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December 25, 2025
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Brand Name :
Gelusil, Milantex, Almacone, Mag-al Plus
Synonyms :
aluminium hydroxide/magnesium hydroxide/simethicone
Class :
Antacids
Brand Name :
Gelusil, Milantex, Almacone, Mag-al Plus
Synonyms :
aluminium hydroxide/magnesium hydroxide/simethicone
Class :
Antacids
Dosage Forms & Strengths
Suspension
(400mg/400mg/40mg)/5ml
(aluminium hydroxide/magnesium hydroxide/simethicone)/5ml
Tablet
200mg/200mg/25mg
(aluminium hydroxide/magnesium hydroxide/simethicone)
Take two to four tablets orally every four to six hours for 2 weeks
Not more than 12 tablets in a day
Take 10 to 20 ml of oral suspension four times daily
Not more than 80 ml in a day
Dosage Forms & Strengths
Suspension
(400mg/400mg/40mg)/5ml
(aluminium hydroxide/magnesium hydroxide/simethicone)/5ml
Tablet
200mg/200mg/25mg
(aluminium hydroxide/magnesium hydroxide/simethicone)
For <12 years old: Safety and efficacy not established
For >12 years old:
Take two to four tablets orally every four to six hours for 2 weeks
For <12 years old: Safety and efficacy not established
For >12 years old:
Take 10 ml to 20 ml of oral suspension four times a daily
Magnesium hydroxide, aluminium hydroxide and simethicone is a combination drug used as antacids to alleviate symptoms of indigestion, heartburn, and acid reflux.
Frequency not defined
Constipation
Anaphylactic reaction
Pruritis
Black box warning:
None
Contraindications/caution:
Contraindications:
Hypersensitivity
Cautions:
Caution in Renal Failure
Avoid Use for Hyperphosphatemia
Pregnancy Warnings:
Pregnancy category: C
Lactation: Excretion of the drug into the human breast milk is unknown
Pregnancy categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
Aluminium hydroxide is an antacid, so they neutralize gastric acid.
Magnesium hydroxide is an alkaline compound thus it interacts with hydrochloric acid in the stomach.
Simeticone is an anti-foaming agent which reduces the surface tension of gas bubbles.
Pharmacodynamics
Limited information is available.
Pharmacokinetics:
Limited information is available on ADME.
Administration:
Take this combination drug orally in form of suspension, liquid and tablet.
Patient information leaflet
Generic Name: aluminium hydroxide/magnesium hydroxide/ simethicone
Why do we use aluminium hydroxide/magnesium hydroxide/ simethicone?
Aluminium hydroxide and magnesium hydroxide work as antacids to alleviate symptoms like heartburn and acid indigestion.
Simethicone helps in reducing bloating to provide relief from discomfort caused by gas accumulation.
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