Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Brand Name :
Neo-Calglucon,Calcionate,Calciquid
Synonyms :
calcium glubionate
Class :
Minerals and Electrolytes
Dosage forms and strengths Â
SyrupÂ
 (1.8 g/5 mL)Â
oral intake of 15 mL three times daily, preferably before meals
It is important to note that each 5 mL of the medication supplies 115 mg of elemental calcium
In addition to the calcium supplementation, treatment may also involve the oral administration of vitamin D
The recommended oral administration is 5 to 15 mL, to be taken three times daily, preferably before meals
Additionally, the treatment protocol for this condition may include the supplementation of vitamin D
Administration of the medication is recommended orally, with a suggested dosage range of 5 to 15 mL to be taken once daily prior to the morning meal
Therapeutic approach for managing the disease may also incorporate the utilization of vitamin D as an adjunctive therapy
The recommended administration for this medication is oral intake of 15 mL, to be taken one to three times daily prior to meals
oral ingestion of a volume ranging from 5 to 10 mL, to be taken three times daily prior to meal consumption
In addition to this regimen, the therapeutic approach may include the supplementation of vitamin D
Dosage forms and strengthsÂ
Syrup Â
(1.8 g/5 mL)Â
Neonatal
Oral:
The recommended adequate intake (AI) for elemental calcium is 200 mg per day
It is important to note that individual requirements may differ based on factors such as prematurity, postnatal age, and other clinical consideration
Close monitoring of serum calcium concentrations is advised to determine the precise needs of each patient
The recommended dosage for elemental calcium is 50 to 150 mg/kg/day, administered in four to six doses divided
The daily dose should not exceed more than 1 grams
For calcium glubionate, the recommended dosage is 1200 mg/kg/day, also given in four to six dose divided
Dosing
Usual Oral
Adequate intake
for first to six months-Administer the dosage of 200 mg/day
for seven to twelve months- Administer the dosage of 260 mg/day
Recommended daily allowance
for Age one to three years- Administer the dosage of 700 mg/day
for Age four to eight years- Administer the dosage of 1000 mg/day
for Age nine to eighteen years- Administer the dosage of 1300 mg/day
Dietary supplement
Dosage based on product containing-(1.8 g calcium glubionate/5 mL)
Infants (less than 12 months):
The recommended dosage for infants below the age of 12 months is one teaspoonful to be administered five times a day
It is permissible to mix the medication with juice or formula to facilitate administration
Children (less than four years)- The recommended dosage is two teaspoonfuls to be administered three times daily
Children (four years and older) and Adolescents:
The recommended dosage is one tablespoonful to be administered three times daily
Hypocalcemia Expressed in (mg) of elemental calcium:
Dosage Recommendation for Children:
The recommended dosage for children is 45 to 65 mg/kg/day, administered in four equally divided doses throughout the day
Expressed in (mg) of calcium glubionate
Dosage for infants and children should be administered at a range of 600 to 2000 mg/kg/day, divided into four equal doses
The daily dose should not exceed more than 9 grams
Daily maintenance calcium: (IV)
For infants and children weighing less than 25 kg, The recommended dosage is 1 to 2 mEq/kg/day
In the case of children weighing between 25 and 45 kg, The dosage range is 0.5 to 1.5 mEq/kg/day
For children weighing over 45 kg and adults, the recommended dosage is either 10 to 20 mEq/kg/day or 0.2 to 0.3 mEq/kg/day
Refer adult dosingÂ
anhydrous combining calcipotriol with calcium glubionate anhydrous may boost the risk or intensity of adverse effects
anhydrous the risk or magnitude of adverse effects can be heightened when tacalcitol is correlated with calcium glubionate anhydrous
when cholecalciferol is combined with calcium glubionate anhydrous, the chances of adverse effects may increase
Actions and Spectrum:Â
Action:Â
Calcium Supplement: calcium glubionate works as a calcium supplement, providing the body with additional calcium ions. Calcium is crucial for various processes in the body, including bone formation, muscle contraction, nerve transmission, and blood clotting. Â
Spectrum:Â
Calcium Deficiency: calcium glubionate is primarily prescribed for individuals with a calcium deficiency or at risk of developing one. This includes people with conditions such as osteoporosis (reduced bone density), osteomalacia (softening of bones), hypoparathyroidism (decreased parathyroid hormone production), and certain renal disorders.Â
Frequency not defined Â
Increased urinationÂ
dry mouth or increased thirstÂ
constipationÂ
decreased appetiteÂ
nausea or vomitingÂ
Black Box Warning:Â
None
Contraindication/Caution:Â Â
Hypercalcemia: calcium supplements should not be used in individuals with high levels of calcium in their blood, as it can lead to further elevation of calcium levels and potentially result in adverse effects.Â
Hypercalciuria: People with excessive urinary excretion of calcium may be at increased risk of developing kidney stones. Therefore, calcium supplements may be contraindicated in individuals with hypercalciuria.Â
Hypersensitivity: If an individual has a known hypersensitivity or allergic reaction to calcium or any of the ingredients in the specific calcium supplement formulation, its use should be avoided.Â
Calcium-based kidney stones: calcium supplements may increase the risk of calcium-based kidney stones in susceptible individuals. Therefore, caution should be exercised in those with a history of kidney stones.Â
Certain medical conditions: People with certain medical conditions, such as hyperparathyroidism, sarcoidosis, or certain types of cancer, may have altered calcium metabolism and should consult with a healthcare professional before taking calcium supplements.Â
Pregnancy warnings:    Â
Pregnancy category: N/AÂ
Lactation: Excreted into human milk is unknownÂ
Pregnancy Categories:        Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.Â
Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
Pharmacology:Â Â
calcium glubionate is a medication that belongs to the class of drugs known as calcium supplements.Â
Pharmacodynamics:Â Â
calcium glubionate works by providing supplemental calcium ions, which are essential for various physiological processes in the body. calcium is an important mineral involved in muscle contraction, nerve function, blood clotting, and maintaining the integrity of bones and teeth.  Â
Pharmacokinetics:Â
AbsorptionÂ
calcium glubionate is an oral formulation, typically administered as a liquid. It is absorbed in the gastrointestinal tract upon ingestion, primarily in the small intestine. calcium absorption is an active process that involves the interaction with vitamin D and calcium-binding proteins.Â
DistributionÂ
Once absorbed, calcium ions from calcium glubionate are transported via the bloodstream to various tissues and organs in the body. calcium is essential for numerous physiological functions and is distributed widely, with significant amounts found in bones, teeth, and soft tissues.Â
MetabolismÂ
calcium glubionate is not metabolized in the body. It is primarily a source of calcium ions that can participate in various biochemical reactions, including bone formation, muscle contraction, nerve signaling, and blood clotting. The body regulates calcium levels through mechanisms involving parathyroid hormone (PTH), calcitonin, and vitamin D.Â
Excretion and EliminationÂ
calcium ions are excreted mainly through feces and urine. The excretion of calcium is regulated by the kidneys, which reabsorb or excrete calcium based on the body’s needs. When calcium levels are high, the kidneys increase its excretion in the urine, while low levels lead to increased reabsorption.Â
Administration: Â
Dosage: The appropriate dosage of calcium glubionate varies depending on the individual’s age, medical condition, and the severity of the calcium deficiency. Based on these factors, a healthcare professional, such as a doctor or pharmacist, will determine the dosage.Â
Oral Route: calcium glubionate is usually administered orally, which means it is taken by mouth. It is available in liquid form, making measuring and administering the correct dose easier. The liquid formulation allows for better absorption in the digestive system.Â
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Patient information leafletÂ
Generic Name: calcium glubionateÂ
Why do we use calcium glubionate? Â
Calcium Supplementation: calcium glubionate is commonly prescribed to individuals who have low levels of calcium in their blood or are at risk of developing calcium deficiency. It helps increase the levels of calcium in the body, which is essential for various physiological processes, including bone health, muscle function, nerve transmission, and blood clotting.Â
Osteoporosis: calcium glubionate may be prescribed as part of a comprehensive treatment plan for individuals with osteoporosis. Â
Pregnancy and Breastfeeding: A woman’s calcium requirements increase during pregnancy and breastfeeding. calcium glubionate may be recommended to ensure an adequate supply of calcium for the developing fetus or to support milk production during breastfeeding. Pregnant and breastfeeding women need to meet their calcium needs to support the growth and development of the baby and maintain their own bone health.Â
Hypocalcemia: calcium glubionate can be used to raise calcium levels in individuals with hypocalcemia, which may occur due to various reasons, such as certain medical conditions, vitamin D deficiency, or as a side effect of certain medications.Â
Hyperphosphatemia: calcium glubionate can also be used to manage elevated levels of phosphorus in the blood, a condition known as hyperphosphatemia. It works by binding to phosphorus in the gastrointestinal tract, reducing its absorption and promoting its excretion from the body. This helps normalize phosphorus levels in individuals with kidney dysfunction or other conditions that cause excessive phosphorus buildup.Â