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Brand Name :
No Data Available.
Synonyms :
Dopamine, Dopamina, 3-Hydroxytyramine, Dopaminum, Oxytyramine
Class :
Adrenergic agonists and pressor agents
Brand Name :
No Data Available.
Synonyms :
Dopamine, Dopamina, 3-Hydroxytyramine, Dopaminum, Oxytyramine
Class :
Adrenergic agonists and pressor agents
Dosage Forms & Strengths
Solution-IV
0.8 mg/mL
1.6 mg/mL
3.2 mg/mL
40 mg/mL
Solution-IV (as hydrochloride)
40 mg/ml
Indicated for treating heart problems and imbalances in shock caused by infections, injuries, septicemia, surgery, kidney issues, or heart failure
continuous infusion:
Initial dose: 2-10 mcg/kg/min intravenously (IV)
Maintenance dose: 2-50 mcg/kg/min intravenously (IV)
Congestive Heart Failure (CHF)
Indicated for treating heart problems and imbalances in shock caused by infections, injuries, septicemia, surgery, kidney issues, or heart failure
continuous infusion:
Initial dose: 2-10 mcg/kg/min intravenously (IV)
Maintenance dose: 2-50 mcg/kg/min intravenously (IV)
Indicated for treating heart problems and imbalances in shock caused by infections, injuries, septicemia, surgery, kidney issues, or heart failure
Continuous infusion:
Initial dose: 2-10 mcg/kg/min intravenously (IV)
Maintenance dose: 2-50 mcg/kg/min intravenously (IV)
Indicated for treating heart problems and imbalances in shock caused by infections, injuries, septicemia, surgery, kidney issues, or heart failure
Continuous infusion:
Initial dose: 2-10 mcg/kg/min intravenously (IV)
Maintenance dose: 2-50 mcg/kg/min intravenously (IV)
Dosage forms and strengths
Solution-IV
0.8 mg/mL
1.6 mg/mL
3.2 mg/mL
40 mg/mL
Solution-IV (as hydrochloride)
40 mg/ml
continuous infusion:
2-10 mcg/kg/min IV
2-50 mcg/kg/min IV
Congestive Heart Failure (CHF)
continuous infusion:
2-10 mcg/kg/min IV
2-50 mcg/kg/min IV
continuous infusion:
2-10 mcg/kg/min IV
2-50 mcg/kg/min IV
continuous infusion:
2-10 mcg/kg/min IV
2-50 mcg/kg/min IV
It may increase the adverse effect when combined with hyaluronidase
may increase the hypertensive effect of Monoamine Oxidase Inhibitors
may increase the toxic effect of hyaluronidase
it may diminish the excretion rate when combined with permethrin, resulting in an enhanced serum level
it may diminish the excretion rate when combined with corifollitropin alfa resulting in an enhanced serum level
dopamine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
may enhance the risk or severity of hypertension when combined
administration of caffeine with dopamine reduces sedation
Actions and Spectrum:
Actions:
Dopamine is released from hypothalamus generated by adrenal gland enables communication and synchronizes messages between brain and body which controls hormones.
Spectrum:
This drug could keep emotions in control, movements, memory, insulin, blood vessel function, and immune system activity, thereby acts as “fight-or-flight” response.
Frequency Not Defined
Ventricular arrhythmia
palpitation
hypotension
vasoconstriction
Dyspnea
Nausea
vomiting
Azotemia
Headache, anxiety
Piloerection
Black Box Warning:
This drug shows serious adverse events with MAOI’s.
Contraindication/Caution:
Contraindications
Cautions
Pregnancy warnings:
Pregnancy Category: C
Breastfeeding warnings:
The release of the drug into the human breastmilk is unknown
Pregnancy Categories:
Pharmacology:
Pharmacodynamics:
Dopamine influences body functions by attaching to D1 receptors which raise cAMP levels and D2-like receptors. It stimulates adenylate cyclase and activates beta-1 adrenergic receptors to improve heart function and vasodilation through D1 receptors.
Pharmacokinetics:
Absorption
Rapid absorption
Metabolism
Biotransformation results into HVA and DOPAC
Elimination and Excretion
The half-life is 2 minutes
The drug (HVA) is excreted 80 % in urine.
Administration:
Administered through an intravenous (IV) injection.
Patient Information Leaflet
Generic Name: dopamine
Pronunciation: DOE-pa-meen
Why do we use dopamine?
Dopamine belongs to the class Catecholamines, Inotropic agents, Vasopressors used to treat heart attack, trauma, surgery, myocardial infarction, and renal failure.
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