Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
ORAFLEX
Synonyms :
benoxaprofen (discontinued)
Class :
 Anti-inflammatory drug 
Brand Name :
ORAFLEX
Synonyms :
benoxaprofen (discontinued)
Class :
 Anti-inflammatory drug 
Dosage forms and strengthsÂ
Oral tabletÂ
600 mgÂ
800 mgÂ
Take 600 mg a day orally
In some cases the dose may be elevated to 800 mg
Take 600 mg a day orally
In some cases the dose may be elevated to 800 mg
Not indicatedÂ
Refer adult dosingÂ
the risk of bleeding can be raised when benoxaprofen is combined with sulfinpyrazone
the severity of hypertension may be increased
Action and SpectrumÂ
It relieves pain and inflammation by blocking the production of prostaglandins, which are chemicals that promote these symptoms. It is used to treat osteoarthritis and rheumatoid arthritis, but it is discontinued due to severe side effects.Â
Frequency not definedÂ
Urinary urgencyÂ
Blurred visionÂ
EpistaxisÂ
PalpitationsÂ
HeadacheÂ
DizzinessÂ
FaintnessÂ
Black Box Warning:Â Â
None
Contraindication/Caution:Â
HypersensitivityÂ
Renal impairmentÂ
Hepatic impairmentÂ
Pregnancy warnings:    Â
Pregnancy category: N/AÂ
Lactation: Excreted into human milk is unknownÂ
Pregnancy Categories:        Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.Â
Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
PharmacologyÂ
It is used for ain-relieving, anti-swelling, and fever-reducing abilities, belongs to the category of non-steroidal anti-inflammatory drugs.Â
PharmacodynamicsÂ
It inhibits the cyclooxygenase activity which is responsible for the synthesis of prostaglandins.Â
PharmacokineticsÂ
AbsorptionÂ
Limited data availableÂ
DistributionÂ
Limited data availableÂ
MetabolismÂ
Limited data availableÂ
Elimination/ExcretionÂ
Limited data availableÂ
AdministrationÂ
It is administered orally in the form of tablets or capsules.Â
Patient information leafletÂ
Generic Name: benoxaprofen (discontinued)Â
Why do we use benoxaprofen (discontinued)?Â
IT is used treat pain and inflammation associated with Osteoarthritis and Rheumatoid arthritis.Â
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