Alcohol Consumption Emerges as a Key Risk Factor for Buccal Cancer in India
December 24, 2025
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Brand Name :
Dologen, Dologesic
Synonyms :
dexbrompheniramine
Class :
Antihistamines and Antiallergics
Brand Name :
Dologen, Dologesic
Synonyms :
dexbrompheniramine
Class :
Antihistamines and Antiallergics
Dosage Forms & Strengths
Tablet
1 mg
2 mg
Take a dose of 2 mg in combination with pseudoephedrine up to four times a day
Dosage Forms & Strengths
Tablet
1 mg
2 mg
For >6 years old:
Take a dose of 1 mg in combination with pseudoephedrine up to four times a day
Refer to adult dosing
CNS stimulants: they may increase the CNS depressant effect of antihistamines
CNS stimulants: they may increase the CNS depressant effect of antihistamines
CNS stimulants: they may increase the CNS depressant effect of antihistamines
The Therapeutic efficacy of pitolisant may be reduced by antihistamines
tiotropium: they may decrease the therapeutic effect of antihistamines
it may enhance the risk of cns depression when combined with aripiprazole lauroxil
The potential for increased CNS depression risk or seriousness occurs when dexbrompheniramine is used together with pinazepam
when ajmaline is used together with dexbrompheniramine, the risk or seriousness of QTc prolongation is enhanced
The potential for increased CNS depression risk or seriousness occurs when dexbrompheniramine is used together with pipecuronium
When dexbrompheniramine is used together with medazepam, the risk or seriousness of CNS depression is enhanced
When dexbrompheniramine is used together with niaprazine, the risk or seriousness of CNS depression is enhanced
When dexbrompheniramine is used together with levosulpiride, the risk or seriousness of CNS depression is enhanced
When chlordiazepoxide is used together with dexbrompheniramine, this leads to enhanced risk or seriousness of CNS depression
When dexbrompheniramine is used together with melitracen, this leads to enhanced risk or seriousness of CNS depression
When ponesimod is used together with dexbrompheniramine, this leads to enhanced risk or seriousness of bradycardia
When dexbrompheniramine is used together with adenosine, this leads to enhanced risk or seriousness of QTc prolongation
When dexbrompheniramine is used together with givinostat, this leads to enhanced risk or seriousness of Qtc prolongation
When emylcamate is used together with dexbrompheniramine, this leads to enhanced risk or seriousness of CNS depression
When acepromazine is used together with dexbrompheniramine, this leads to enhanced risk or seriousness of CNS depression
hyaluronidase: they may decrease the therapeutic effect of antihistamines
betahistine's therapeutic efficacy may be reduced by antihistamines
Itopride therapeutic efficacy may be reduced by antihistamines
sodium hyaluronate: they may diminish the therapeutic effect of antihistamines
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
Actions and Spectrum
dexbrompheniramine is an H1 receptor antagonist. It competes with histamine for binding to H1 receptors on target cells in the body. dexbrompheniramine blocks the actions of histamine, preventing or alleviating the symptoms of an allergic reaction.
Frequency not defined
Seizure
Drowsiness
Dry mouth, nose
Easy bruising or bleeding
Unusual weakness
Feeling short of breath
Fast or uneven heart rate
Mood changes
Tremor
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: C
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
dexbrompheniramine is an H1 histamine receptor antagonist. It competes with histamine for binding to H1 receptors found on various cells throughout the body, including those in the respiratory tract, blood vessels, and skin.
Pharmacodynamics
dexbrompheniramine counteract the effects of histamine release in response to allergens. It reduces or alleviates the symptoms of allergic reactions, such as those associated with hay fever and allergic conjunctivitis.
Pharmacokinetics
Absorption
dexbrompheniramine is well-absorbed from the gastrointestinal tract when taken orally.
Distribution
dexbrompheniramine is distributed throughout the body.
Metabolism
dexbrompheniramine is metabolized in the liver.
Elimination and excretion
dexbrompheniramine is excreted through the kidneys in the urine.
Administration
dexbrompheniramine is taken orally and is available in tablet form.
Patient information leaflet
Generic Name: dexbrompheniramine
Why do we use dexbrompheniramine?
dexbrompheniramine used to provide relief from allergy-related symptoms.
dexbrompheniramine is used to reduce itching and redness of the eyes associated with allergic conjunctivitis.
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