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Brand Name :
Ebernet, Ebspor, Ebermac, Crurix, Eberwin, Eberderm, Eberclin
Synonyms :
eberconazole
Class :
Antifungal, Topical imidazole derivative
Dosage Forms & Strengths
Cream
15 gm
30 gm
40 gm
Apply a thin layer of cream into the affected areas of skin topically for two times in a day
Dosage Forms & Strengths
Cream
15 gm
30 gm
40 gm
For 13 to 18 years old:
Apply a thin layer of cream into the affected areas of skin topically for two times in a day
Refer to adult dosing
Actions and Spectrum
eberconazole exerts its antifungal action by inhibiting the synthesis of ergosterol, an important component of the fungal cell membrane. Ergosterol is essential for maintaining the integrity and function of the fungal cell membrane.
Frequency not defined
Itching
Burning
Irritation
Redness
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
eberconazole has its antifungal activity by inhibiting the synthesis of ergosterol, which is a vital component of the fungal cell membrane. eberconazole disrupts the fungal cell membrane, leading to increased permeability and causing cell death.
Pharmacodynamics
The inhibition of ergosterol synthesis results in change of the fungal cell membrane, leading to increased membrane permeability and leakage of cellular components.
Pharmacokinetics
Limited information available on ADME.
Administration
eberconazole is applied topically on skin and it is available in form of cream.
Patient information leaflet
Generic Name: eberconazole
Why do we use eberconazole?
Ebernet (eberconazole) is used in the treatment of fungal infections including skin and nails.
eberconazole is also used to treat tinea and candidiasis (related with feet and toes) infections.
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