ipriflavone

Action and Spectrum

Actions and Spectrum 

ipriflavone is a synthetic flavonoid derivative primarily used as a dietary supplement.  

ipriflavone stimulates new bone development by stimulating osteoblasts and reduces bone resorption by inhibiting osteoclasts.

Drug Interaction

Adverse Reaction

Frequency not defined  

Lymphopenia 

Black Box Warning

Black Box Warning 

None

Contraindication / Caution

Contraindication/Caution: 

Contraindication: 

None  

Caution: 

• Caution should be taken in women with history of oestrogen-dependent breast cancer. 

Pregnancy / Lactation

Pregnancy consideration: 

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

ipriflavone also promotes the activity of osteoblasts, cells responsible for building new bone tissue. This effect can help increase bone density. 

Pharmacodynamics 

ipriflavone may enhance the uptake of calcium by bone cells and reduce the release of calcium from bones.  

Pharmacokinetics 

Absorption   

ipriflavone is absorbed from the gastrointestinal tract into the bloodstream.  

Distribution 

ipriflavone is distributed throughout the body.  

Metabolism 

ipriflavone is metabolized in the liver. 

Elimination and excretion 

ipriflavone is excreted through the kidneys in the urine. 

Adminstartion

Administration 

ipriflavone is available in tablet or capsule form and administered orally as a dietary supplement. 

Patient Information Leaflet

Patient information leaflet 

Generic Name: ipriflavone 

Why do we use ipriflavone? 

ipriflavone is used as a dietary supplement to support bone health and manage osteoporosis.  

ipriflavone may be used to increase bone mineral density.