Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Balsacetil, Broncaspin, Prontomucil, Guaiaspir
Synonyms :
guasetisal
Class :
Anti-inflammatory/ Salicylic acid derivatives
Brand Name :
Balsacetil, Broncaspin, Prontomucil, Guaiaspir
Synonyms :
guasetisal
Class :
Anti-inflammatory/ Salicylic acid derivatives
Dosage Forms & StrengthsÂ
CapsulesÂ
10mgÂ
25mgÂ
50mgÂ
100mgÂ
250mgÂ
SuspensionÂ
3.3%Â
5%Â
1 - 1.5
g
Orally 
once a day
Indications: indicated in the treatment of aspirin-asthma, chronic bronchitis
Dosage Forms & StrengthsÂ
SuppositoryÂ
0.5g/dieÂ
SuspensionÂ
3.3%Â
5%Â
Off-label
1-2 suppositories, administered rectally for children under 6 years
2 suppositories administered rectally for children above 6 years
Indications: indicated in the treatment of inflammations of airways in infants in acute diseases
Refer to adult dosingÂ
the rate of excretion of abacavir may be reduced
the risk of hemorrhage and bleeding may be increased
the hypoglycaemic effects of acarbose may be increased
the antihypertensive effect of acebutolol may be reduced
the risk of hemorrhage and bleeding may be increased
the risk of adverse effects may be increased
the serum levels of acetyldigoxin may be reduced
the therapeutic activity of guacetisal may be reduced
the rate of excretion of aclidinium may be reduced
the risk of nephrotoxicity may be increased
the risk of adverse effects may be increased
the rate of excretion of almasilate may be reduced
the risk of hemorrhage and bleeding can be increased
the risk of nephrotoxicity may be increased
the risk of hypertension, renal failure, and hyperkalemia may be increased
the risk of hypertension may be increased
Actions and spectrum:Â
Guacetisal acts as an anti-inflammatory by inhibiting cyclooxygenase, thereby blocking prostaglandin synthesis. It also acts centrally on the cough center that helps to suppress coughÂ
Frequency not definedÂ
AnorexiaÂ
Rashes on skinÂ
EpistaxisÂ
TinnitusÂ
NauseaÂ
Vomiting
Black Box Warning Â
Not listedÂ
Contraindication/Caution:Â
Contraindication:Â
HypersensitivityÂ
Renal impairmentÂ
Liver cirrhosisÂ
AsthmaÂ
Bleeding diathesisÂ
Gastroduodenal ulcerÂ
Gout Â
Pregnancy consideration:Â Â
USFDA pregnancy category: Not assignedÂ
Lactation:Â Â
Data about the excretion of guacetisal into breast milk is not known.Â
Pregnancy category:Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.Â
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
Pharmacology:Â
Guacetisal is synthesized from aspirin and guaiacol by esterification reaction.Â
Pharmacodynamics:Â
It blocks the prostaglandin synthesis by inhibiting the activity of the enzyme cyclooxygenase. It is also known to suppress cough by acting on the medullary cough centreÂ
Pharmacokinetics:Â
AbsorptionÂ
Following oral administration, the drug is absorbed rapidly in the g.i.tract, and the unchanged form is seen in the blood. Â
MetabolismÂ
Undergoes hepatic metabolism to guajacholic ester of salicylic acid by esterases. This is, inturn, broken down into guajacol and salicylic acid by hepatic esterases.Â
Elimination and excretionÂ
Guacetisal is excreted renally.Â
Administration:Â
To be administered after foodÂ
Patient information leafletÂ
Generic Name: guacetisal Â
Why do we use guacetisal?Â
Guacetisal is a derivative of salicylic acid used in the treatment of inflammations in the upper and lower respiratory tract. It is also used to treat cough and inflammation in infants caused by acute diseases.Â
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