- March 15, 2022
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Brand Name :
Casodex
Synonyms :
Bicalutamide
Class :
Antineoplastics, Antiandrogen;
Dosage Forms & Strengths
tablet
50mg
When bicalutamide is combined with an LHRH analog:
50
mg
Orally
once a day
Dose Adjustments
Renal Dose Adjustments
No adjustment required
Liver Dose Adjustments
Caution recommended.
When both drugs are combined, there may be an increased effect of flibanserin by affecting hepatic or intestinal enzyme CYP3A4 metabolism
when both drugs are combined, there may be an increased effect of Lomitapide by affecting hepatic or intestinal enzyme CYP3A4 metabolism
when both drugs are combined, there may be an increased effect of Lonafarnib by affecting hepatic or intestinal enzyme CYP3A4 metabolism
When both drugs are combined, there may be an increased risk of adverse effect
when both drugs are combined, there may be an increased risk of adverse effect
when both drugs are combined, there may be an increased risk of adverse effect
when both drugs are combined, there may be an increased risk of adverse effect
may enhance cisapride's serum concentration
It may enhance the levels when combined with tamsulosin by affecting CYP3A4 metabolism
It may diminish its effectiveness when combined with flotufolastat F-18
when both drugs combine bicalutamide will increase effect of ifosfamide by affecting the enzyme CYP3A4 metabolism.
when both drugs are combined, there may be an increased metabolism of bicalutamide
increases serum level of cabazitaxel by affecting the enzyme CYP3A4
it increases the effect or level of palbociclib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
may increase the hypertensive effect of hypertension-associated agents
Adverse drug reaction
Frequency defined
>10%
Abdominal pain
Anemia
Hot flashes
General pain
Back pain
Asthenia
Dyspnea
Edema
Peripheral edema
Diarrhea
Hematuria
Nocturia
1-10%
Headache
LFTs elevation
Weight loss
Anorexia
Gynecomastia
Rash
UTI
Chest pain
Hypertension
Vomiting
Flu like symptoms
Contraindicated:
lomitapide
lonafarnib
Pregnancy warnings:
Breastfeeding warnings:
Pregnancy Categories:
Patient Information Leaflet
Generic Name: Bicalutamide (Rx)
Pronounced: bi-ca-lu-tamide
Why do we use Bicalutamide?
Bicalutamide is an anticancer drug used to treat prostate cancer and is also helpful in other conditions associated with it
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