Majocchi Granuloma is a rare fungal infection of deep follicles which it is caused by dermatophyte fungi, and it presents in erythematous papules, nodules and localized to hair-bearing areas.  

It may be mistaken for other dermatological conditions which lead to misdiagnosis and delayed treatment. 

Majocchi Granuloma Prevalence is more seen in individuals with compromised immune systems, organ transplant recipients and receiving immunosuppressive therapy.  

The higher prevalence in women with predisposing factors is observed in study. 

Dermatophyte fungi enters skin through minor trauma, shaving, and compromised skin barrier.  

The proliferate and invade surrounding of hair follicles and predilection for keratinized tissues like hair shafts, nails, and stratum corneum and it invade hair shaft and extend into follicular epithelium within hair follicles. 

Majocchi Granuloma risk factors develops after skin trauma or injury.
The individuals with compromised immune systems, including diabetes patients and immunosuppressive therapy patients are at higher risk. 

Predisposing factors in treatment of diabetes or peripheral vascular disease increases risk of complications and delayed wound healing.
The prognosis influenced by skin involvement and infection spread and it adhere to antifungal therapy and follow-up is necessary for successful treatment. 

Majocchi granuloma can mostly affect adults and it is more frequently observed in adolescents and in young to middle-aged individuals.  

• Peripheral findings
• Systemic examination
• Nail examination
• Scalp examination

Symptoms of Fungal Infections include itching, pain, or tenderness and initial appearance of small papules or nodules.  

The chronic cases more common in immunocompromised individuals or those with underlying conditions. 

Antifungal drug therapy is the main treatment given to patients of Majocchi granuloma. 

Supportive measures such as wound care, gentle cleansing and application of emollients on skin are considered to prevent secondary bacterial infections. 

Follow up studies and evaluation for clinical status are required. Appointments with medical physicians and preventing recurrence of infection is an ongoing life-long effort. 

Dermatology, General

Patient should start regular bathing with soap and water as good hygiene practice and aggressive shaving and waxing on skin should be avoided.  

Patient should never share their personal items such as towels, undergarments, and grooming tools with others.  

Always wear suitable footwear in crowdy areas also in areas where the risk of fungal exposure is high. 

Dermatology, General

Terbinafine inhibits squalene epoxidase enzyme which can disrupt fungal cell membrane integrity. 

Butenafine is a synthetic benzylamine agent which leads to fungal cell death. 

Clotrimazole inhibits ergosterol synthesis which can disrupt membrane function. 

Dermatology, General

Incision and drainage may be indicated to alleviate pain and reduce inflammation in cases where lesions have become fluctuant in nature.  

Surgical debridement procedure is used in cases of extensive and necrotic lesions which help to remove devitalized tissue, reduce bacteria and facilitate the healing process. 

In cryotherapy procedure involves the use of extreme cold to the skin lesions using liquid nitrogen and other cryogenic agents.  

Dermatology, General

The initial diagnosis phase involves evaluation of patient’s history, physical examination, and diagnostic tests. 

After the confirmation diagnosis, the acute treatment phase starts with use of systemic antifungal therapy to deal with the underlying fungal infection.  

In acute treatment phase, the physician should monitor the patient very closely to assess the effectiveness of treatment and ensure daily progress.