Insurance Can Decide Survival for Young Cancer Patients
April 2, 2026
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Aconitum, Monkshood
Synonyms :
aconite
Class :
Analgesics, herbals
Brand Name :
Aconitum, Monkshood
Synonyms :
aconite
Class :
Analgesics, herbals
Actions and Spectrum:
The action of aconite on the body includes:
analgesic: aconite has been traditionally used to relieve pain, especially in conditions such as neuralgia, arthritis, and toothache.
anti-inflammatory: aconite has been shown to have anti-inflammatory effects and can be used to treat conditions such as rheumatoid arthritis and gout.
cardiac stimulant: aconite can increase heart rate and strengthen the heart’s contractions. It has been used to treat heart failure and other heart-related conditions.
Vasodilator: aconite can dilate blood vessels and improve blood flow. It can be used to treat conditions such as Raynaud’s disease and angina.
antipyretic: aconite has been used to reduce fever.
The spectrum of aconite includes its use in the treatment of:
Pain: aconite is traditionally used to relieve pain, especially in conditions such as neuralgia, arthritis, and toothache.
Inflammation: aconite has been shown to have anti-inflammatory effects and can be used to treat conditions such as rheumatoid arthritis and gout.
Heart conditions: aconite can increase heart rate and strengthen the heart’s contractions. It has been used to treat heart failure and other heart-related conditions.
Circulatory disorders: aconite can dilate blood vessels and improve blood flow. It can be used to treat conditions such as Raynaud’s disease and angina.
Fever: aconite has been used to reduce fever.
Frequency not defined
V-TACH, V-FIB; LIFE THREATENING WITHIN 30 MINUTES OF INGESTION
Hypokalemia
Weakness
Dizziness
Acidosis
Contraindication/Caution:
Pregnancy and breastfeeding: aconite should not be used during pregnancy or breastfeeding as it can cause uterine contractions and harm the developing fetus.
Heart conditions: aconite should not be used in individuals with heart conditions, as it can cause arrhythmias and other cardiac problems.
Hypertension: aconite can increase blood pressure and should not be used by individuals with hypertension.
Liver and kidney diseases: aconite is metabolized in the liver and excreted through the kidneys, so it should be avoided in individuals with liver or kidney diseases.
Children: aconite should not be used in children, as they are more sensitive to its toxic effects.
Alcohol consumption: aconite should not be used with alcohol, as it can increase the risk of toxicity.
Pregnancy warnings:
Pregnancy category: N/A
Lactation: Excreted into human milk is unknown
Pregnancy Categories:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
aconite, also known as aconitum napellus, is a plant that has been used for medicinal purposes for centuries. The pharmacology of aconite is complex and involves several active compounds, including aconitine, mesaconitine, and hypaconitine.
Pharmacodynamics Mechanism:
The pharmacodynamic mechanism of aconite involves its ability to block the inactivation of voltage-gated sodium channels, resulting in a prolonged activation of the channels and an increase in the release of neurotransmitters, such as norepinephrine and dopamine. This increase in neurotransmitter release leads to a reduction in pain and inflammation by inhibiting the transmission of pain signals in the nervous system.
Mechanism of Action:
The mechanism of action of aconite is primarily through the interaction with voltage-gated sodium channels in nerve and muscle cells. aconitine, the primary alkaloid in aconite, binds to the sodium channels and enhances their activation, resulting in an increased influx of sodium ions into the cells. This depolarizes the cells and leads to an increase in action potential firing.
Pharmacokinetics:
Absorption
aconite alkaloids can be absorbed through the skin, mucous membranes, and gastrointestinal tract. They are rapidly absorbed and can reach peak concentrations in the bloodstream within a few hours of exposure.
Distribution
aconite alkaloids are distributed throughout the body, with the highest concentrations found in the liver, kidneys, and heart. They can also cross the blood-brain barrier and affect the central nervous system.
Metabolism
aconite alkaloids are primarily metabolized in the liver by cytochrome P450 enzymes. The primary metabolites are aconitine and mesaconitine, which are less toxic than the parent compounds.
Excretion and elimination
aconite alkaloids and their metabolites are eliminated from the body primarily via the kidneys. The half-life of aconite alkaloids is relatively short, with a range of 2-6 hours depending on the specific alkaloid and the route of exposure.
Administration:
Dosage: The recommended dosage for aconite depends on the specific preparation being used. It is important to follow the dosage instructions on the product label or as prescribed by a healthcare provider.
Form of administration: aconite is available in various forms, including tinctures, tablets, and creams. The form of administration should be chosen based on the intended use and the condition being treated.
Patient information leaflet
Generic Name: aconite
Why do we use aconite ?
aconite, also known as monkshood, is a plant that has been used for medicinal purposes for centuries. The root of the plant contains several active compounds, including aconitine, which has analgesic and anti-inflammatory properties.
aconite is primarily used in traditional Chinese medicine to treat a variety of conditions, including pain, inflammation, fever, and respiratory infections. It is also used topically to treat skin conditions such as eczema and psoriasis.
In Western medicine, aconite is sometimes used as a homeopathic remedy for conditions such as anxiety, insomnia, and heart palpitations. However, the use of aconite in Western medicine is controversial, as it can be toxic if not used properly.
It is important to note that aconite should only be used under the guidance of a qualified healthcare professional, as it can have serious side effects if not used properly.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
