A Step Toward Remission: FDA Approves CAPLYTA® for Major Depressive Disorder
Major depressive disorder (MDD) is the most prevalent psychiatric disorder, affecting 22 million adults in the United States. Depression is often treated uniformly, yet MDD is highly complex, affecting various brain regions and presenting in diverse symptom patterns, leading to widely different treatment responses. Although several antidepressant medications are available, two out of three individuals […]
Stem Cell Patch to Heal Damaged Hearts
Researchers have found a new way to fix damaged hearts that doesn’t involve open-heart surgery. This could transform the treatment approach for heart failure in the future. The development includes a piece of heart tissue that has been repaired by adult stem cells that have been reprogrammed. In preclinical trials, this stem cell patch made […]
From Cancer Marker to Healer: The Regenerative Role of SerpinB3
SerpinB3 or squamous cell carcinoma antigen (SCCA-1) is a serine protease inhibitor and clinical biomarker for epithelial cancers, such as those affecting the head and lung, neck, skin, and liver. Increased levels of SerpinB3 can lead to tumor progression, metastasis, and poor prognosis. Traditionally linked cancer-promoting processes like immune evasion and apoptosis resistance have a […]
One Cup of Coffee a Day Keeps AF Away? Insights from the DECAF Trial
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. It is affecting more than 10.5 million Americans and up to one in three globally during their lifetime. Identifying modifiable risk factors is crucial to reducing AF burden. Coffee is a widely consumed beverage in the U.S. and is rich in caffeine. Coffee has traditionally been […]
Mind-Body Healing Retreat Found to Rewire Brain and Boost Molecular Pathways
A recently published article in Communications Biology reported significant neural and molecular changes following a seven-day mind-body retreat that included meditation, cognitive reconceptualization, and open-label placebo exercises. Researchers at the University of California, San Diego, conducted a study of the impact that intensive, non-pharmacological interventions have on the brain activity, neuroplasticity, and metabolic functioning of healthy […]
What each International Medical graduate (IMG) should know about obtaining a US medical license
It is an important step for international medical graduates (IMGs) to get a US medical license to practice medicine in the U.S. It is essential to understand the licensing process for IMGs’ career planning and navigating the challenges that come with American medical standards. IMGs may face challenges such as exam preparation, complex documentation, and […]
Association between cognitive function and smartphone ownership among Japanese very old adults: a cross-sectional and longitudinal study
BMC Geriatr. 2025 Nov 7;25(1):866. doi: 10.1186/s12877-025-06561-w. ABSTRACT BACKGROUND: This research was conducted to investigate the association between cognitive function and smartphone ownership among very old adults, a rapidly growing age group. Additionally, we conducted a longitudinal investigation as a sub-analysis to determine whether owning a smartphone affects the level of long-term care certification as […]
Association Between Patient-Physician Distance and Primary Care Access in Ontario: A Population-Based Cross-Sectional Study
Access to primary care is important in Canada. Approximately 2.3 million Ontarians lack access to a regular source of public funding through the Ontario Health Insurance Plan (OHIP). Ontario’s primary care has shifted to patient enrolment models, with 75% of the population assigned to family physicians. Geographic distance poses challenges, as many patients have links […]
New FDA Approval Marks Breakthrough for High-Risk Smoldering Myeloma Patients
The U.S. Food and Drug Administration (FDA) has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj, Janssen Biotech, Inc.) to treat adults with high-risk smoldering multiple myeloma (SMM). This is the first FDA approval for this category of patients at high risk of developing active multiple myeloma. This was supported by the results of AQUILA (NCT03301220), an open-label study that […]
Mobile health education for salt reduction and hypertension prevention: effects on knowledge acquisition and behavioral change among Chinese third-grade students
Front Public Health. 2025 Oct 22;13:1600342. doi: 10.3389/fpubh.2025.1600342. eCollection 2025. ABSTRACT BACKGROUND AND AIMS: This study evaluates the impact of a comprehensive health education intervention delivered via a mobile application on health knowledge and behavior among third-grade students in Zhenjiang, Jiangsu Province, China. With increasing rates of non-communicable diseases, particularly hypertension among children, this intervention […]
