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Brand Name :
Nethaprin
Synonyms :
Etafedrine, ethylephedrine
Class :
Decongestants, Long-Acting Bronchodilator, Sympathomimetic Agent, Beta2-Adrenergic receptor agonist
Brand Name :
Nethaprin
Synonyms :
Etafedrine, ethylephedrine
Class :
Decongestants, Long-Acting Bronchodilator, Sympathomimetic Agent, Beta2-Adrenergic receptor agonist
Dosage Forms & Strengths
Syrup
50 ml
5 ml of this drug every 3 to 5 hours is recommended, which should be at most 30 ml daily
This drug is used for treating bronchial congestion and bronchospasm, which are associated with acute and chronic bronchitis
5 ml of this drug every 3 to 5 hours is recommended, which should be at most 30 ml daily
This drug is used for treating bronchial congestion and bronchospasm, which are associated with acute and chronic bronchitis
5 ml of this drug every 3 to 5 hours is recommended, which should be at most 30 ml daily
This drug is used for treating bronchial congestion and bronchospasm, which are associated with acute and chronic bronchitis
For children who are between 1 and 6 years of age, the recommended dose is 1.25 ml to 5 ml every 3 to 5 hours but should not exceed a maximum of 3 doses in a day, and for children who are between 6 and 12 doses is2.5 ml to 5 ml every 3 to 5 hours but should not exceed 15 ml in a day
For children who are between 1 and 6 years of age, the recommended dose is 1.25 ml to 5 ml every 3 to 5 hours but should not exceed a maximum of 3 doses in a day, and for children who are between 6 and 12 doses is2.5 ml to 5 ml every 3 to 5 hours but should not exceed 15 ml in a day
Refer to the adult dosing
Actions and Spectrum:
Actions:
Sympathomimetic agent etafedrine is used as a long-acting bronchodilator that acts on its sympathetic receptors of the bronchioles, which induce its action by relaxing spasms and help in controlling cough associated with inflammation of the mouth and throat by narrowing blood vessels in the nasal passages, which relieve nasal stuffiness.
Spectrum:
The spectrum of etafedrine includes treating bronchospasm, acute and chronic bronchitis, bronchial congestion, asthma, and cough.
Frequency Not defined
Irregular heartbeat
Swelling of face
Increased sweating
Rash
Redness of face
Ringing in ears
Hallucinations
Shortness of breath
Wheezing
Restless ness
Excitement in children
Trembling
Black Box Warning:
Seek immediate medical attention if blood pressure falls, pinpoint pupils of eyes, seizures, dizziness, restlessness, vomiting, and nausea occur
Contraindication/Caution:
Contraindications
Cautions
Pregnancy consideration:
This drug should not be administered during the first trimester of pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of drug in breast milk.
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
Sympathomimetic agent etafedrine is used as a long-acting bronchodilator that acts on its sympathetic receptors of the bronchioles, which induce its action by relaxing spasms and help in controlling cough associated with inflammation of the mouth and throat by narrowing blood vessels in the nasal passages, which relieve nasal stuffiness.
Pharmacodynamics:
Sympathomimetic agent etafedrine is used as a long-acting bronchodilator that acts on its sympathetic receptors of the bronchioles, which induce its action by relaxing spasms and help in controlling cough associated with inflammation of the mouth and throat by narrowing blood vessels in the nasal passages, which relieve nasal stuffiness. Unlike ephedrine, etafedrine will only show a bronchodilator effect by acting as a selective beta two adrenergic receptor agonist.
Pharmacokinetics:
Absorption
It is readily absorbed from GIT.
The time to achieve peak effect is 1 hour.
Distribution
The volume of distribution of etafedrine: 3 L/kg
Metabolism
Not Available
Elimination and Excretion
The half-life is 3-6 hours
The drug is excreted in urine.
Administration:
etafedrine is used as an expectorant and measured with a teaspoon taken orally.
Patient information leaflet
Generic Name: ethylephedrine
Pronounced: ETH-ul-eh-FED-rin
Why do we use ethylephedrine?
ethylephedrine is used for relief in case of chest tightness and wheezing that is associated with bronchial asthma and for relief in case of shortness of breath. ethylephedrine is a bronchodilator and decongestant which allows patients to breathe with ease.
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