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Brand Name :
Meptid
Synonyms :
meptazinol
Class :
Opioid analgesics
Dosage Forms & Strengths
Tablets
200mg
200
mg
Tablets
Orally
4 to 8 times a day
The usual recommended dose is 200mg orally every 4 hours indication: it is usually indicated in the treatment of moderate pain
Safety and efficacy study is not established
Refer to adult dosing
the risk of central nervous system depression may be increased
the risk of CNS depression and hypotension may be increased
the risk of adverse effects may be increased
the risk of CNS depression may be increased
the therapeutic activity of alfentanil may be reduced
the risk of CNS depression and hypotension may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of adverse effects may be increased
the risk of adverse effects may be increased
the risk of adverse effects may be increased
the therapeutic activity of amiloride may be reduced
the analgesic activity of meptazinol may be increased
the risk of adverse effects may be increased
the risk of CNS depression may be increased
the risk of adverse effects may be increased
the risk of adverse effects may be increased
the risk of CNS depressant activity of meptazinol may be increased
Actions and spectrum:
Meptazinol is a pain-relieving drug. It belongs to the opioid family. That means it attaches to opioid receptors. These are located in your brain and spinal cord. When meptazinol binds to these receptors, it alters pain signals. As a result, you feel less pain. Meptazinol works on different types of pain. These include nociceptive, neuropathic, and inflammatory pain. It can treat moderate to severe pain levels. Despite its potency, meptazinol generally has manageable side effects. For these reasons, doctors find it useful for managing pain.
Frequency not defined
Abdominal pain
Bradycardia
Constipation
Diarrhea
Dyspepsia
Headache
Hypotension
Miosis
Mood changes
Respiratory depression
Tachycardia
Sweating
Tolerance
Edema
Palpitations
Pruritis
Somnolence
Urticaria
Visual disturbances
vertigo
Black Box Warning
Recommended for short-term use only
Contraindication/Caution:
Contraindication:
Acute asthma
Coma
Trauma of head
Myocardial infarction
Acute alcohol intoxication
Phaeochromocytoma
Acute respiratory depression
Increase in intracranial pressure
Caution:
Debilitation
Adrenal insufficiency
Pregnancy
Breastfeeding
Respiratory impairment
Urethral stricture
Myasthenia gravis
Hypothyroidism
Hepatic failure
Pregnancy consideration:
To be used with caution in pregnancy
Lactation:
To be used with caution in breastfeeding
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Meptazinol, a painkiller, functions in the brain and spinal cord. It attaches to mu opioid receptors, stopping pain signals. It also binds with kappa and delta opioid receptors. Unlike some opioids, meptazinol has a limit on breathing problems, making it safer. It may also numb pain locally, helping relief.
Pharmacodynamics:
Limited data available
Pharmacokinetics:
Limited data available
Administration:
To be taken orally with plenty of water
Patient information leaflet
Generic Name: meptazinol
Why do we use meptazinol?
Meptazinol works as an opioid pain medicine. It helps treat moderate discomfort by binding to specific receptors found in the brain and spine that control pain perception. The medicine interacts with these receptors, altering how pain signals are processed, ultimately reducing pain levels. Doctors prescribe meptazinol for managing moderate pains like those after surgery, muscle/joint aches, plus acute or chronic discomforts. By attaching to opioid receptors centrally and in the spinal cord, meptazinol provides effective relief when moderate analgesia is needed.