- September 2, 2022
- Newsletter
- 617-430-5616
Menu
» Home » CAD » Infectious Disease » Respiratory Tract Infection » Tonsillitis
ADVERTISEMENT
ADVERTISEMENT
» Home » CAD » Infectious Disease » Respiratory Tract Infection » Tonsillitis
Background
The lateral oropharynx contains the palatine or faucial tonsils. The palatine arches or pillars are situated between the palatoglossal arch anteriorly and the palatopharyngeal arch posteriorly. Along with the adenoids (nasopharyngeal tonsil), lingual tonsil, and tubal tonsil, the tonsils are made of lymphatic tissue and make up Waldeyer’s ring.
They act as the initial immunological barrier to insults, offering a crucial line of protection against inhaled or ingested microorganisms. Tonsillitis, or tonsil inflammation, is a typical condition that accounts for 1.3 percent of patient visits.
It usually manifests as a sore throat and is mostly caused by a bacterial or viral infection. A definitive diagnosis is an acute tonsillitis. It might be challenging to distinguish between viral and bacterial causes but doing so is essential to avoid the misuse of antibiotics.
Epidemiology
A sore throat is a reason for about 2 percent of ambulatory patient visits in the US. The sickness can happen at any time of the year; however, it is more common in the winter and spring seasons.
15 percent to 30 percent of patients under the age of five and 5 percent to 15 percent of individuals over the age of 15 have GABHS. Patients under five are more likely to experience viral causative agents. In children younger than two years old, GABHS is uncommon.
Anatomy
Pathophysiology
Etiology
Tonsillitis typically results from an infection, which could be bacterial or viral. The most frequent causes are viral causes. Common cold-causing viruses such as the respiratory syncytial virus, rhinovirus, coronavirus, and adenovirus are typically the most prevalent viral culprits. Typically, they are not particularly virulent and rarely cause problems.
Tonsillitis can also be brought on by other viruses like Epstein-Barr (which causes mononucleosis), rubella, HIV, hepatitis A, and cytomegalovirus (CMV). GABHS (Group A beta-hemolytic Streptococcus) is the most common cause of bacterial infections; however, Staphylococcus aureus, Haemophilus influenza, and Streptococcus pneumoniae have all been grown.
Pathogens that are both anaerobic and aerobic can cause bacterial tonsillitis. Even so, Corynebacterium diphtheriae, which causes diphtheria, should be considered as an etiology in unvaccinated individuals. HIV, chlamydia, syphilis, and gonorrhea are possible additional causes in people who engage in sexual activity. Clinicians should evaluate their patients’ risks because tuberculosis has also been linked to recurrent tonsillitis.
Genetics
Prognostic Factors
In the lack of complications, the outcome for acute tonsillitis is very good. The majority of instances are self-limiting illnesses in healthier patient groups, which cure quickly and leave few long-term effects. Even though patients with repeated infections may need surgery, their long-term outcome is still favorable.
Even individuals with problems such as Lemierre syndrome and peritonsillar abscess have great long-term results in the age of antibiotics. The long-term effects of GABHS problems, such as glomerulonephritis and rheumatic fever, can include heart valve disease and impaired kidney function.
In the developed world, these entities are extremely uncommon, and incidence has decreased since penicillin therapy became available. If symptoms don’t get better, a different diagnosis, such as chlamydia, HIV, gonorrhea, TB, syphilis, abscess, Kawasaki illness, Lemierre syndrome, and mononucleosis, should be considered. The underlying illness in these circumstances affects the overall outcome.
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
500
mg
2 times a day or 1 g daily
10
days
ER: 775 mg daily for 10 days
1.2 million units given IM daily as a single dose
400
mg
Orally
divided in to 2 times a day
10
days
Indicated for Streptococcal pharyngitis:
250 mg oral tablet immediate release twice a day for 14 days
250
mg
Capsule
Orally
every 6 hrs
1
g
orally
daily
10
days
Note: indicated for pharyngitis and tonsillitis caused by Group A beta-hemolytic streptococci
500 mg orally once a day, followed by 250 mg 4 times a day, on the 2nd to 5th day.
125 - 250
mg
Orally
every 8 hrs
10
days
Children and Adolescents: :
50 mg/kg/day orally daily or in divided doses 2 times a day for 10 days; may be increase up to 1,000 mg/day
ER: 775 mg orally daily for 10 days
Age > 12 years:
125 - 250
mg
Orally
every 6-8 hrs
10
days
wt <27 kg: 600,000 U IM daily
wt > 27 kg: 1.2 million U IM daily
30
mg/kg
orally
daily
Indicated for Streptococcal Pharyngitis:
20-30 mg/kg/day orally divided 3 times for Chronic carrier treatment
7 mg/kg/dose 3 times daily for 10 days for Acute treatment
25 - 50
mg/kg
Capsule
Orally
every 8 hrs
10
days
Future Trends
References
https://www.ncbi.nlm.nih.gov/books/NBK544342/
ADVERTISEMENT
» Home » CAD » Infectious Disease » Respiratory Tract Infection » Tonsillitis
The lateral oropharynx contains the palatine or faucial tonsils. The palatine arches or pillars are situated between the palatoglossal arch anteriorly and the palatopharyngeal arch posteriorly. Along with the adenoids (nasopharyngeal tonsil), lingual tonsil, and tubal tonsil, the tonsils are made of lymphatic tissue and make up Waldeyer’s ring.
They act as the initial immunological barrier to insults, offering a crucial line of protection against inhaled or ingested microorganisms. Tonsillitis, or tonsil inflammation, is a typical condition that accounts for 1.3 percent of patient visits.
It usually manifests as a sore throat and is mostly caused by a bacterial or viral infection. A definitive diagnosis is an acute tonsillitis. It might be challenging to distinguish between viral and bacterial causes but doing so is essential to avoid the misuse of antibiotics.
A sore throat is a reason for about 2 percent of ambulatory patient visits in the US. The sickness can happen at any time of the year; however, it is more common in the winter and spring seasons.
15 percent to 30 percent of patients under the age of five and 5 percent to 15 percent of individuals over the age of 15 have GABHS. Patients under five are more likely to experience viral causative agents. In children younger than two years old, GABHS is uncommon.
Tonsillitis typically results from an infection, which could be bacterial or viral. The most frequent causes are viral causes. Common cold-causing viruses such as the respiratory syncytial virus, rhinovirus, coronavirus, and adenovirus are typically the most prevalent viral culprits. Typically, they are not particularly virulent and rarely cause problems.
Tonsillitis can also be brought on by other viruses like Epstein-Barr (which causes mononucleosis), rubella, HIV, hepatitis A, and cytomegalovirus (CMV). GABHS (Group A beta-hemolytic Streptococcus) is the most common cause of bacterial infections; however, Staphylococcus aureus, Haemophilus influenza, and Streptococcus pneumoniae have all been grown.
Pathogens that are both anaerobic and aerobic can cause bacterial tonsillitis. Even so, Corynebacterium diphtheriae, which causes diphtheria, should be considered as an etiology in unvaccinated individuals. HIV, chlamydia, syphilis, and gonorrhea are possible additional causes in people who engage in sexual activity. Clinicians should evaluate their patients’ risks because tuberculosis has also been linked to recurrent tonsillitis.
In the lack of complications, the outcome for acute tonsillitis is very good. The majority of instances are self-limiting illnesses in healthier patient groups, which cure quickly and leave few long-term effects. Even though patients with repeated infections may need surgery, their long-term outcome is still favorable.
Even individuals with problems such as Lemierre syndrome and peritonsillar abscess have great long-term results in the age of antibiotics. The long-term effects of GABHS problems, such as glomerulonephritis and rheumatic fever, can include heart valve disease and impaired kidney function.
In the developed world, these entities are extremely uncommon, and incidence has decreased since penicillin therapy became available. If symptoms don’t get better, a different diagnosis, such as chlamydia, HIV, gonorrhea, TB, syphilis, abscess, Kawasaki illness, Lemierre syndrome, and mononucleosis, should be considered. The underlying illness in these circumstances affects the overall outcome.
500
mg
2 times a day or 1 g daily
10
days
ER: 775 mg daily for 10 days
1.2 million units given IM daily as a single dose
400
mg
Orally
divided in to 2 times a day
10
days
Indicated for Streptococcal pharyngitis:
250 mg oral tablet immediate release twice a day for 14 days
250
mg
Capsule
Orally
every 6 hrs
1
g
orally
daily
10
days
Note: indicated for pharyngitis and tonsillitis caused by Group A beta-hemolytic streptococci
500 mg orally once a day, followed by 250 mg 4 times a day, on the 2nd to 5th day.
125 - 250
mg
Orally
every 8 hrs
10
days
Children and Adolescents: :
50 mg/kg/day orally daily or in divided doses 2 times a day for 10 days; may be increase up to 1,000 mg/day
ER: 775 mg orally daily for 10 days
Age > 12 years:
125 - 250
mg
Orally
every 6-8 hrs
10
days
wt <27 kg: 600,000 U IM daily
wt > 27 kg: 1.2 million U IM daily
30
mg/kg
orally
daily
Indicated for Streptococcal Pharyngitis:
20-30 mg/kg/day orally divided 3 times for Chronic carrier treatment
7 mg/kg/dose 3 times daily for 10 days for Acute treatment
25 - 50
mg/kg
Capsule
Orally
every 8 hrs
10
days
https://www.ncbi.nlm.nih.gov/books/NBK544342/
The lateral oropharynx contains the palatine or faucial tonsils. The palatine arches or pillars are situated between the palatoglossal arch anteriorly and the palatopharyngeal arch posteriorly. Along with the adenoids (nasopharyngeal tonsil), lingual tonsil, and tubal tonsil, the tonsils are made of lymphatic tissue and make up Waldeyer’s ring.
They act as the initial immunological barrier to insults, offering a crucial line of protection against inhaled or ingested microorganisms. Tonsillitis, or tonsil inflammation, is a typical condition that accounts for 1.3 percent of patient visits.
It usually manifests as a sore throat and is mostly caused by a bacterial or viral infection. A definitive diagnosis is an acute tonsillitis. It might be challenging to distinguish between viral and bacterial causes but doing so is essential to avoid the misuse of antibiotics.
A sore throat is a reason for about 2 percent of ambulatory patient visits in the US. The sickness can happen at any time of the year; however, it is more common in the winter and spring seasons.
15 percent to 30 percent of patients under the age of five and 5 percent to 15 percent of individuals over the age of 15 have GABHS. Patients under five are more likely to experience viral causative agents. In children younger than two years old, GABHS is uncommon.
Tonsillitis typically results from an infection, which could be bacterial or viral. The most frequent causes are viral causes. Common cold-causing viruses such as the respiratory syncytial virus, rhinovirus, coronavirus, and adenovirus are typically the most prevalent viral culprits. Typically, they are not particularly virulent and rarely cause problems.
Tonsillitis can also be brought on by other viruses like Epstein-Barr (which causes mononucleosis), rubella, HIV, hepatitis A, and cytomegalovirus (CMV). GABHS (Group A beta-hemolytic Streptococcus) is the most common cause of bacterial infections; however, Staphylococcus aureus, Haemophilus influenza, and Streptococcus pneumoniae have all been grown.
Pathogens that are both anaerobic and aerobic can cause bacterial tonsillitis. Even so, Corynebacterium diphtheriae, which causes diphtheria, should be considered as an etiology in unvaccinated individuals. HIV, chlamydia, syphilis, and gonorrhea are possible additional causes in people who engage in sexual activity. Clinicians should evaluate their patients’ risks because tuberculosis has also been linked to recurrent tonsillitis.
In the lack of complications, the outcome for acute tonsillitis is very good. The majority of instances are self-limiting illnesses in healthier patient groups, which cure quickly and leave few long-term effects. Even though patients with repeated infections may need surgery, their long-term outcome is still favorable.
Even individuals with problems such as Lemierre syndrome and peritonsillar abscess have great long-term results in the age of antibiotics. The long-term effects of GABHS problems, such as glomerulonephritis and rheumatic fever, can include heart valve disease and impaired kidney function.
In the developed world, these entities are extremely uncommon, and incidence has decreased since penicillin therapy became available. If symptoms don’t get better, a different diagnosis, such as chlamydia, HIV, gonorrhea, TB, syphilis, abscess, Kawasaki illness, Lemierre syndrome, and mononucleosis, should be considered. The underlying illness in these circumstances affects the overall outcome.
https://www.ncbi.nlm.nih.gov/books/NBK544342/
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
USA – BOSTON
60 Roberts Drive, Suite 313
North Adams, MA 01247
INDIA – PUNE
7, Shree Krishna, 2nd Floor, Opp Kiosk Koffee, Shirole Lane, Off FC Road, Pune 411004, Maharashtra
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.