Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Biktarvy
Synonyms :
bictegravir
Class :
Antiviral agents
Brand Name :
Biktarvy
Synonyms :
bictegravir
Class :
Antiviral agents
Dosage Forms & StrengthsÂ
TabletÂ
50 mgÂ
one tablet containing 50 mg bictegravir, 200 mg emtricitabine, and 25 mg tenofovir alafenamide administered once a day with or without food
Dosage Forms & StrengthsÂ
TabletÂ
50 mgÂ
Above 14 kg to below 25 kg: 1 tablet containing 30 mg bictegravir, 120 mg emtricitabine, and 15 mg tenofovir alafenamide administered once a day with or without food
Refer adult dosingÂ
may diminish the serum concentration of primidone
may diminish concentration of serum when combined with bictegravir
may diminish concentration of serum when combined with bictegravir
may diminish concentration of serum when combined with bictegravir
may diminish concentration of serum when combined with bictegravir
bictegravir: they may diminish the serum concentration of calcium salts
bictegravir: they may diminish the serum concentration of calcium salts
bictegravir: they may diminish the serum concentration of calcium salts
bictegravir: they may diminish the serum concentration of calcium salts
bictegravir: they may diminish the serum concentration of calcium salts
bictegravir: they may decrease the therapeutic effect of antacids
bictegravir: they may decrease the therapeutic effect of antacids
bictegravir: they may decrease the therapeutic effect of antacids
bictegravir: they may decrease the therapeutic effect of antacids
bictegravir: they may decrease the therapeutic effect of antacids
Sucralfate may reduce the serum concentration of bictegravir
may diminish the serum concentration of iron preparations
may diminish the serum concentration of polyvalent cation-containing products
may diminish the serum concentration of Polyvalent Cation Containing Products
may diminish the serum concentration when combined
CYP3A strong enhancers of the small intestine may reduce the bioavailability of bictegravir
rifabutin: they may diminish the serum concentration of bictegravir
When bictegravir is used together with fluconazole, this leads to reduction in the bictegravir metabolism
When bictegravir is used together with adenine, this leads to a reduction in the bictegravir's metabolism
Action and Spectrum:Â
Bictegravir is an anti-viral drug that unboosts the HIV integrase strand transfer inhibitor through 10 day therapy given in a single dose daily.Â
NoneÂ
NoneÂ
Contraindication/Caution:Â
HypersensitivityÂ
Pregnancy Warnings:Â
Pregnancy category: Insufficient data availableÂ
Lactation:Â
Excretion of the drug in human breast milk is unknownÂ
Pregnancy Categories:Â
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the 1st trimester or 2nd trimester.Â
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.Â
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.Â
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology:Â
Bictegravir is an anti-viral drug that unboosts the HIV integrase strand transfer inhibitor through 10 day therapy given in a single dose daily. It is well tolerated in patients who have not been treated with previous antiviral medications.Â
Pharmacodynamics:Â
Its main action is to inhibit the integrase enzyme activity and there by helps in preventing the entry of HIV 1 in to host cells and also inhibits the c HIV 1 provirus conversion and its replication.Â
Pharmacokinetics:Â
AbsorptionÂ
It is rapidly absorbed.Â
DistributionÂ
0.2 l/kg indicates the volume of distribution.Â
MetabolismÂ
It involves renal and hepatic metabolismÂ
ExcretionÂ
The metabolites mainly excreted through the urineÂ
AdministrationÂ
administered orally for 10 days.Â
for missed dose or overdose contact physician.Â
Patient information leafletÂ
Generic Name: bictegravirÂ
Pronounced: (bye-tek-GRAY-veer)Â
Why do we use bictegravirÂ
Bictegravir is an aniviral drug which blocks the activity of HIV virus and prevents it entering the host. It is also available in the form of combination with other antiviral drugs which have more effectiveness when compared to monotherapy.Â
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