Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Compound sodium lactate
Synonyms :
lactated Ringer solution
Class :
Electrolyte Supplement, Parenteral
Brand Name :
Compound sodium lactate
Synonyms :
lactated Ringer solution
Class :
Electrolyte Supplement, Parenteral
Adult
Solution
250 ml
500 ml
1000 ml
Irrigation solution
1000 ml
2000 ml
3000 ml
4000 ml
5000 ml
Alkalinizing Agent, Replacement
Indicated for Alkalinizing agent, replacement
Intravenous solution: Volume, duration, and rate shall be personalized and contingent on the purpose of administration, patient's age, body weight, concurrent therapy, medical state, and the laboratory assessments
Irrigation
Dosage varies according to the extent of the area to be irrigated and the specific process involved
Sepsis-induced hypoperfusion/Septic shock, fluid resuscitation as Off-label
Intravenous solution: 30ml/Kg of body weight, which is the minimum dosage administered in the 1st three hours for hypotension or shock
Solution
250 ml
500 ml
1000 ml
Irrigation solution
1000 ml
2000 ml
3000 ml
4000 ml
5000 ml
Indicated for Septic shock
Intravenous solution:10 ml/Kg or 20 ml/Kg administered
Reassess it as often, If required, repeat it
Refer to adult dosing
The solution maintains normal cellular and tissue function to provide essential electrolytes. It restores extracellular fluid volume to maintain blood pressure and improve perfusion.
Frequency not defined:
Pain
Swelling
Redness
None
Contraindications:
Severe liver disease
Metabolic alkalosis
Cautions:
Renal impairment
Edema and fluid overload
Blood transfusion
Pregnancy category: C
Lactation: Excretion of the drug into the human breast milk is unknown
Pregnancy categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Lactated Ringer’s solution is a sterile and isotonic intravenous fluid composed of sodium chloride, sodium lactate, potassium chloride, and calcium chloride. The solution is useful to maintains fluid and electrolyte balance in the body.
Pharmacodynamics:
Lactated Ringer’s solution raises the fluid volume for balanced extracellular hydration. The high amount of plasma volume increases cardiac output and blood pressure to provide better oxygen supply.
Pharmacokinetic:
Limited information available on ADME.
It is administered intravenously in the injection form.
Generic Name: Lactated Ringer solution
Why do we use Lactated Ringer solution?
Lactated ringer solution is used in cases of blood/fluid loss due to trauma, surgery, and burns.
It is indicated to maintain normal fluid and electrolyte levels during surgery to avoid hypovolemia.
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