporal Decision Model, which frames procrastination as a cost-benefit evaluation sensitive to emotional states […]
Interpretable Machine Learning Models for Analyzing Determinants Affecting the Use of mHealth Apps Among Family Caregivers of Patients With Stroke in Chinese Communities: Cross-Sectional Survey Study
JMIR Mhealth Uhealth. 2025 Nov 24;13:e73903. doi: 10.2196/73903. ABSTRACT BACKGROUND: Mobile health (mHealth) apps are believed to be an effective method to support family caregivers to better care for patients with stroke. This study’s purpose was to explore the status and the influencing factors of mHealth app use among family caregivers of patients with stroke […]
A Flash of Recovery: Temporary Eye Inactivation Restores Lost Vision Pathways
Amblyopia is a loss of vision in one eye caused by inadequate binocular experience. The standard treatments, like patching, are effective only during a critical developmental period. However, it’s difficult to recover from this vision loss in adulthood. Hence, researchers conducted animal studies showing that temporary retinal inactivation with tetrodotoxin (TTX) can reverse long-term monocular […]
Advanced Cardiovascular Life Support simulated practice in nursing: A prospective cohort study
Enferm Intensiva (Engl Ed). 2025 Oct-Dec;36(4):500567. doi: 10.1016/j.enfie.2025.500567. ABSTRACT BACKGROUND: Simulation is a pedagogical methodology that promotes the development of technical, scientific, communicational, relational, and leadership skills without compromising people’s safety. This study aimed to analyze the association between Advanced Cardiovascular Life Support simulation practice and Internal Medical Emergency Teams nurses’ self-perceived competence and assess […]
Koselugo Becomes First Approved Therapy for Adult NF1 Patients in the U.S.
The U.S. Food and Drug Administration (FDA) has approved the Koselugo (selumetinib), an oral MEK inhibitor, for the treatment of adults with neurofibromatosis type 1 (NF1) and symptomatic, inoperable plexiform neurofibromas (PN). It is manufactured by Alexion, which is a part of AstraZeneca Rare Disease. NF1 is a progressive, rare, and genetic disorder. It is […]
