A Framework for Fitness-for-Purpose and Reuse in Computational Phenotyping
November 17, 2025
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
chlorpheniramine and phenylephrine
1
Tablet
Orally
every 4 hrs
Do not exceed 6 tablets per day
or
5 mL orally every 4-6 hours
Do not exceed 30 mL per day
1.2 million units given IM per day as a single dose
promethazine/dextromethorphanÂ
Indicated for cough:
5ml(6.25mg/15mg) orally every 4 to 6 hours when necessary
Maximum dose-30ml for 24 hours
Mild-moderate
Depending on the type and infection severity, take 200-400 mg two times a day for around 7-10 days by oral route
Indicated for upper respiratory tract infections
In vivo, data suggests taking 500 mg orally four times a day
The treatment duration is five days
Indicated for upper respiratory tract infections
In vivo, data suggests taking 500 mg orally four times a day
The treatment duration is five days
Initial dose of 200 mg intravenously on day 1 and given in 1 infusion or 2 infusions
Maximum dose: 100 mg to 200 mg per day intravenously
Initial dose of 200 mg orally on day 1 and given in 2 doses – 100 mg for every 12 hours
Maximum dose: 100 mg once a day orally or 50 mg for every 12 hours orally
Mild/Moderate/ Severe: A dose of 400-800 mg orally given per day in every 12hrs for about 7-10 days
Moreover, in the US the drug bacampicillin is no longer used and marketed
chlorpheniramine and phenylephrine
Liquid (drops)
Age: 2-6 years
1 mL orally every 4-6 hours.
Do not exceed 4mL per day
Age: 6-12 years
2 mL orally every 4-6 hours.
Do not exceed 4mL per day
Age: >12 years
4 mL orally every 4-6 hours.
Do not exceed 4mL per day
Liquid
Age: >12 years
5 mL orally every 4-6 hours.
Do not exceed 30 mL per day
tablet
Age: >12 years
1 tablet orally every 4-6 hours.
Do not exceed 6 tablets per day
promethazine/dextromethorphanÂ
Indicated for cough:
<2 years: Safety and efficacy not established
2-6 years: 1.25 to 2.5 mL orally every 4 to 6 hours; a maximum daily dose of 12.5 mg/30 mg (10 mL)
6-12 years: Up to 25 mg/60 mg (20 mL) in 24 hours with 2.5 to 5 mL orally every 4 to 6 hours
>12 years: 6.25 mg/15 mg (5 mL) orally every 4 to 6 hours as needed; maximum of 30 mL/24 hours
Future Trends
References

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