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Brand Name :
Talacen
Synonyms :
pentazocine/acetaminophen
Class :
Analgesics, Opioid Combos; Analgesics, Opioid Partial Agonist
Dosage Forms & Strengths
Tablet
25mg/650mg
(pentazocine/acetaminophen)
1
Tablet
Orally
every 4 hrs
Do not exceed 6 tablets per day
Dosage Forms & Strengths
Tablet
25mg/650mg
(pentazocine/acetaminophen)
1
Tablet
Orally
every 4 hrs
Do not exceed 6 tablets per day
Refer adult dosing
Action and spectrum:
Pentazocine/acetaminophen is a combination of two drugs which relieves pain.
Pentazocine is an opioid that works on opioid receptors and acetaminophen is an analgesic that relieves pain by preventing the production of certain chemicals.
Frequency Not Defined
For Pentazocine
Circulatory depression
Depression
Floating feeling
Cramps
Nausea, vomiting
Abdominal distress
Apprehension
Confusion and hallucinations
Constipation
Blurred vision
For Acetaminophen
Angioedema
Pruritic maculopapular
Urticaria
Agranulocytosis, leukopenia
Thrombocytopenic purpura
Hepatotoxicity
Black box warning
None
Contraindication and caution
Contraindications
Cautions
Pregnancy Warnings:
Pregnancy category: C (pentazocine)
Lactation: Excretion of the drug into the human breast milk is unknown
Pregnancy categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology:
Pentazocine is an opioid agonist which causes changes in response to pain.
While acetaminophen is a nonsalicylate analgesic which may block pain impulses.
Pharmacodynamics:
Limited information is available.
Pharmacokinetics:
Limited data is available on ADME as drug is discontinued.
Administration:
It is taken orally in the form of tablets.
Patient information leaflet
Generic Name: pentazocine/acetaminophen
Why do we use pentazocine/acetaminophen?
Pentazocine/acetaminophen is a combination drug used to treat mild-to-moderate pain.