Mind-Body Healing Retreat Found to Rewire Brain and Boost Molecular Pathways

A recently published article in Communications Biology reported significant neural and molecular changes following a seven-day mind-body retreat that included meditation, cognitive reconceptualization, and open-label placebo exercises. Researchers at the University of California, San Diego, conducted a study of the impact that intensive, non-pharmacological interventions have on the brain activity, neuroplasticity, and metabolic functioning of healthy […]

Association between cognitive function and smartphone ownership among Japanese very old adults: a cross-sectional and longitudinal study

BMC Geriatr. 2025 Nov 7;25(1):866. doi: 10.1186/s12877-025-06561-w. ABSTRACT BACKGROUND: This research was conducted to investigate the association between cognitive function and smartphone ownership among very old adults, a rapidly growing age group. Additionally, we conducted a longitudinal investigation as a sub-analysis to determine whether owning a smartphone affects the level of long-term care certification as […]

Association Between Patient-Physician Distance and Primary Care Access in Ontario: A Population-Based Cross-Sectional Study

Access to primary care is important in Canada. Approximately 2.3 million Ontarians lack access to a regular source of public funding through the Ontario Health Insurance Plan (OHIP). Ontario’s primary care has shifted to patient enrolment models, with 75% of the population assigned to family physicians. Geographic distance poses challenges, as many patients have links […]

New FDA Approval Marks Breakthrough for High-Risk Smoldering Myeloma Patients

The U.S. Food and Drug Administration (FDA) has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj, Janssen Biotech, Inc.) to treat adults with high-risk smoldering multiple myeloma (SMM). This is the first FDA approval for this category of patients at high risk of developing active multiple myeloma. This was supported by the results of AQUILA (NCT03301220), an open-label study that […]

Usability and User Experience of a Digital Platform Prototype (Healthy Bone) to Promote Pharmacological and Nonpharmacological Treatment in Patients With Osteoporosis: Mixed Methods Study

JMIR Form Res. 2025 Nov 7;9:e72468. doi: 10.2196/72468. ABSTRACT BACKGROUND: Osteoporosis-related fractures significantly impact older adults, often leading to disability and even premature death. While pharmacological and nonpharmacological interventions are widely recommended for managing osteoporosis, adherence to these interventions remains low. To address this challenge, we developed the Healthy Bone digital platform (desktop, mobile app, […]

Enablers, Challenges, and Lessons Learned From a Digital Health Intervention (Sehatmandi App) in Afghanistan: Qualitative Study

J Med Internet Res. 2025 Nov 7;27:e74923. doi: 10.2196/74923. ABSTRACT BACKGROUND: In low- and middle-income countries, maternal, newborn, and child health face significant challenges due to infrastructure limitations, access disparities, and service delivery inefficiencies. The Sehatmandi mobile health (mHealth) app was deployed in 2018 to address these issues across 189 health facilities in Afghanistan’s Bamyan […]

Mobile health education for salt reduction and hypertension prevention: effects on knowledge acquisition and behavioral change among Chinese third-grade students

Front Public Health. 2025 Oct 22;13:1600342. doi: 10.3389/fpubh.2025.1600342. eCollection 2025. ABSTRACT BACKGROUND AND AIMS: This study evaluates the impact of a comprehensive health education intervention delivered via a mobile application on health knowledge and behavior among third-grade students in Zhenjiang, Jiangsu Province, China. With increasing rates of non-communicable diseases, particularly hypertension among children, this intervention […]

A novel mobile application to examine impaired vigilance through digital means

Sci Rep. 2025 Nov 7;15(1):39115. doi: 10.1038/s41598-025-23155-z. ABSTRACT The psychomotor vigilance task (PVT) is a three to thirty-minute test widely used to measure alertness and vigilance. However, only a few comprehensively validated PVTs are currently available through digital means, e.g., mobile devices. Thus, the present study aimed to investigate the usefulness of a novel three-minute […]

Knowledge transfer-driven estimation of knee moments and ground reaction forces from smartphone videos via temporal-spatial modeling of augmented joint kinematics

PLoS One. 2025 Nov 7;20(11):e0335257. doi: 10.1371/journal.pone.0335257. eCollection 2025. ABSTRACT The knee adduction and flexion moment provides critical information about knee joint health, while 3D ground reaction forces (GRFs) help identify force and energy characteristics for maneuvering the entire human body. Existing methods of acquiring joint moments and GRFs require expensive equipment, time-consuming pre-processing, and […]

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