Genomic Study Maps Shared Risk Factors for 14 Psychiatric Disorders
December 14, 2025
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Brand Name :
Nucala
(United States) [Available]Synonyms :
mepolizumab
Class :
Drugs for asthma and COPD & Anti-Asthmatic (monoclonal antibody)
Dosage Forms & Strengths
Prefilled syringe with solution, Subcutaneous:
40 mg/0.4ml (1 ml)
100 mg/ml (1 ml)
Solution reconstituted and auto-injector, subcutaneous:
100 mg
100
mg
Subcutaneous (SC)
4
weeks
Dosage Forms & Strengths
Prefilled syringe with solution, Subcutaneous:
40 mg/0.4ml (1 ml)
100 mg/ml (1 ml)
Solution reconstituted and auto-injector, subcutaneous:
100 mg
Age: 6-12 years
40 mg subcutaneous (SC) every 4 weeks
Age: >12 years
100 mg subcutaneous (SC) every 4 weeks
Refer to adult dosing
it may enhance the adverse effects when combined with aducanumab
may increase the risk or severity of adverse effects when combined
it may diminish the excretion rate when combined with quinolones, resulting in an enhanced serum level
it may diminish the excretion rate when combined with quinolones, resulting in an enhanced serum level
may increase the risk of sedation
may increase the risk of sedation
may increase the risk of sedation
may increase the risk of sedation
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
aspirin, chlorpheniramine, and phenylephrine
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
Frequency defined:
>10%
Injection site reaction
Pain at the injection site
Swelling at the injection site
headache
1% to 10%
Eczema
Pruritis
Skin rash
Diarrhea
Urinary tract infection
Angioedema
Hypersensitivity reactionarthralgia
Dry nose
Fever
Frequency not defined:
Herpes zoster infection
Post-marketing
Angioedema
Hypersensitivity reaction
Pregnancy consideration: only preferred if conventional therapies do not work to treat asthma in pregnancy.
Lactation: Mepolizumab excretion in breast milk is not known.
Pregnancy category:
Patient information leaflet
Generic Name: Mepolizumab
Pronounced: me-po -li-zu-mab
Why do we use mepolizumab?
Mepolizumab is used to treat asthma, eosinophilic granulomatosis with polyangiitis, hypereosinophilic syndrome, sinus problems with nasal polyps. It can also be prescribed by your doctor for other conditions. For asthma attack use a rescue inhaler and talk with your doctor
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