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Brand Name :
evkeeza
Synonyms :
Evinacumab, evinacumab-dgnb
Class :
Monoclonal antibody, antihyperlipidemic agents
Brand Name :
evkeeza
Synonyms :
Evinacumab, evinacumab-dgnb
Class :
Monoclonal antibody, antihyperlipidemic agents
Dosage Forms & Strengths
Injection, solution:
345mg/2.3ml(150mg/ml)
1200mg/8ml(150mg/ml)
Administer 15mg/kg intravenous once a month
Dosage Forms & Strengths
Injection, solution:
345mg/2.3ml(150mg/ml)
1200mg/8ml(150mg/ml)
<12 years: Safety and efficacy not established
>12 years:15mg/kg intravenous once a month
Refer adult dosing
may decrease the therapeutic effect of Fc Receptor-Binding agents
Frequency defined:
>10%
Nasopharyngitis
1-10%
Infusion-related reactions
Rhinorrhea
Pain in extremity
Nasal congestion
Anaphylactic shock
Influenza-like illness
Nausea
Dizziness
Asthenia
Upper respiratory tract infection
Abdominal pain
Pregnancy consideration: Insufficient data available
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient information leaflet
Generic Name: evinacumab
Pronounced: (E-vin-AK-ue-mab)
Why do we use evinacumab?
It is used to treat homozygous familial hypercholesterolemia
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