Smoking Cessation

Updated: July 16, 2024

Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

nicotine intranasal

1 - 2

sprays

each nostril every hour up to 10-12 sprays per day for about 3 months, `
The maximum dose per day is 40 mg
one dose of spray contains 0.5 mg of nicotine.

bupropion

150

Tablet

Orally 

once a day

days

nortriptyline

25mg orally every day

nicotine intranasal

One spray each nostril (i.e., two sprays to deliver one dose of 1 mg); usually, 10–12 sprays per day in each nostril when required
Start with 1-2 doses/hour; for best results, advise the patient to use at least 8 doses per day at start.
Depending on addiction, the amount may be increased up to a maximum of 40 mg (80 sprays per day).

Dose Adjustments

Administration
Gently tilt head while administering
Avoid sniffing, swallowing, and inhaling through the nose while the spray is being administered.

bupropion

150 mg orally each day for 3 days
Increase the dose to 150 mg every 12 hours
Continue the treatment for up to 7-12 weeks
If successful quit occurs after 7-12 weeks, consider a maintenance therapy

nicotine transdermal

More than 10 cigarettes daily
21/14/7-mg treatment regimen: 21-mg patch 1 time a day for about 6 weeks, following 14-mg patch 1 time a day for about 2 weeks, following 7-mg patch 1 time a day for about 2 weeks
Less than 10 cigarettes daily
14/7-mg treatment regimen: 14-mg patch 1 time a day for about 6 weeks, following 7-mg patch 1 time a day for about 2 weeks

clonidine

(Off-Label)
In smoking-addicted individuals, clonidine is given orally or via transdermal administration
If required, oral administration of 0.1 mg daily followed by a 0.1 mg/ day increase in dose up to 0.15 to 0.75 mg/day
Transdermal patch administration with 100 to 200 mcg/day every week:

Dose Adjustments

Not Available

Future Trends