Hyperemesis gravidarum is a severe form of nausea and vomiting that occurs during pregnancy period. 

This pregnancy-related condition occurs due to severe nausea, vomiting, and electrolyte disturbance in the female. It is generally observed in the first trimester. 

It is a rare form of nausea and vomiting which affects 0.3% to 2.0% of pregnancy cases globally and it is a less common issue compared to milder forms. 

Hyperemesis gravidarum is more prevalent in westernized societies and urban areas. 

Hyperemesis gravidarum in women results in transient hyperthyroidism due to high hCG levels and inadequate food quality and improper fluid intake can cause metabolic imbalances and nutritional deficiencies in some pregnant women. 

Pregnancies with female fetus, low to middle economic class, and lower education levels all have higher chance of occurring this condition. 

Symptoms of pregnancy, in the first trimester which lead to a longer duration of illness in women. 

Women with pre-existing medical conditions may experience a lower prognosis. 

Hyperemesis Gravidarum affect pregnant women across different age groups. 

• Abdominal Examination 
• Assessment of Hydration Status 
• Neurological Examination 
• Assessment of Fetal 

The woman may sometimes experience rapid increase of symptoms which causes significant distress and functional impairment. 

Nutritional supplements play an important role in management of Hyperemesis Gravidarum. Women should consume more amount of food which has dietary nutrients.  

It is very necessary to avoid dehydration along with electrolyte imbalances in pregnant women. Always maintain proper hydration or fluids intake level on higher side.  

Women with nutritional deficiencies need to take more vitamins and minerals in form of oral intake. 

OB/GYN and Women\'s Health

More rest should be taken by women in such condition to relax body and to stable mentally.  

The proper ventilation and good flow of air should be there around women all the time to keep air quality dusts free. 

Schedule the day with regular intake of food, supplements and drinks that will give energy and help to stay active. 

OB/GYN and Women\'s Health

Ondansetron: It is a selective serotonin receptor antagonist widely used to control nausea and vomiting. 

OB/GYN and Women\'s Health

Methylprednisolone: It has anti-inflammatory and antiemetic properties, which help to reduce the feeling of nausea and vomiting.  

OB/GYN and Women\'s Health

Pyridoxine: It consists of vitamin B6 supplements which help to reduce symptoms of nausea and vomiting in pregnancy.  

It is used in combination with doxylamine as a first-line treatment. 

OB/GYN and Women\'s Health

Meclizine: It reduces the excitability of the middle ear labyrinth and blocks conduction in the vestibular-cerebellar pathways. 

OB/GYN and Women\'s Health

Nutrition should provide required nutrients and supplements to manage nutritional deficiencies and then dieticians should give therapies including vitamins and minerals which avoid the feeling of nausea or vomiting.  

OB/GYN and Women\'s Health

Gynecologists should check as part of initial assessment including medical history, conduct physical examination, and review laboratory test results to assess the severity of patient’s condition.  

Preventive measures should be taken including dietary modification with proper medicines to give relief from discomfort and nutrition and dietitians play a major role in giving these therapies under their observation.  

The regular follow-up visits with the Gynecologist are required to check the improvement of patients and treatment response.