Pleurodynia is an infectious viral disease which is also called epidemic myalgia or Bornholm disease. It is characterized by the short-term severe chest stabbing pain and high temperature. The definition of “pleurodynia” came from the Greek words “pleura” meaning “rib or side” and “odynia” or “pain”.
The main etiological agent of pleurodynia is Coxsackievirus B which belongs to Coxsackievirus genus of Enterovirus. The most prominent feature of pleurodynia is chest pain which tends to be worsened by motion or breathing. The pain may be referred to the lumbar or abdomen. The viral infection is transmitted through the air which is caused by coughing and sneezing. The virus can be transmitted via direct personal contact by touching contaminated surfaces and the other routes.
Epidemiology
The occurrence characteristic of pleurodynia is sporadic. There are events that could be identified in different places around the globe. The main season for the incidence of pleurodynia is September through October. Advance enteroviruses such as Coxsackievirus B have also been related to increased cases during this hot season period. Unlike other illnesses– pleurodynia occur comparatively more in young adults and children than in any other age group. Older adults may be also immersed– but severe cases and complications are less likely to hit this cluster of age. Enteroviruses– including the Coxsackievirus B– are primarily transmitted through oral-fecal route and respiratory secretions.
Anatomy
Pathophysiology
Coxsackievirus B enters the body’s system through the airways or intestinal tract that can occur via droplets or fecal-oral transmission. The main route it follows is via mucous membrane cells in the respiratory or digestive systems. And the circulation of blood stream allows it to cause systemic involvement. The virus is a significant attribution factor to muscle tissue that can be felt as pleuritis. The virus gets into muscle cells and damages them– making them become inflamed. The infection generates an immune reaction and hence the fever– tiredness and muscle pains become the results. Sarcopenia– the pathological inflammation of muscles– is the primary indication of pleurodynia. The chest pain is said to be triggered by the muscle intercostal muscle involvement.
Etiology
Enterovirus B– popularly referred to as Coxsackievirus B is the principal potential contributor to stabilia– which is the medical condition. On top of it– hepatitis– enteritis– and respiratory affections are among the caused diseases. In addition to Echoviruses– other strains and types of enteroviruses have been linked. People’s resistance to the developing condition varies across the population; those who have never encountered the serotype before are more at risk. Some protection might come from wild-type infection immunity (especially serious cases). Published literature frequently emphasizes that pleurodynia and enterovirus infections have typical seasonal distribution with the peak incidence in the heating season–approximately end of summer and early autumn.
Genetics
Prognostic Factors
While pleurodynia can be experienced by men and women of any age– it is typically seen in children and adolescents. In this age groups however– the illness is usually mild and the prognosis is excellent. The nature of my symptoms– especially the chest pain intensity and the portion of the body involved– may have an impact on how I experience this disease. Mild cases that involve minimal or less severe symptoms usually have a good recovery. Appearance of a complication in connection with pleurodynia is not common– but is possible. Cases of myocarditis or pericarditis for instance– can occur in certain instances. The occurrence of difficulties complicates a patient’s prognosis– and they may need further medical support.
Clinical History
Pleurodynia is not common in children– while the condition is often less severe in this age range.
Physical Examination
Chest pain and assessment
Musculoskeletal Exam
Vital Signs
Age group
Associated comorbidity
Immunocompromised Individuals: Cases with pleurisy– especially those in people with poor immunity levels– may become very painful. Pregnant Women: Symptoms are comparable with the general adult population– but the close monitoring of disease progression is essential since pregnancy exposes women to the threat of viral infections. Active Individuals: Instances such as an exhaustive workout can trigger obvious symptoms that might have a negative effect on the athlete’s performance. Acuity of Presentation: The classic scenario of pleurodynia involves features that include acute onset of symptoms– in some cases associated with fever– muscle malaise– and joint pains. Severity of Chest Pain: The severity symptoms varies from mild to severe– however– coughing is typically aggravated by movement– deeps breathing– and examination.
Associated activity
Acuity of presentation
Sudden Onset:
Pleurodynia typically presents with a sudden onset of symptoms.
The abrupt development of severe chest pain is a key feature, often leading individuals to seek medical attention.
Fever and Malaise:
Fever, along with general malaise and muscle aches, may accompany chest pain.
The overall acuity of the presentation can vary, with some individuals experiencing more systemic symptoms than others.
Severity of Chest Pain:
The severity of chest pain varies, and it may range from mild to severe.
Pain is often worsened by movement, deep breathing, or palpation of the affected area.
Differential Diagnoses
Pneumonia
Pleuritis
Pulmonary Embolism
Myocardial Infarction
Costochondritis
Gastroesophageal Reflux Disease
Musculoskeletal Strain
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
Pain Management: Use NSAIDs and analgesics to manage fever and chest pain.
Rest: Restrict activities that worsen chest pain or strain muscles.
Hydration: Maintain proper hydration- especially during fever.
Warm Compresses: Use pads or compresses to relax muscles and reduce discomfort.
Role of Experimental Antiviral Treatments for Pleurodynia
Arbidol: Apuderit (apoderas) a Arbidol la cantidad de daño de las célulasprovocadosporel coxsackievirus-5 (CVB5). On the one hand– when used both on lab-grown cells and inside living organisms– it leads to a decrease in the levels of CVB5-RNA– the viral genetic material. By using BALB/c mice as an experimental model for systemic infection with CVB5– this study tested the hypothesis. This reveals that the data provided were obtained when the animals were wholly infected with the CVB5 CVB5. Interleukin-12 (IL-12): Through genetically modified one sub-type of Bifidobacterium longum which will be used to deliver this response protein. It reduces the amount of virus (viral titers) and the spleen severity of the virus damage which causes myocarditis– or swelling of the heart muscle. Mice of the BALB/c strain was utilized to produce CVB3 in vitro myocarditis through ex vivo inoculation.
Intercostal Nerve Block: For pain relief inchest wall (intercostal) insertion of the local anesthetic (e.g. lidocaine) near the afflicted nerve- which is located between the ribs. Through the interruption of the impulse transmission from afflicted area- the nerve blockade does block the unpleasant symptoms of the inflammation of the lining around the lungs.
Epidural Analgesia: The given choice may even be taken into account during the times when required. Specifically- the doctor gives the patient sedatives or local anesthetics to desensitize particular areas close to the spine. In his extreme cases- the patient may be assisted by using epidural anesthesia to alleviate or even erase the pain he is feeling in the chest and ribcage.
use-of-phases-in-managing-pleurodynia
Confirm diagnosis through clinical assessment- medical history review- and diagnostic tests.
Provide patient education on pleurodynia- its course- and expected symptoms.
Alleviate pain and discomfort with analgesic medications and rest.
Consider interventional procedures for severe symptoms.
Support recovery and return to normal activities.
Monitor for signs of recurrence or complications.
Educate on recurrence prevention and managing triggers.
Pleurodynia is an infectious viral disease which is also called epidemic myalgia or Bornholm disease. It is characterized by the short-term severe chest stabbing pain and high temperature. The definition of “pleurodynia” came from the Greek words “pleura” meaning “rib or side” and “odynia” or “pain”.
The main etiological agent of pleurodynia is Coxsackievirus B which belongs to Coxsackievirus genus of Enterovirus. The most prominent feature of pleurodynia is chest pain which tends to be worsened by motion or breathing. The pain may be referred to the lumbar or abdomen. The viral infection is transmitted through the air which is caused by coughing and sneezing. The virus can be transmitted via direct personal contact by touching contaminated surfaces and the other routes.
The occurrence characteristic of pleurodynia is sporadic. There are events that could be identified in different places around the globe. The main season for the incidence of pleurodynia is September through October. Advance enteroviruses such as Coxsackievirus B have also been related to increased cases during this hot season period. Unlike other illnesses– pleurodynia occur comparatively more in young adults and children than in any other age group. Older adults may be also immersed– but severe cases and complications are less likely to hit this cluster of age. Enteroviruses– including the Coxsackievirus B– are primarily transmitted through oral-fecal route and respiratory secretions.
Coxsackievirus B enters the body’s system through the airways or intestinal tract that can occur via droplets or fecal-oral transmission. The main route it follows is via mucous membrane cells in the respiratory or digestive systems. And the circulation of blood stream allows it to cause systemic involvement. The virus is a significant attribution factor to muscle tissue that can be felt as pleuritis. The virus gets into muscle cells and damages them– making them become inflamed. The infection generates an immune reaction and hence the fever– tiredness and muscle pains become the results. Sarcopenia– the pathological inflammation of muscles– is the primary indication of pleurodynia. The chest pain is said to be triggered by the muscle intercostal muscle involvement.
Enterovirus B– popularly referred to as Coxsackievirus B is the principal potential contributor to stabilia– which is the medical condition. On top of it– hepatitis– enteritis– and respiratory affections are among the caused diseases. In addition to Echoviruses– other strains and types of enteroviruses have been linked. People’s resistance to the developing condition varies across the population; those who have never encountered the serotype before are more at risk. Some protection might come from wild-type infection immunity (especially serious cases). Published literature frequently emphasizes that pleurodynia and enterovirus infections have typical seasonal distribution with the peak incidence in the heating season–approximately end of summer and early autumn.
While pleurodynia can be experienced by men and women of any age– it is typically seen in children and adolescents. In this age groups however– the illness is usually mild and the prognosis is excellent. The nature of my symptoms– especially the chest pain intensity and the portion of the body involved– may have an impact on how I experience this disease. Mild cases that involve minimal or less severe symptoms usually have a good recovery. Appearance of a complication in connection with pleurodynia is not common– but is possible. Cases of myocarditis or pericarditis for instance– can occur in certain instances. The occurrence of difficulties complicates a patient’s prognosis– and they may need further medical support.
Pleurodynia is not common in children– while the condition is often less severe in this age range.
Chest pain and assessment
Musculoskeletal Exam
Vital Signs
Immunocompromised Individuals: Cases with pleurisy– especially those in people with poor immunity levels– may become very painful. Pregnant Women: Symptoms are comparable with the general adult population– but the close monitoring of disease progression is essential since pregnancy exposes women to the threat of viral infections. Active Individuals: Instances such as an exhaustive workout can trigger obvious symptoms that might have a negative effect on the athlete’s performance. Acuity of Presentation: The classic scenario of pleurodynia involves features that include acute onset of symptoms– in some cases associated with fever– muscle malaise– and joint pains. Severity of Chest Pain: The severity symptoms varies from mild to severe– however– coughing is typically aggravated by movement– deeps breathing– and examination.
Sudden Onset:
Pleurodynia typically presents with a sudden onset of symptoms.
The abrupt development of severe chest pain is a key feature, often leading individuals to seek medical attention.
Fever and Malaise:
Fever, along with general malaise and muscle aches, may accompany chest pain.
The overall acuity of the presentation can vary, with some individuals experiencing more systemic symptoms than others.
Severity of Chest Pain:
The severity of chest pain varies, and it may range from mild to severe.
Pain is often worsened by movement, deep breathing, or palpation of the affected area.
Pneumonia
Pleuritis
Pulmonary Embolism
Myocardial Infarction
Costochondritis
Gastroesophageal Reflux Disease
Musculoskeletal Strain
Pain Management: Use NSAIDs and analgesics to manage fever and chest pain.
Rest: Restrict activities that worsen chest pain or strain muscles.
Hydration: Maintain proper hydration- especially during fever.
Warm Compresses: Use pads or compresses to relax muscles and reduce discomfort.
Rest and Activity Modification
Breathing Exercises
Heat Therapy
Cold Therapy
Positional Changes
Arbidol: Apuderit (apoderas) a Arbidol la cantidad de daño de las célulasprovocadosporel coxsackievirus-5 (CVB5). On the one hand– when used both on lab-grown cells and inside living organisms– it leads to a decrease in the levels of CVB5-RNA– the viral genetic material. By using BALB/c mice as an experimental model for systemic infection with CVB5– this study tested the hypothesis. This reveals that the data provided were obtained when the animals were wholly infected with the CVB5 CVB5. Interleukin-12 (IL-12): Through genetically modified one sub-type of Bifidobacterium longum which will be used to deliver this response protein. It reduces the amount of virus (viral titers) and the spleen severity of the virus damage which causes myocarditis– or swelling of the heart muscle. Mice of the BALB/c strain was utilized to produce CVB3 in vitro myocarditis through ex vivo inoculation.
Intercostal Nerve Block: For pain relief inchest wall (intercostal) insertion of the local anesthetic (e.g. lidocaine) near the afflicted nerve- which is located between the ribs. Through the interruption of the impulse transmission from afflicted area- the nerve blockade does block the unpleasant symptoms of the inflammation of the lining around the lungs.
Epidural Analgesia: The given choice may even be taken into account during the times when required. Specifically- the doctor gives the patient sedatives or local anesthetics to desensitize particular areas close to the spine. In his extreme cases- the patient may be assisted by using epidural anesthesia to alleviate or even erase the pain he is feeling in the chest and ribcage.
Confirm diagnosis through clinical assessment- medical history review- and diagnostic tests.
Provide patient education on pleurodynia- its course- and expected symptoms.
Alleviate pain and discomfort with analgesic medications and rest.
Consider interventional procedures for severe symptoms.
Support recovery and return to normal activities.
Monitor for signs of recurrence or complications.
Educate on recurrence prevention and managing triggers.
Pleurodynia is an infectious viral disease which is also called epidemic myalgia or Bornholm disease. It is characterized by the short-term severe chest stabbing pain and high temperature. The definition of “pleurodynia” came from the Greek words “pleura” meaning “rib or side” and “odynia” or “pain”.
The main etiological agent of pleurodynia is Coxsackievirus B which belongs to Coxsackievirus genus of Enterovirus. The most prominent feature of pleurodynia is chest pain which tends to be worsened by motion or breathing. The pain may be referred to the lumbar or abdomen. The viral infection is transmitted through the air which is caused by coughing and sneezing. The virus can be transmitted via direct personal contact by touching contaminated surfaces and the other routes.
The occurrence characteristic of pleurodynia is sporadic. There are events that could be identified in different places around the globe. The main season for the incidence of pleurodynia is September through October. Advance enteroviruses such as Coxsackievirus B have also been related to increased cases during this hot season period. Unlike other illnesses– pleurodynia occur comparatively more in young adults and children than in any other age group. Older adults may be also immersed– but severe cases and complications are less likely to hit this cluster of age. Enteroviruses– including the Coxsackievirus B– are primarily transmitted through oral-fecal route and respiratory secretions.
Coxsackievirus B enters the body’s system through the airways or intestinal tract that can occur via droplets or fecal-oral transmission. The main route it follows is via mucous membrane cells in the respiratory or digestive systems. And the circulation of blood stream allows it to cause systemic involvement. The virus is a significant attribution factor to muscle tissue that can be felt as pleuritis. The virus gets into muscle cells and damages them– making them become inflamed. The infection generates an immune reaction and hence the fever– tiredness and muscle pains become the results. Sarcopenia– the pathological inflammation of muscles– is the primary indication of pleurodynia. The chest pain is said to be triggered by the muscle intercostal muscle involvement.
Enterovirus B– popularly referred to as Coxsackievirus B is the principal potential contributor to stabilia– which is the medical condition. On top of it– hepatitis– enteritis– and respiratory affections are among the caused diseases. In addition to Echoviruses– other strains and types of enteroviruses have been linked. People’s resistance to the developing condition varies across the population; those who have never encountered the serotype before are more at risk. Some protection might come from wild-type infection immunity (especially serious cases). Published literature frequently emphasizes that pleurodynia and enterovirus infections have typical seasonal distribution with the peak incidence in the heating season–approximately end of summer and early autumn.
While pleurodynia can be experienced by men and women of any age– it is typically seen in children and adolescents. In this age groups however– the illness is usually mild and the prognosis is excellent. The nature of my symptoms– especially the chest pain intensity and the portion of the body involved– may have an impact on how I experience this disease. Mild cases that involve minimal or less severe symptoms usually have a good recovery. Appearance of a complication in connection with pleurodynia is not common– but is possible. Cases of myocarditis or pericarditis for instance– can occur in certain instances. The occurrence of difficulties complicates a patient’s prognosis– and they may need further medical support.
Pleurodynia is not common in children– while the condition is often less severe in this age range.
Chest pain and assessment
Musculoskeletal Exam
Vital Signs
Immunocompromised Individuals: Cases with pleurisy– especially those in people with poor immunity levels– may become very painful. Pregnant Women: Symptoms are comparable with the general adult population– but the close monitoring of disease progression is essential since pregnancy exposes women to the threat of viral infections. Active Individuals: Instances such as an exhaustive workout can trigger obvious symptoms that might have a negative effect on the athlete’s performance. Acuity of Presentation: The classic scenario of pleurodynia involves features that include acute onset of symptoms– in some cases associated with fever– muscle malaise– and joint pains. Severity of Chest Pain: The severity symptoms varies from mild to severe– however– coughing is typically aggravated by movement– deeps breathing– and examination.
Sudden Onset:
Pleurodynia typically presents with a sudden onset of symptoms.
The abrupt development of severe chest pain is a key feature, often leading individuals to seek medical attention.
Fever and Malaise:
Fever, along with general malaise and muscle aches, may accompany chest pain.
The overall acuity of the presentation can vary, with some individuals experiencing more systemic symptoms than others.
Severity of Chest Pain:
The severity of chest pain varies, and it may range from mild to severe.
Pain is often worsened by movement, deep breathing, or palpation of the affected area.
Pneumonia
Pleuritis
Pulmonary Embolism
Myocardial Infarction
Costochondritis
Gastroesophageal Reflux Disease
Musculoskeletal Strain
Pain Management: Use NSAIDs and analgesics to manage fever and chest pain.
Rest: Restrict activities that worsen chest pain or strain muscles.
Hydration: Maintain proper hydration- especially during fever.
Warm Compresses: Use pads or compresses to relax muscles and reduce discomfort.
Rest and Activity Modification
Breathing Exercises
Heat Therapy
Cold Therapy
Positional Changes
Arbidol: Apuderit (apoderas) a Arbidol la cantidad de daño de las célulasprovocadosporel coxsackievirus-5 (CVB5). On the one hand– when used both on lab-grown cells and inside living organisms– it leads to a decrease in the levels of CVB5-RNA– the viral genetic material. By using BALB/c mice as an experimental model for systemic infection with CVB5– this study tested the hypothesis. This reveals that the data provided were obtained when the animals were wholly infected with the CVB5 CVB5. Interleukin-12 (IL-12): Through genetically modified one sub-type of Bifidobacterium longum which will be used to deliver this response protein. It reduces the amount of virus (viral titers) and the spleen severity of the virus damage which causes myocarditis– or swelling of the heart muscle. Mice of the BALB/c strain was utilized to produce CVB3 in vitro myocarditis through ex vivo inoculation.
Intercostal Nerve Block: For pain relief inchest wall (intercostal) insertion of the local anesthetic (e.g. lidocaine) near the afflicted nerve- which is located between the ribs. Through the interruption of the impulse transmission from afflicted area- the nerve blockade does block the unpleasant symptoms of the inflammation of the lining around the lungs.
Epidural Analgesia: The given choice may even be taken into account during the times when required. Specifically- the doctor gives the patient sedatives or local anesthetics to desensitize particular areas close to the spine. In his extreme cases- the patient may be assisted by using epidural anesthesia to alleviate or even erase the pain he is feeling in the chest and ribcage.
Confirm diagnosis through clinical assessment- medical history review- and diagnostic tests.
Provide patient education on pleurodynia- its course- and expected symptoms.
Alleviate pain and discomfort with analgesic medications and rest.
Consider interventional procedures for severe symptoms.
Support recovery and return to normal activities.
Monitor for signs of recurrence or complications.
Educate on recurrence prevention and managing triggers.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Digital Certificate PDF
On course completion, you will receive a full-sized presentation quality digital certificate.
medtigo Simulation
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
medtigo Points
medtigo points is our unique point redemption system created to award users for interacting on our site. These points can be redeemed for special discounts on the medtigo marketplace as well as towards the membership cost itself.
Community Forum post/reply = 5 points
*Redemption of points can occur only through the medtigo marketplace, courses, or simulation system. Money will not be credited to your bank account. 10 points = $1.
All Your Certificates in One Place
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
