Replacement Solution

Updated: July 3, 2024

Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

sodium chloride/sodium citrate

The prefilter infusion rate is adjusted based on the blood flow rate in order to reach a desired blood citrate level of 3 to 4 mmol/L
The flow rate for anticoagulation of the extracorporeal circuit should be adjusted to achieve a post-filter ionized calcium level of 0.25 to 0.35 mmol/L
Dosing modification
Renal Impairment
Dose modification not required
Hepatic Impairment
Mild to moderate:
Observe for citrate accumulation
Severe impairment:
Stop using in patients with severe failure