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Brand Name :
N/A
Synonyms :
Henbane, Witch’s drug, stinking Nightshade
Class :
Anti-spasmodic agent
Brand Name :
N/A
Synonyms :
Henbane, Witch’s drug, stinking Nightshade
Class :
Anti-spasmodic agent
Dosage Forms & Strengths
Dosage Forms & Strengths
Data not available
Refer to adult dosing
Actions and spectrum:
Action:
Henbane’s key compounds are tropane alkaloids like scopolamine and hyoscyamine. These substances relax muscles, especially digestive ones, relieving gut spasms and discomfort. They soothe the central nervous system too, calming anxiety and restlessness. Furthermore, they reduce involuntary muscle movements, treating tremors. In summary, henbane’s tropane alkaloids are crucial for its therapeutic effects on gastrointestinal and neuromuscular issues.
Spectrum:
Henbane can help with muscle cramps, stomach pains, and scars.
Frequency not defined
Constipation
Dry mouth
Red skin
Problems in urination
High doses of henbane can cause,
Reduced sweat
Drowsiness
Hallucinations
Increased heartbeat
Overheating
Vision disturbances
Manic episodes
Delirium and sometimes death
Black Box Warning
But, henbane is very dangerous if you take too much. Taking too much henbane could even kill you. That’s why you have to be very careful when using henbane products. Only take the right amount to avoid getting really sick.
Contraindication/Caution:
Contraindication:
Down syndrome
Heart failure
Tachycardia
Constipation
Narrow-angle glaucoma
Fever
Urinary retention
Digestive disorders
Toxic megacolon
Pregnancy consideration:
The drug is not safe to be used in pregnancy
Lactation:
The drug is not safe to be used in breastfeeding
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Henbane, also called Hyoscyamus niger, falls into the Solanaceae family. Tomatoes and potatoes belong here too. Henbane holds toxic alkaloids like hyoscyamine and scopolamine. These chemicals impact the central nervous system. This affects physical state and mental state when ingested. Henbane’s toxicity means handling with care. Medical use requires expertise and oversight. Never use without proper knowledge and guidance.
Pharmacodynamics:
Limited data available
Pharmacokinetics:
Limited data available
Administration:
Limited data available
Patient information leaflet
Generic Name: henbane
Pronounced: hen-bae-en
Why do we use henbane?
Henbane contains alkaloids that produce effects. For instance, hyoscyamine and scopolamine contribute to bronchodilation. They promote sedation too. Additionally, the alkaloids relax muscles and dilate pupils. Their anti-diarrheal properties are notable. Generally, henbane demonstrates pharmacological attributes due to these substances.
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