Myopia

Updated: December 25, 2024

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Background

Myopia causes blurred distance vision while close vision remains clear. It allows clear vision of nearby objects but causes difficulty with distant ones.

Myopia is the medical term for near-sightedness. It includes simple myopia and pathologic myopia.

Simple myopia can be corrected with glasses or lenses, but pathologic myopia may not achieve clear vision even with correction.

Myopia can be inherited and developed through lifestyle choices. Individual can read maps but struggle with driving due to vision.

Close-up tasks like reading or using computers can lead to myopia development. When the eyeball is elongated or the cornea is overly curved, light entering the eye misfocusess.

Myopia types as follows:

Simple/school myopia

Degenerative/malignant myopia

Epidemiology

Myopia affects many worldwide, especially in East Asia, where over 80% of young adults are impacted.

It develops in childhood and progresses through adolescence. The rate of progression slows in adulthood.

Myopia is increasingly prevalent globally and, in the U.S., yet limited domestic research exists due to inconsistent definitions.

An estimated 50% of the global population are projected to be myopic by 2050 with nearly 10% at risk of high myopia.

Anatomy

Pathophysiology

Lung axial length relative to optical power causes excessive refractive power in the cornea/lens to light focusing in front of the retina.

Excessive curvature of cornea or lens enhances eye refractive power.

A hypothesis posits that peripheral light focusing behind the retina signals the eye to elongate through retinal signalling pathways.

The retina detects signals, and dopamine prevents excessive elongation through biochemical pathways.

The choroid thins in myopic eyes while near-work activities and low outdoor light contribute to myopia progression.

Etiology

The causes of myopia are:

Genetic Factors

Environmental Factors

Optical Factors

Lifestyle and Behavioral Factors

Genetics

Prognostic Factors

Earlier onset of myopia increases risk of rapid progression and severity in adulthood during growth years.

Children are more likely to develop myopia if one or both parents are myopic.

Higher initial refractive error leads to faster progression, while mild myopia in adults progresses less.

Prolonged near work without breaks accelerates myopia progression significantly.

Clinical History

Collect details including presenting symptoms, vision and medical history to understand clinical history of patient.

Physical Examination

Visual Acuity Testing

Pupil Examination

External Eye Examination

Slit Lamp Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Blurred distance vision, difficulty reading or seeing details, asthenopia, and night vision problems.

Differential Diagnoses

Hyperopia

Astigmatism

Anisometropia

Amblyopia

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

Glasses have been used for centuries to correct/improve blurry distance vision. The concave lens is thinnest in the middle that allows parallel light rays.

Plastic lenses are favoured for their lightweight properties, and polycarbonate lenses protect children’s eyes.

The traditional lens design for myopia blur treatment is single-vision unlike bifocals with two or progressive-addition lenses with gradual power increase.

Rigid gas permeable lenses are hard plastic contact lenses that correct myopic blur and are worn directly on the cornea.

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

use-of-non-pharmacological-approach-for-myopia

Natural light regulates eye growth and decreases near activity time.

Promote reading by windows and minimize artificial light to reduce eye strain.

Reduce glare and position screens at eye level for good posture.

Proper awareness about myopia should be provided and its related causes with management strategies.

Appointments with an ophthalmologist and preventing recurrence of disorder is an ongoing life-long effort.

Use of Anticholinergic agent

Atropine:

It relaxes the eye’s accommodative muscles and suppresses axial elongation.

use-of-intervention-with-a-procedure-in-treating-myopia

Procedures can intervene directly on the eye to manage myopia progression including:

Refractive Surgery

Phakic Intraocular Lenses

Corneal Ring Segments

use-of-phases-in-managing-myopia

In the initial diagnosis phase, the focus is to establish the severity of myopia, progression rate, and any associated risk factors.

Pharmacologic therapy is effective in the treatment phase as it includes the use of anticholinergic agents.

In supportive care and management phase, patients should receive required attention such as lifestyle modification and surgical interventional therapies.

The regular follow-up visits with the ophthalmologist are scheduled to check the improvement of patients along with treatment response.

Medication

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Myopia

Updated : December 25, 2024

Mail Whatsapp PDF Image



Myopia causes blurred distance vision while close vision remains clear. It allows clear vision of nearby objects but causes difficulty with distant ones.

Myopia is the medical term for near-sightedness. It includes simple myopia and pathologic myopia.

Simple myopia can be corrected with glasses or lenses, but pathologic myopia may not achieve clear vision even with correction.

Myopia can be inherited and developed through lifestyle choices. Individual can read maps but struggle with driving due to vision.

Close-up tasks like reading or using computers can lead to myopia development. When the eyeball is elongated or the cornea is overly curved, light entering the eye misfocusess.

Myopia types as follows:

Simple/school myopia

Degenerative/malignant myopia

Myopia affects many worldwide, especially in East Asia, where over 80% of young adults are impacted.

It develops in childhood and progresses through adolescence. The rate of progression slows in adulthood.

Myopia is increasingly prevalent globally and, in the U.S., yet limited domestic research exists due to inconsistent definitions.

An estimated 50% of the global population are projected to be myopic by 2050 with nearly 10% at risk of high myopia.

Lung axial length relative to optical power causes excessive refractive power in the cornea/lens to light focusing in front of the retina.

Excessive curvature of cornea or lens enhances eye refractive power.

A hypothesis posits that peripheral light focusing behind the retina signals the eye to elongate through retinal signalling pathways.

The retina detects signals, and dopamine prevents excessive elongation through biochemical pathways.

The choroid thins in myopic eyes while near-work activities and low outdoor light contribute to myopia progression.

The causes of myopia are:

Genetic Factors

Environmental Factors

Optical Factors

Lifestyle and Behavioral Factors

Earlier onset of myopia increases risk of rapid progression and severity in adulthood during growth years.

Children are more likely to develop myopia if one or both parents are myopic.

Higher initial refractive error leads to faster progression, while mild myopia in adults progresses less.

Prolonged near work without breaks accelerates myopia progression significantly.

Collect details including presenting symptoms, vision and medical history to understand clinical history of patient.

Visual Acuity Testing

Pupil Examination

External Eye Examination

Slit Lamp Examination

Blurred distance vision, difficulty reading or seeing details, asthenopia, and night vision problems.

Hyperopia

Astigmatism

Anisometropia

Amblyopia

Glasses have been used for centuries to correct/improve blurry distance vision. The concave lens is thinnest in the middle that allows parallel light rays.

Plastic lenses are favoured for their lightweight properties, and polycarbonate lenses protect children’s eyes.

The traditional lens design for myopia blur treatment is single-vision unlike bifocals with two or progressive-addition lenses with gradual power increase.

Rigid gas permeable lenses are hard plastic contact lenses that correct myopic blur and are worn directly on the cornea.

Ophthalmology

Natural light regulates eye growth and decreases near activity time.

Promote reading by windows and minimize artificial light to reduce eye strain.

Reduce glare and position screens at eye level for good posture.

Proper awareness about myopia should be provided and its related causes with management strategies.

Appointments with an ophthalmologist and preventing recurrence of disorder is an ongoing life-long effort.

Ophthalmology

Atropine:

It relaxes the eye’s accommodative muscles and suppresses axial elongation.

Ophthalmology

Procedures can intervene directly on the eye to manage myopia progression including:

Refractive Surgery

Phakic Intraocular Lenses

Corneal Ring Segments

Ophthalmology

In the initial diagnosis phase, the focus is to establish the severity of myopia, progression rate, and any associated risk factors.

Pharmacologic therapy is effective in the treatment phase as it includes the use of anticholinergic agents.

In supportive care and management phase, patients should receive required attention such as lifestyle modification and surgical interventional therapies.

The regular follow-up visits with the ophthalmologist are scheduled to check the improvement of patients along with treatment response.

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