Substance-Induced Mood Disorder

Updated: May 15, 2024

Mail Whatsapp PDF Image

Background

Substances of Intoxication and pharmacological drugs may cause paradoxical or affective disorder, therefore maniac or depressive states may appear as the result. These diseases called “substance induced” appear in the presence of substance usage. As part of the specifiers for mood disorders in DMS-IV, these diseases are now differentiated from the previously included substance-related mood disorders. Depressive and bipolar disorders tend to appear with substance use disorders (SUDs) and these forms of mental illness tend to affect the most people in the society. There are two categories of substance-induced mood disorders, including substance-induced bipolar disorders and depression that are part of substance-induced mood disorders.

Epidemiology

In accordance with the studies, 40 to 60% of the people with an alcohol addiction also have a dual diagnosis of depression resulted from the use of substances. The cumulative incidence is about 0.26% to 0.93% according to some studies. About 16.5% patients who have a major depression stat that they have alcohol use disorder and almost 18% are positive for substance use disorder, whereas in the outpatient care of substance abuse disorder, there are 55% indicated that they are depressed by substance. Depending on the patient, Bipolar I might have observed in 61% the total life incidence of drug abuse problems.

Anatomy

Pathophysiology

The substance-induced illnesses are not fully known for how they are developed yet. The list of the moved regions due to the drug-induced mood disorders comprises olfactory tubercle, frontal cortex, nucleus accumbens and hypothalamic. The depression relates to the drugs is a neurotransmitter modulator, corticotropin-releasing factors and human serotonin.

Etiology

Heavy alcohol use is the most prevalent cause of depressive episodes. Substance-induced disorders can arise from intoxication or withdrawal. By modifying neurotransmitter transmission in important brain circuits such as the Papez circuit and mesolimbic tract as these drugs can cause mania or sadness.

Genetics

Prognostic Factors

Conceptually, there should come that moment of time after abstinence, tears shed and nerves exhausted where all those depressed mood problems are gone. The best indicator of incidences that will occur in the future is to always emphasize abstinence. Those factors that inspire an abstinent life are always one of the more valuable things to be found in prison. As a matter of fact that the survival kit that we use for our recovery is taking drugs as prescribed, psychotherapy and stable families. On the other hand, they have a higher tendency to attract such places where substance abuse usually occurs and provide poor academic performance among the students.

Clinical History

A variety of age groups, including middle-aged individuals, the elderly, and teenagers and young adults, are commonly affected by substance use problems. Changes in social behavior, impulsivity, impatience, and mood swings are common among adolescents and young adults. In addition to stresses from job or family, middle-aged persons may have a more complex combination of mood symptoms and a longer history of drug use, which might result in more severe mood disorders. Medical comorbidities and age-related physiological changes might cause older people to have more complicated symptoms.

Substance use can increase symptoms of comorbid mental diseases, such as bipolar disorder or anxiety disorders, which can complicate treatment planning and clinical presentation. The way that mood symptoms manifest can also be influenced by substance use behaviors.

Physical Examination

The way one behaves, and the appearance is a key information provider on the state regarding physical health and any drug intake. Indicators of the use or absence of substance may be some symptoms such as aggressiveness or tiredness as well as poor appearance. Mechanical markers like temperature, blood pressure, heartbeat, or respiration rate literally count for things like increased autonomic hyperactivity or aggravating physiological distress. Centered on the nervous system, the study may demonstrate changes in the nerves or familiar neurological reactions like ataxia, tremors, or cognitive problems attributed to the drugs.

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Distinguishing transient substance-induced disorders from primary psychiatric conditions often involves observing the individual during a period of abstinence while considering the timing of substance intake. Additionally, a family history of primary psychiatric illness can aid in making this distinction. However, distinguishing substance-induced symptoms of mania may pose greater complexity due to the frequent temporal association or causal relationship between substance use and mood symptoms.

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

Handling Drug-Induced Mood Disorders: The initial sphere of attention will be dealing with the physiological symptoms of substance abuse. In most cases, people who have drug dependence or alcoholism need medical help to care for the conditions.

Psychoeducation: Knowing that the use of drugs can be related as either a cause or a symptom of depression, while some drugs may imitate mood disorders, and also knowing that quitting drugs makes mood more stable.

Psychiatric Evaluation and Diagnosis: A comprehensive research is needed to determine if the mood disorder is caused by the substances, or it is a different mental illness. Treatment plan options and customized approaches are also made based on the results.

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

use-of-a-non-pharmacological-approach-for-treating-substance-induced-mood-disorder

  • Patient Education: Education is notably important in demystifying the direct association between substance use and depressive moods, so individuals can make the right choices and rehabilitation will be more successful.
  • Stress Reduction: Interventions based on mindfulness, such as mindfulness meditation and mindfulness-based stress reduction (MBSR), enable people to upgrade their mental facilities and sharpen their awareness of their thoughts, feelings, and physical sensations, enhancing the ability to accept everything unconditionally regardless of evaluation.
  • Exercise: Routine exercise and physical activities can function simultaneously in neutralizing the moods, lessening stress, and uplifting the state of the mind web content.

Role of Antidepressants in the treatment of Substance-Induced Mood Disorder

The main essential drugs for antidepressants prescription are often assigned to patients with mental effects related from drug consumption or its discontinuation. Antidepressants promote mood stabilization and alleviate mood fluctuations that is usually manifested with the Substance Induced Mood Disorder. The drugs that act on the neurotransmitter systems which are thought to be responsible for the regulation of mood, i.e. serotonin and norepinephrine, help in achieving the equilibrium state of the mood. Those who are prone to Mood Disorders due to Substance Abuse could encounter other psychiatric issues also such as Major Depression and Generalized Anxiety Disorder. Psychotropic medications could be used to treat these depression-like symptoms of substance use disorder and the underlying conditions contributing to a depressed mood.

Role of Antipsychotics in the treatment of Substance-Induced Mood Disorder

Substance-Induced Mood Disorder can be partially managed by antipsychotic drugs, in which instances the patients have severe mood fluctuations such as psychosis or agitation due to drug use. Disorders related to the use of stimulants (for example, cocaine or amphetamines) are psychoses of a different nature manifested in the form of visions and bizarre ideas, not thinking in order. Antipsychotic drugs are the mainstay of treatment of psychotic features and symptoms and help to stabilize patients, removing the expressions of psychosis from their minds.

The Substance use disorder with induce mood disorder can be expressed through extremely severe provocation of agitation or aggression, especially at the height of intoxication or withdrawal. The anti-psychotics that have such side effects can be of great help, as they can calm down agitation, reduce the risk of self-harm as well as harm to others. The use of antipsychotics may prevent relapses in people having substance-induced mood disorders by dealing with underlying mood features and psychotic thoughts that contribute to substance abuse. The acting of these drugs on mood regulation and cravings control can aid in maintenance of the treatment.

use-of-intervention-with-a-procedure-in-treating-substance-induced-mood-disorder

Medical Intervention:

  • Detoxification: The process of detoxification, which is removal of the substance from a person’s biological systems, may be procured with substance detoxification. The approach, which is usually done under medical surveillance, could be used to manage withdrawal symptoms i.e. nausea and anxiety.
  • Medication: In other situations, medications such as prescribed for managing the withdrawal syndrome and for the treatment of the co-occurring mood disorder may be used. Indeed, in this way, antidepressants are usually used to treat depression syndrome.

Psychological Intervention:

  • Cognitive-Behavioral Therapy (CBT): CBT is a proposed method to help to deconstruct maladaptive thinking and behaviors individuals exhibit who suffer from substance use disorders or major depression. They enable people to acquire the necessary coping skills and strategies which allow them to master the management of cravings and mood requirements.
  • Motivational Interviewing: A of this kind allows users to investigate their hesitation towards change and develop a sense of their own drive urging them to change their habits.
  • Supportive Therapy: Through offering understanding and judgment-free atmosphere, the individuals with their substance use and content of their mood can be treated in a more effective way.

Social Intervention:

  • Support Groups: Attending support groups like Alcoholics Anonymous or Narcotics Anonymous for instance allows one to experience a group peer support and is reminded by others who had the similar struggles that one is on the right path.
  • Family Therapy: Incorporating a loved one in the therapy process can assist in better communication, find resolutions when conflict arise, and set up a caring environment for healing to work.
  • Lifestyle Changes: Impeding healthy lifestyle stipends by involving regular exercises, adequate sleep, and good health can help improve the overall health and recovery.

Relapse Prevention:

  • Developing a relapse prevention plan: Pinpointing triggers, warning signals, and coping strategies are the ways that boost on knowing and avoiding relapse.
  • Ongoing Support: It is the duty of the follow-up visits as much as the visits from health care providers, therapists, and support groups that will enable long-term recovery.

use-of-phases-in-managing-substance-induced-mood-disorder

Critically important are an evaluation and diagnostics of mood disorders that includes collecting information on person’s substance use history, symptoms, and any existing co-occurring mental health problems. The first step in most cases is a medically supervised detoxification for controlling the expression of withdrawal symptoms. After the detoxification is done, the next step is working to stabilize the person’s mood along with finding solutions to any immediate mental health challenges such as depression or anxiety. This treatment would not only include medications and therapy but also give the patients the tools of the trade through which they would be able to help themselves. A personalized treatment plan is formulated taking into account the individualized situation of the patient including their aims and tasks and including therapy, medication, support groups, and lifestyle adjustment to help the person overcome both the substance use and the mood disorder. Therapy, for instance, cognitivie-behavioral therapy (CBT), or dialectic behaviour therapy (DBT), or motivational interviewing, might as well be the types of therapy that can help the individual to realize what their mood symptoms and substance use have to do with each other, develop the ability to cope, and stay away from relapsing. Relapse prevention strategies are crucial part in managing SIMD as it allows individuals to identify triggers and develop healthier coping mechanisms as well as build support network.

Medication

Media Gallary

Content loading

Latest Posts

Substance-Induced Mood Disorder

Updated : May 15, 2024

Mail Whatsapp PDF Image



Substances of Intoxication and pharmacological drugs may cause paradoxical or affective disorder, therefore maniac or depressive states may appear as the result. These diseases called “substance induced” appear in the presence of substance usage. As part of the specifiers for mood disorders in DMS-IV, these diseases are now differentiated from the previously included substance-related mood disorders. Depressive and bipolar disorders tend to appear with substance use disorders (SUDs) and these forms of mental illness tend to affect the most people in the society. There are two categories of substance-induced mood disorders, including substance-induced bipolar disorders and depression that are part of substance-induced mood disorders.

In accordance with the studies, 40 to 60% of the people with an alcohol addiction also have a dual diagnosis of depression resulted from the use of substances. The cumulative incidence is about 0.26% to 0.93% according to some studies. About 16.5% patients who have a major depression stat that they have alcohol use disorder and almost 18% are positive for substance use disorder, whereas in the outpatient care of substance abuse disorder, there are 55% indicated that they are depressed by substance. Depending on the patient, Bipolar I might have observed in 61% the total life incidence of drug abuse problems.

The substance-induced illnesses are not fully known for how they are developed yet. The list of the moved regions due to the drug-induced mood disorders comprises olfactory tubercle, frontal cortex, nucleus accumbens and hypothalamic. The depression relates to the drugs is a neurotransmitter modulator, corticotropin-releasing factors and human serotonin.

Heavy alcohol use is the most prevalent cause of depressive episodes. Substance-induced disorders can arise from intoxication or withdrawal. By modifying neurotransmitter transmission in important brain circuits such as the Papez circuit and mesolimbic tract as these drugs can cause mania or sadness.

Conceptually, there should come that moment of time after abstinence, tears shed and nerves exhausted where all those depressed mood problems are gone. The best indicator of incidences that will occur in the future is to always emphasize abstinence. Those factors that inspire an abstinent life are always one of the more valuable things to be found in prison. As a matter of fact that the survival kit that we use for our recovery is taking drugs as prescribed, psychotherapy and stable families. On the other hand, they have a higher tendency to attract such places where substance abuse usually occurs and provide poor academic performance among the students.

A variety of age groups, including middle-aged individuals, the elderly, and teenagers and young adults, are commonly affected by substance use problems. Changes in social behavior, impulsivity, impatience, and mood swings are common among adolescents and young adults. In addition to stresses from job or family, middle-aged persons may have a more complex combination of mood symptoms and a longer history of drug use, which might result in more severe mood disorders. Medical comorbidities and age-related physiological changes might cause older people to have more complicated symptoms.

Substance use can increase symptoms of comorbid mental diseases, such as bipolar disorder or anxiety disorders, which can complicate treatment planning and clinical presentation. The way that mood symptoms manifest can also be influenced by substance use behaviors.

The way one behaves, and the appearance is a key information provider on the state regarding physical health and any drug intake. Indicators of the use or absence of substance may be some symptoms such as aggressiveness or tiredness as well as poor appearance. Mechanical markers like temperature, blood pressure, heartbeat, or respiration rate literally count for things like increased autonomic hyperactivity or aggravating physiological distress. Centered on the nervous system, the study may demonstrate changes in the nerves or familiar neurological reactions like ataxia, tremors, or cognitive problems attributed to the drugs.

Distinguishing transient substance-induced disorders from primary psychiatric conditions often involves observing the individual during a period of abstinence while considering the timing of substance intake. Additionally, a family history of primary psychiatric illness can aid in making this distinction. However, distinguishing substance-induced symptoms of mania may pose greater complexity due to the frequent temporal association or causal relationship between substance use and mood symptoms.

Handling Drug-Induced Mood Disorders: The initial sphere of attention will be dealing with the physiological symptoms of substance abuse. In most cases, people who have drug dependence or alcoholism need medical help to care for the conditions.

Psychoeducation: Knowing that the use of drugs can be related as either a cause or a symptom of depression, while some drugs may imitate mood disorders, and also knowing that quitting drugs makes mood more stable.

Psychiatric Evaluation and Diagnosis: A comprehensive research is needed to determine if the mood disorder is caused by the substances, or it is a different mental illness. Treatment plan options and customized approaches are also made based on the results.

Psychiatry/Mental Health

  • Patient Education: Education is notably important in demystifying the direct association between substance use and depressive moods, so individuals can make the right choices and rehabilitation will be more successful.
  • Stress Reduction: Interventions based on mindfulness, such as mindfulness meditation and mindfulness-based stress reduction (MBSR), enable people to upgrade their mental facilities and sharpen their awareness of their thoughts, feelings, and physical sensations, enhancing the ability to accept everything unconditionally regardless of evaluation.
  • Exercise: Routine exercise and physical activities can function simultaneously in neutralizing the moods, lessening stress, and uplifting the state of the mind web content.

Psychiatry/Mental Health

The main essential drugs for antidepressants prescription are often assigned to patients with mental effects related from drug consumption or its discontinuation. Antidepressants promote mood stabilization and alleviate mood fluctuations that is usually manifested with the Substance Induced Mood Disorder. The drugs that act on the neurotransmitter systems which are thought to be responsible for the regulation of mood, i.e. serotonin and norepinephrine, help in achieving the equilibrium state of the mood. Those who are prone to Mood Disorders due to Substance Abuse could encounter other psychiatric issues also such as Major Depression and Generalized Anxiety Disorder. Psychotropic medications could be used to treat these depression-like symptoms of substance use disorder and the underlying conditions contributing to a depressed mood.

Psychiatry/Mental Health

Substance-Induced Mood Disorder can be partially managed by antipsychotic drugs, in which instances the patients have severe mood fluctuations such as psychosis or agitation due to drug use. Disorders related to the use of stimulants (for example, cocaine or amphetamines) are psychoses of a different nature manifested in the form of visions and bizarre ideas, not thinking in order. Antipsychotic drugs are the mainstay of treatment of psychotic features and symptoms and help to stabilize patients, removing the expressions of psychosis from their minds.

The Substance use disorder with induce mood disorder can be expressed through extremely severe provocation of agitation or aggression, especially at the height of intoxication or withdrawal. The anti-psychotics that have such side effects can be of great help, as they can calm down agitation, reduce the risk of self-harm as well as harm to others. The use of antipsychotics may prevent relapses in people having substance-induced mood disorders by dealing with underlying mood features and psychotic thoughts that contribute to substance abuse. The acting of these drugs on mood regulation and cravings control can aid in maintenance of the treatment.

Psychiatry/Mental Health

Medical Intervention:

  • Detoxification: The process of detoxification, which is removal of the substance from a person’s biological systems, may be procured with substance detoxification. The approach, which is usually done under medical surveillance, could be used to manage withdrawal symptoms i.e. nausea and anxiety.
  • Medication: In other situations, medications such as prescribed for managing the withdrawal syndrome and for the treatment of the co-occurring mood disorder may be used. Indeed, in this way, antidepressants are usually used to treat depression syndrome.

Psychological Intervention:

  • Cognitive-Behavioral Therapy (CBT): CBT is a proposed method to help to deconstruct maladaptive thinking and behaviors individuals exhibit who suffer from substance use disorders or major depression. They enable people to acquire the necessary coping skills and strategies which allow them to master the management of cravings and mood requirements.
  • Motivational Interviewing: A of this kind allows users to investigate their hesitation towards change and develop a sense of their own drive urging them to change their habits.
  • Supportive Therapy: Through offering understanding and judgment-free atmosphere, the individuals with their substance use and content of their mood can be treated in a more effective way.

Social Intervention:

  • Support Groups: Attending support groups like Alcoholics Anonymous or Narcotics Anonymous for instance allows one to experience a group peer support and is reminded by others who had the similar struggles that one is on the right path.
  • Family Therapy: Incorporating a loved one in the therapy process can assist in better communication, find resolutions when conflict arise, and set up a caring environment for healing to work.
  • Lifestyle Changes: Impeding healthy lifestyle stipends by involving regular exercises, adequate sleep, and good health can help improve the overall health and recovery.

Relapse Prevention:

  • Developing a relapse prevention plan: Pinpointing triggers, warning signals, and coping strategies are the ways that boost on knowing and avoiding relapse.
  • Ongoing Support: It is the duty of the follow-up visits as much as the visits from health care providers, therapists, and support groups that will enable long-term recovery.

Psychiatry/Mental Health

Critically important are an evaluation and diagnostics of mood disorders that includes collecting information on person’s substance use history, symptoms, and any existing co-occurring mental health problems. The first step in most cases is a medically supervised detoxification for controlling the expression of withdrawal symptoms. After the detoxification is done, the next step is working to stabilize the person’s mood along with finding solutions to any immediate mental health challenges such as depression or anxiety. This treatment would not only include medications and therapy but also give the patients the tools of the trade through which they would be able to help themselves. A personalized treatment plan is formulated taking into account the individualized situation of the patient including their aims and tasks and including therapy, medication, support groups, and lifestyle adjustment to help the person overcome both the substance use and the mood disorder. Therapy, for instance, cognitivie-behavioral therapy (CBT), or dialectic behaviour therapy (DBT), or motivational interviewing, might as well be the types of therapy that can help the individual to realize what their mood symptoms and substance use have to do with each other, develop the ability to cope, and stay away from relapsing. Relapse prevention strategies are crucial part in managing SIMD as it allows individuals to identify triggers and develop healthier coping mechanisms as well as build support network.

Free CME credits

Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.

Digital Certificate PDF

On course completion, you will receive a full-sized presentation quality digital certificate.

medtigo Simulation

A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.

medtigo Points

medtigo points is our unique point redemption system created to award users for interacting on our site. These points can be redeemed for special discounts on the medtigo marketplace as well as towards the membership cost itself.
 
  • Registration with medtigo = 10 points
  • 1 visit to medtigo’s website = 1 point
  • Interacting with medtigo posts (through comments/clinical cases etc.) = 5 points
  • Attempting a game = 1 point
  • Community Forum post/reply = 5 points

    *Redemption of points can occur only through the medtigo marketplace, courses, or simulation system. Money will not be credited to your bank account. 10 points = $1.

All Your Certificates in One Place

When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.

Our Certificate Courses