Alcohol Consumption Emerges as a Key Risk Factor for Buccal Cancer in India
December 24, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Moxocard, Moxodil
Synonyms :
moxonidine
Class :
Antihypertensives agent
Brand Name :
Moxocard, Moxodil
Synonyms :
moxonidine
Class :
Antihypertensives agent
Dosage Forms & Strengths
Tablet
0.2 mg
0.3 mg
Take an initial dose of 200 mcg orally one time daily in the morning, then it may raise if required; after 3 weeks, up to 400 mcg daily as a single dose
Not determined
Refer to adult dosing
moxonidine: it may decrease activities of antihypertensive drugs
moxonidine: it may decrease activities of antihypertensive drugs
moxonidine: it may decrease activities of antihypertensive drugs
moxonidine: it may decrease activities of antihypertensive drugs
moxonidine: it may decrease activities of antihypertensive drugs
Actions and Spectrum
moxonidine stimulates alpha-2 adrenergic receptors in the brainstem. This results in decreased nerve signals to the blood vessels and the heart, leading to relaxation of blood vessels and a decrease in heart rate and cardiac output.
Frequency not defined
Bradycardia
Tinnitus
headache
Dizziness
Somnolence
Syncope
Hypotension
Diarrhea
Dry mouth
Nausea
Vomiting
Dyspepsia
Pruritus
Angioedema
Oedema
Insomnia
Nervousness
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
moxonidine’s pharmacological effect is the reduction of blood pressure.
By activating central alpha-2 adrenergic receptors, it reduces the release of norepinephrine, which in turn reduces sympathetic outflow from the central nervous system.
Pharmacodynamics
moxonidine’s primary therapeutic effect is the reduction of blood pressure.
The combined effects of vasodilation, decreased cardiac output, and reduced sympathetic activity led to a decrease in both systolic and diastolic blood pressure.
Pharmacokinetics
Absorption
moxonidine is well-absorbed when taken orally.
The peak plasma concentrations of moxonidine are reached within 2 to 4 hours after oral administration.
Distribution
moxonidine is distributed throughout the body.
Metabolism
moxonidine undergoes hepatic metabolism to form metabolites.
Elimination and excretion
moxonidine is primarily excreted in urine. The elimination half-life of moxonidine is approximately 2 to 3 hours.
Administration
moxonidine is administered orally and available in the form of a tablet.
Patient information leaflet
Generic Name: moxonidine
Why do we use moxonidine?
moxonidine is used for the management of hypertension.
moxonidine is also used to help manage symptoms of opioid withdrawal.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
