Fame and Mortality: Evidence from a Retrospective Analysis of Singers
November 26, 2025
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Brand Name :
alcohol (ethyl)
Synonyms :
ethanol
Class :
Antidotes, Other
Brand Name :
alcohol (ethyl)
Synonyms :
ethanol
Class :
Antidotes, Other
Dosage forms & Strengths:
Adult:
Solution for injection (95%)
1 ml
5 ml
Solution for injection (95%)
1 ml
5 ml
Refer to the adult dosing
may increase the risk or severity of methemoglobinemia when miltefosine is combined
it increases the toxicity of cysteamine
excessive ethanol with miglitol alters the blood sugar level
excessive ethanol with acarbose alters the blood sugar level
ethanol and sitagliptin alter the glycemic control when used simultaneously
ethanol and linagliptin alter the glycemic control when used simultaneously
It may enhance sedation when combined with a shepherd's purse
it may enhance the sedation when combined with lofexidine
It may enhance the sedation when combined with tasimelteon
it may diminish the metabolism when combined with diosmin
when both drugs are combined, there may be an increased risk of adverse effects  
may increase the toxic effects of acetohydroxamic acid
When ethanol is aided by hesperetin, it reduces hesperetin’s metabolism
metronidazole enhances the effect of ethanol by altering the intestinal or hepatic CYP2E1 enzyme metabolism
ethanol and droperidol increase the toxicity of each other
Actions and Spectrum:
ethanol reacts with methanol and ethylene glycol to inhibit the production of metabolites that are toxic.
Frequency Not Defined:
Flushing hypotension
Intoxication
Hypoglycemia
Agitation
Intoxication
Polyuria
Black Box Warning:
It is essential to follow the dosage and administration instructions for the medication carefully.
Contraindication/Caution:
Patients with type 1 diabetes show contraindications for chlorpropamide. It is also contraindicated in patients with severe renal or hepatic impairment, as these patients may be at increased risk for adverse effects from the drug.
chlorpropamide should be used with caution in elderly patients.
Pregnancy consideration:
Category C.
Breastfeeding warnings:
Use with caution during breastfeeding.
Pregnancy category:
Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology
The primary metabolic pathway is oxidation by the enzyme alcohol dehydrogenase, which converts ethanol to acetaldehyde, which is further metabolized to acetic acid.
Pharmacodynamics:
The pharmacodynamics of ethanol involves its interactions with various neurotransmitter systems and receptors in the brain. ethanol enhances the effects of neurotransmitters such as GABA (gamma-aminobutyric acid), which leads to the inhibition of neurotransmission and CNS depression.
Pharmacokinetics:
Pharmacokinetics studies how a drug is absorbed, distributed, metabolized, and eliminated by the body. The following parameters can describe the pharmacokinetics of ethanol.
Absorption
The half-life of ethanol is 15-20 mg/dL/hr
Distribution
The volume of distribution is 0.6-0.7 L/kg
Metabolism
ethanol is metabolized in the liver.
Elimination and excretion
The drug is excreted in through the lungs and urine.
Administration:
ethanol is administered orally or intravenously.
Patient information leaflet
Generic Name: ethanol
Pronounced: eth-a-nol
Why do we use ethanol?
ethanol is used to treat methanol toxicity.
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