A study published in Nature Medicine the author identified a new connection between lipid biomarker and metabolic disorder which can be helpful in early diagnosis of liver diseases.
Addressing the same cross-sectional study on chilly extension, speculating that utilizing existing machines in the hospital to test the blood plasma of babies will assist the doctors to identify the first indications of the condition of the kid and facilitate him or her to gain the appropriate treatment.
The findings also contradict the notion that cholesterol is the major agent connected with complications surrounding obesity in children, revealing new lipid regulatory particles connected with other health risks as well, including blood pressure but not necessarily weight.
They were considered as ordinary fatty acids in the body or good or bad cholesterol or triglycerides which are fats that circulate in the bloodstream and are the most abundant fats in the human body.
With the help of the team, taking a control sample with 1300 children having obesity, the blood lipids were measured. Subsequently, 200 of the patients were placed on the HOLBAEK-model for a year, which is a type of lifestyle modification programme in the management of obesity prevalent in Denmark.
Further reading revealed that the counts of lipids associated with diabetes risks, insulin resistance and blood pressure were reduced among the interventional group though the BMI of the children did not receive a boost in many cases.
The principal author Dr. Cristina Legido-Quigley, a group leader in Systems Medicine at King’s College London, and the Head of Systems Medicine at the Steno Diabetes Centre Copenhagen (SDCC), said: ‘For several years, it has been considered acceptable to categories lipids as the ‘good’ high-density lipoprotein cholesterol and ‘bad’ low-density lipoprotein cholesterol, while now, using a blood test, one It has the potential that in the future this can be the thought of as an entirely new method of assessing someone’s individual risk of contracting a disease and by learning how to manipulate lipid particles in the body we could possibly fully eradicate diseases like diabetes.
While obesity remains as an RR for diseases such as fatty liver disease, the team hopes that physicians will employ these measures to treat children when they are only a bit larger than other kids at risk.
Dr. Karolina Sulek, who participated in the study and conducted the analysis at the SDCC, pointed out that, “Early identification of children at risk of these severe diseases is important.”
Subsequently, the findings presented in the paper show that the next steps for the researchers are geared towards learning how genetic factors can influence lipids and its consequences on metabolic diseases, and how those lipids can be modified to enhance health among individuals.
Reference:
1.King’s College London. New blood test could be an early warning for diabetes in children
Nature Medicine (2024). DOI: 10.1038/s41591-024-03279
