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Brand Name :
Pneumovax-23, 23-valent, Pnu-Imune 23
Synonyms :
Pneumococcal polysaccharides vaccine(PPSV)
Class :
Bacterial vaccines, inactivated
Brand Name :
Pneumovax-23, 23-valent, Pnu-Imune 23
Synonyms :
Pneumococcal polysaccharides vaccine(PPSV)
Class :
Bacterial vaccines, inactivated
Dosage Forms & Strengths
Injectable solution (Vaccine)
0.5ml per dose
0.5
ml
Solution
Intramuscular (IM)
one time only
It is recommended for use in active immunization to prevent pneumococcal disease, which is caused by the vaccine's 23 serotypes.
Dosage Forms & Strengths
Injectable solution (Vaccine)
0.5ml per dose
0.5
ml
Intramuscular (IM)
one time only
Less than two years of age:
Safety study is not established
More than two years of age:
0.5ml intramuscular or subcutaneous, one time
Refer to adult dosing
the effect of pneumococcal vaccine polyvalent may be reduced due to immunosuppressive effects
the effects of either of the vaccines are reduced
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
The risk of infection can be increased due to the immunosuppressive effect
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
the activity of pneumococcal vaccine polyvalent is reduced due to pharmacodynamic antagonism
The risk of infection can be increased due to the immunosuppressive effect
It may enhance the risk of adverse effects when combined with Hypnotics
It may enhance the risk of adverse effects when combined with Hypnotics
It may enhance the risk of adverse effects when combined with Hypnotics
It may enhance the risk of adverse effects when combined with Hypnotics
It may enhance the risk of adverse effects when combined with Hypnotics
melphalan decreases the activity of pneumococcal vaccine polyvalent by antagonism.
Actions and spectrum
The capsular antigens of Streptococcus pneumonia stimulate the response of the immune system, which results in the production of endogenous antibodies.
Frequency not defined
Rashes
Hemolytic anemia
Anaphylactoid reaction
Guillain- Barre syndrome
Low-grade fever
Thrombocytopenia
Lymphadenitis
Erythema
Soreness at the site of injection
Angioedema
Black Box Warning
Never mix with other vaccines in the same vial or syringe
Contraindication/Caution:
Contraindication:
History of pneumococcal vaccine
Caution:
Heart disease
Impaired pulmonary function
Pregnancy consideration:
USFDA pregnancy category: study data not established
Lactation:
The excretion of this vaccine into human milk is unknown
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus `in either the first or second trimester.
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Pharmacodynamics:
Pharmacokinetics:
Limited data available
Absorption
Distribution
Metabolism
Elimination and excretion
Half-life:
Administration:
For subcutaneous or intramuscular administration only
Administer in the lateral or deltoid mid-thigh
Patient information leaflet
Generic Name: pneumococcal vaccine polyvalent
Why do we use the pneumococcal vaccine polyvalent?
An active immunization tool used to prevent pneumococcal bacterial infection is the pneumococcal polyvalent vaccine. It functions by triggering the immune system to generate antibodies, which are your body’s defense against the illness.
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