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Brand Name :
Not available
Synonyms :
ambufylline
Class :
Antiasthmatic, COPD preparations
Dosage Forms & Strengths
Data not available
Refer to adult dosing
when combined with abametapir, the serum levels of bufylline can be enhanced
the rate of excretion of bufylline can be increased with acetazolamide
when combined with acyclovir, metabolism of bufylline may be reduced
when combined with benzocaine, metabolism of bufylline may be reduced
serum levels of bufylline can be reduced with butabarbital
when combined with carmustine, metabolism of bufylline may be reduced
when combined with rucaparib, metabolism of bufylline may be increased
when combined with ropivacaine, metabolism of bufylline may be reduced
the excretory rate of bufylline may be increased by riluzole
when combined with rosoxacin, metabolism of bufylline may be reduced
when combined with zotepine, metabolism of bufylline may be reduced
the excretory rate of bufylline may be increased by zaleplon
Actions and spectrum:
Bufylline is a derivative of theophylline
Frequency not defined
Irritation of the gastro intestinal tract
Stimulation of the central nervous system
Restlessness
Tremor
Headache
Palpitation
Black Box Warning
To be used with caution in patients with epilepsy and disorders of digestive tract
Contraindication/Caution:
Contraindication:
Hypersensitivity
Peptic ulcers
Liver failure
Cardiac arrythmia
Epilepsy
Pregnancy consideration:
Safety and efficacy study not established
Lactation:
Safety and efficacy study not established
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the foetus `in either the first or second trimester.
Category B: There were a lack of studies on pregnant women and no evidence of risk to the foetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Limited data available
Pharmacodynamics:
Pharmacokinetics:
Absorption
Distribution
Metabolism
Elimination and excretion
Half life:
Administration:
Patient information leaflet
Generic Name: bufylline
Why do we use bufylline?
Bufylline is to relieve respiratory disorders such as cough, asthma. It is also used in the treatment of COPD such as bronchitis, emphysema. Bufylline also facilitates the smooth flow of blood due to its vasodilation property