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Brand Name :
Radian B
Synonyms :
camphor/camphor oil white/capsicum oleoresin /menthol/methyl salicylate
Class :
Analgesic, Anti-inflammatory agent
Dosage Forms & Strengths
Cream
40 gm
100 gm
Dosage Forms & Strengths
Cream
40 gm
100 gm
Refer to adult dosing
Actions and Spectrum
This combination medicine which provides a cooling or warming sensation to the skin when applied topically. These ingredients can help relax tense muscles and alleviate muscle soreness.
The ingredients like menthol and methyl salicylate possess mild analgesic properties. It can help reduce pain and discomfort associated with muscle aches, strains, and minor injuries.
Frequency not defined
Contact dermatitis
Headache
Skin rash, flushing
Eczema
Black Box Warning
None
Contraindication/Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
Menthol produces a cooling sensation by activating cold-sensitive receptors in the skin.
Methyl salicylate has analgesic and anti-inflammatory properties.
Capsicum works by binding to and activating transient receptor potential vanilloid 1 receptor in the skin.
Pharmacodynamics
Camphor acts as a topical analgesic. It works by desensitizing sensory nerve endings in the skin.
Capsicum oleoresin’s analgesic effects help to alleviate pain and discomfort by reducing the sensitivity of nerves in the affected area.
Pharmacokinetics
Absorption
It absorbed locally into the underlying tissues and bloodstream.
Distribution
It is distributed throughout the body.
Metabolism
It may undergo metabolism in the liver.
Elimination and excretion
It may be excreted from the body via the kidneys.
Administration
It is applied directly to the skin in the form of cream.
Patient information leaflet
Generic Name: camphor/camphor oil white/capsicum oleoresin /menthol/methyl salicylate
Why do we use camphor/camphor oil white/capsicum oleoresin /menthol/methyl salicylate?
This combination drug (Radian B) is applied topically to provide relief from muscle tension, soreness, and stiffness.
Athletes and sports persons may use this cream to help recover from sports-related injuries such as strains, muscle pulls and sprains.
It is also used to relieve back pain in form of discomfort associated with muscle spasms and poor posture.