As part of infection prevention, nasal decolonization reduces nasal bacteria (e.g., S aureus) to decrease pathogen transmission risk.
Use a swab to clean the nose up to four times a day
Dose Adjustments
Use by medical professionals
Hospital workers who tested positive for carrying S. aureus in their noses were treated with three treatments at 4-hour intervals during the workday.
Antiseptics resulted in a statistically significant decrease in colony-forming units compared to placebo, by a median of 99% and a mean of 82%.
When compared with the placebo, the total number of bacterial colony-forming units saw a reduction of 71% (mean) and 91% (median), respectively (P<0.001).
Use with different populations.
In patients and carers who are carriers, a portion of postoperative/discharge care
Instead of isolation, use in S. aureus nasal carriers
Extended release: 120 mg orally every 2 times a day or 240 mg orally every once a day
Immediate release: 60 mg orally every 4 to 6 times a day when necessary
Extended release: 120 mg orally every 2 times a day or 240 mg orally every once a day
Immediate release: 60 mg orally every 4 to 6 times a day when necessary
Take 1 capsule orally every 4 to 6 hours and a daily dose not more than 4 capsules
Take 20 ml liquid orally every 6 hours and a daily dose not more than 80 mg
Recommended maximum dosage limits
For brompheniramine: take 24 mg orally in a day
For pseudoephedrine: take 240 mg orally in a day Administration
Administer liquids with measuring device for exact dose
Indicated for Nasal Congestion
One tablet of 25 mg of chlorcyclizine/60 mg of pseudoephedrine orally three-four times a day
It should not exceed 3 tablets in a day
Or
10 ml of 9.375 mg of chlorcyclizine/30 mg of pseudoephedrine orally four times a day
It should not exceed 40 ml in a day
1 spray into either of the nostrils up to 3times per day with minimum gap of 6 hours
Note: total administration per day should not exceed three sprays into either of the nostril
Duration of treatment should not be more than 7 days
(1.2 mg/2 mg)/1 mL] orally every 4-6 hours as 3 ml of solution Do not exceed the dose of more than 18 mL/24 hour [(4 mg/10 mg)/5 mL] orally every 4-6 hours as a 5 ml solution Do not exceed the dose of more than 30 mL/24 hour
[(1mg/2.5mg)/5mL] orally every 4-6 hours as 20 ml solution Do not exceed more than 120 mL/24 hour
Indicated for Nasal congestion and cough Bromfed DM- 10 ml or 2 teaspoonfuls orally every 4 hours Do not exceed more than 6 doses/day Bromaline DM- 20 ml or 4 teaspoonfuls orally every 4-6 hours Do not exceed more than 4 doses/day Bromdex D- 5ml or 1 teaspoonful orally every 4 hours; Do not exceed more than 4 doses/day
As part of infection prevention, nasal decolonization reduces nasal bacteria (e.g., S aureus) to decrease pathogen transmission risk
Use a swab to clean the nose up to four times a day
Dose Adjustments
Use by medical professionals
Hospital workers who tested positive for carrying S. aureus in their noses were treated with three treatments at 4-hour intervals during the workday.
Antiseptics resulted in a statistically significant decrease in colony-forming units compared to placebo, by a median of 99% and a mean of 82%.
When compared with the placebo, the total number of bacterial colony-forming units saw a reduction of 71% (mean) and 91% (median), respectively (P<0.001).
Use with different populations.
In patients and carers who are carriers, a portion of postoperative/discharge care
Instead of isolation, use in S. aureus nasal carriers
Below 2 yrs: Safety & efficacy were not established
2 to 6 yrs: 5 to 30 mg orally every 4-6 times a day when necessary
6 to 12 yrs: 30 mg orally every 4-6 times a day, OR 4 mg/kg daily divided every 4 times a day; should not exceed more than 120 mg daily
Above 12 yrs: 60 mg Orally every 4 times a day when necessary (immediate release); 120 mg orally every 2 times a day or 240 mg orally every once a day (extended release)
<12 years: Safety and efficacy not determined
>12 years: take 1 capsule orally every 4 to 6 hours and a daily dose not more than 4 capsules
6 to 12 years: take 10 ml liquid orally every 4 to 6 hours and a daily dose not more than 40 ml
>12 years: take 20 ml liquid orally every 4 to 6 hours and a daily dose not more than 80 ml
dexchlorpheniramine/pseudoephedrine
(3 mg/50 mg)/5 mL
oral suspension
For children aged 2 to 5 years, The recommended dosage is orally 2.5 to 5 mL every 12 hours, with a maximum daily intake of 10 mL
For children aged 6 to 11 years, The recommended dosage is orally 5 to 7.5 mL every 12 hours, with a maximum daily intake of 15 mL
For children aged 12 years or older, The recommended dosage is orally 15 mL every 12 hours, with a maximum daily intake of 30 mL
Indicated for Nasal Congestion
Age 6-11 years
Half-tablet of 25 mg of chlorcyclizine/60 mg of pseudoephedrine orally three-four times a day
It should not exceed one and Half tablets in a day
Or
5 ml of 9.375 mg of chlorcyclizine/30 mg of pseudoephedrine orally four times a day
It should not exceed 20 ml in a day
Age >12 years
One tablet of 25 mg of chlorcyclizine/60 mg of pseudoephedrine orally three-four times a day
It should not exceed 3 tablets in a day
Or
10 ml of 9.375 mg of chlorcyclizine/30 mg of pseudoephedrine orally four times a day
It should not exceed 40 ml in a day
2-6 years: 6.25 mg is given orally 6 times daily. Maximum dose is 37.5 mg daily
6-12 years: 12.5 mg is given orally 6 times daily. Maximum dose is 75 mg daily
above 12 years: 25 mg is given orally 6 times daily or 75 mg is given orally as extended-release tablet every 2 times a day. Should not exceed more than 150 mg daily
For more than 12 years- [(1.2 mg/2 mg)/1 mL] orally every 4-6 hours as 3 ml of solution Do not exceed the dose of more than 18 mL/24 hour For 6-12 years- [(1mg/2.5mg)/5mL] orally every 4-6 hours as 10 ml solution
Do not exceed more than 120 mL/24 hour
Bromfed DM- 10 ml or 2 teaspoonfuls orally every 4 hours Do not exceed more than 6 doses/day Bromaline DM- 20 ml or 4 teaspoonfuls orally every 4-6 hours Do not exceed more than 4 doses/day Bromdex D- 5ml or 1 teaspoonful orally every 4 hours; Do not exceed more than 4 doses/day
Bromaline DM For <6 years- As directed by the physician 6-12 years: 10 ml or 2 teaspoonfuls orally every 4 hours Do not exceed more than 4 doses/day For >12 years- 20 ml or 4 teaspoonfuls orally every 4-6 hours Do not exceed more than 4 doses/day For 6 months-2 years: As directed by the physician For 2-6 years- 2.5 ml or half teaspoonful orally every 4 hours Do not exceed more than 6 doses/day For 6-12 years- 5 ml or 1 teaspoonful orally every 4 hours Do not exceed more than 6 doses/day For >12 years- 10 ml or 2 teaspoonfuls orally every 4 hours Do not exceed more than 6 doses/day
Bromdex D For <6 years- As directed by the physician For 6-12 years- 2.5 mL orally every 6 hours as required Do not exceed more than 4 doses each day For >12 years- 5 mL orally every 6 hours as required; Do not exceed more than 4 doses each day
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