Mucous Membrane Anesthesia

Updated: January 30, 2023

Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

cocaine

Recommended as a local (topical) anaesthetic for the oral, nasal, and laryngeal cavities exposed mucous membranes:

Use the lowest dose required to generate sufficient anaesthesia when using a 1–10% solution
Never go beyond 3 mg/kg or 300 mg

prilocaine/epinephrine

Administer initial dose of 40 to 80 mg
Administer maximum dose on weight basis within 2-hours
for ≥70 kg: dose of 400 mg
for <70 kg: dose of 6 mg/kg

prilocaine/epinephrine

For <10 years old:
Dose of >40 mg of prilocaine as a 4% solution with epinephrine 1:200,000 are rarely required for procedures involving a single tooth, in a maxillary infiltration process for 2 to 3 teeth
For >10 years old:
Administer initial dose of 40 to 80 mg
Administer maximum dose on weight basis within 2-hours

Future Trends